Graduate School of Biomedical Sciences

Student Publications and Awards

Master
Heading

Selected Student Publications: 2018 - 2020

Content

Our students frequently publish in top-tier, peer-reviewed journals and attend national and international meetings. A representative selection of recent student publications is presented below. Student names are bolded in lists of authors for each publication.

Biel N, Figard L, Sokac AM. Imaging Intranuclear Actin Rods in Live Heat Stressed Drosophila Embryos. J Vis Exp. 2020 May 15;(159):10.3791/61297. doi: 10.3791/61297. PMID: 32478727; PMCID: PMC7521865.

Blanco FA, Czikora A, Kedei N, You Y, Mitchell GA, Pany S, Ghosh A, Blumberg PM, Das J, 2019, Munc13 Is a Molecular Target of Bryostatin 1, Biochemistry (58): 3016-3030. PMCID:6620733; PMID: 31243993

Brown RM 2nd, Nelson JC, Zhang H, Kiernan AE, Groves AK, 2020, Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development., Developmental biology (462): 74-84. PMCID: 7261482, PMID: 32147304

Brunetti L, Gundry MC, Sorcini D, Guzman AG, Huang YH, Ramabadran R, Gionfriddo I, Mezzasoma F, Milano F, Nabet B, Buckley DL, Kornblau SM, Lin CY, Sportoletti P, Martelli MP, Falini B, Goodell MA, 2018, Mutant NPM1 Maintains the Leukemic State through HOX Expression., Cancer cell (34): 499-512.e9. PMCID:6159911, PMID: 30205049

Burger CA, Alevy J, Casasent AK, Jiang D, Albrecht NE, Liang JH, Hirano AA, Brecha NC, Samuel MA. LKB1 coordinates neurite remodeling to drive synapse layer emergence in the outer retina. Elife. 2020 May 7;9:e56931. doi: 10.7554/eLife.56931. PMID: 32378514; PMCID: PMC7237215.

Chang-Graham AL, Perry JL, Engevik MA, Engevik KA, Scribano FJ, Gebert JT, Danhof HA, Nelson JC, Kellen JS, Strtak AC, Sastri NP, Estes MK, Britton RA, Versalovic J, Hyser JM. Rotavirus induces intercellular calcium waves through ADP signaling. Science. 2020 Nov 20;370(6519):eabc3621. doi: 10.1126/science.abc3621. PMID: 33214249; PMCID: PMC7957961.

Chen MS, Lo YH, Chen X, Williams CS, Donnelly JM, Criss ZK 2nd, Patel S, Butkus JM, Dubrulle J, Finegold MJ, Shroyer NF. Growth Factor-Independent 1 Is a Tumor Suppressor Gene in Colorectal Cancer. Mol Cancer Res. 2019 Mar;17(3):697-708. doi: 10.1158/1541-7786.MCR-18-0666. Epub 2019 Jan 3. PMID: 30606770; PMCID: PMC7387124.

Clark J, Terwilliger A, Nguyen C, Green S, Nobles C, Maresso A. Heme catabolism in the causative agent of anthrax. Mol Microbiol. 2019 Aug;112(2):515-531. doi: 10.1111/mmi.14270. Epub 2019 May 27. PMID: 31063630; PMCID: PMC7515447.

Cristobal CD, Ye Q, Jo J, Ding X, Wang CY, Cortes D, Chen Z, Lee HK. Daam2 couples translocation and clustering of Wnt receptor signalosomes through Rac1. J Cell Sci. 2020 Dec 11:jcs.251140. doi: 10.1242/jcs.251140. Epub ahead of print. PMID: 33310913.

Ding X, Jo J, Wang CY, Cristobal CD, Zuo Z, Ye Q, Wirianto M, Lindeke-Myers A, Choi JM, Mohila CA, Kawabe H, Jung SY, Bellen HJ, Yoo SH, Lee HK. The Daam2-VHL-Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation. Genes Dev. 2020 Sep 1;34(17-18):1177-1189. doi: 10.1101/gad.338046.120. Epub 2020 Aug 13. PMID: 32792353; PMCID: PMC7462057.

Gibson SB, Green SI, Liu CG, Salazar KC, Clark JR, Terwilliger AL, Kaplan HB, Maresso AW, Trautner BW, Ramig RF, 2019, Constructing and Characterizing Bacteriophage Libraries for Phage Therapy of Human Infections., Frontiers in microbiology (10): 2537. PMCID:6861333, PMID: 31781060

Gu G, Tian L, Herzog SK, Rechoum Y, Gelsomino L, Gao M, Du L, Kim JA, Dustin D, Lo HC, Beyer AR, Edwards DG, Gonzalez T, Tsimelzon A, Huang HJ, Fernandez NM, Grimm SL, Hilsenbeck SG, Liu D, Xu J, Alaniz A, Li S, Mills GB, Janku F, Kittler R, Zhang XH, Coarfa C, Foulds CE, Symmans WF, Andò S, Fuqua SAW. Hormonal modulation of ESR1 mutant metastasis. Oncogene. 2021 Feb;40(5):997-1011. doi: 10.1038/s41388-020-01563-x. Epub 2020 Dec 15. Erratum in: Oncogene. 2021 Nov 15;: PMID: 33323970; PMCID: PMC8020875.

Hu X, Harvey SE, Zheng R, Lyu J, Grzeskowiak CL, Powell E, Piwnica-Worms H, Scott KL, Cheng C, 2020, The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing. Nature communications (11): 486. PMCID:6981122, PMID: 31980632

Hu X., Harvey S.E., Zheng R., Lyu J., Grzeskowiak C., Powell E., Piwinica-Worms H., Scott K.L., Cheng C., 2019, The RNA Binding Protein AKAP8 acts as a Novel metastasis Suppressor by Antagonizing EMT Associated Alternative RNA Splicing. Nature (): . PMCID:, PMID:

Jarrett KE, Lee C, De Giorgi M, Hurley A, Gillard BK, Doerfler AM, Li A, Pownall HJ, Bao G, Lagor WR. Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research. Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):1997-2006. doi: 0.1161/ATVBAHA.118.311221. PubMed PMID: 30026278; PubMed Central PMCID: PMC6202188.

Jelinski J, Terwilliger A, Green S, Maresso A, 2020, Progress Towards the Development of a NEAT Vaccine for Anthrax II: Immunogen Specificity and Alum Effectiveness in an Inhalational Model., Infection and immunity (): . PMCID:, PMID: 32393506

Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, Jiang W, Arnold J, Gu F, He J, Jebakumar D, Walker K, Li Y, Mo Q, Westbrook TF, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XH. Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nat Cell Biol. 2019 Sep;21(9):1113-1126. doi: 10.1038/s41556-019-0373-7. Epub 2019 Aug 26. PubMed PMID: 31451770; PubMed Central PMCID: PMC6726554.

Lee WS, Lavery L, Rousseaux MWC, Rutledge EB, Jang Y, Wan YW, Wu SR, Kim W, Al-Ramahi I, Rath S, Adamski CJ, Bondar VV, Tewari A, Soleimani S, Mota S, Yalamanchili HK, Orr HT, Liu Z, Botas J, Zoghbi HY. Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1. EMBO J. 2021 Apr 1;40(7):e106106. doi: 10.15252/embj.2020106106. Epub 2021 Mar 11. PMID: 33709453; PMCID: PMC8013850.

Lee YT, Wang MC. The Bacterivore's Solution: Fight and Flight to Promote Survival. Dev Cell. 2019 Apr 8;49(1):7-9. doi: 10.1016/j.devcel.2019.03.021. PMID: 30965036.

Lemon LD, Morris DK, Bertuch AA. Loss of Ku's DNA end binding activity affects telomere length via destabilizing telomere-bound Est1 rather than altering TLC1 homeostasis. Sci Rep. 2019 Jul 23;9(1):10607. doi: 10.1038/s41598-019-46840-2. PMID: 31337791; PMCID: PMC6650470.

Lin SC, Qu L, Ettayebi K, Crawford SE, Blutt SE, Robertson MJ, Zeng XL, Tenge VR, Ayyar BV, Karandikar UC, Yu X, Coarfa C, Atmar RL, Ramani S, Estes MK. Human norovirus exhibits strain-specific sensitivity to host interferon pathways in human intestinal enteroids. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23782-23793. doi: 10.1073/pnas.2010834117. Epub 2020 Sep 9. PMID: 32907944; PMCID: PMC7519316.

Litvinchuk A, Wan YW, Swartzlander DB, Chen F, Cole A, Propson NE, Wang Q, Zhang B, Liu Z, Zheng H. Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease. Neuron. 2018 Dec 19;100(6):1337-1353.e5. doi:10.1016/j.neuron.2018.10.031. Epub 2018 Nov 8. PubMed PMID: 30415998; PubMed Central PMCID: PMC6309202.

Liu M, Wang X, Li W, Yu X, Flores-Villanueva P, Xu-Monette ZY, Li L, Zhang M, Young KH, Ma X, Li Y, 2020, Targeting PD-L1 in non-small cell lung cancer using CAR T cells., Oncogenesis (9): 72. PMCID:7426958, PMID: 32792499

Lo HC, Xu Z, Kim IS, Pingel B, Aguirre S, Kodali S, Liu Jun, Zhang W, Muscarella AM, Hein, SM, Krupnick AS,  Neilson JR, Paust S, Rosen JM, Wang H, Zhang, XH-F., 2020, Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis., Nature Cancer (1): 709-722. 

Madan A, Thompson D, Fowler JC, Ajami NJ, Salas R, Frueh BC, Bradshaw MR, Weinstein BL, Oldham JM, Petrosino JF. The gut microbiota is associated with psychiatric symptom severity and treatment outcome among individuals with serious mental illness. J Affect Disord. 2020 Mar 1;264:98-106. doi: 10.1016/j.jad.2019.12.020. Epub 2019 Dec 14. PMID: 32056780.

Nitschke L, Tewari A, Coffin SL, Xhako E, Pang K, Gennarino VA, Johnson JL, Blanco FA, Liu Z, Zoghbi HY, 2020, miR760 regulates ATXN1 levels via interaction with its 5' untranslated region., Genes & development (34): 1147-1160. PMCID:7462065, PMID: 32763910

Park CS, Lewis AH, Chen TJ, Bridges CS, Shen Y, Suppipat K, Puppi M, Tomolonis JA, Pang PD, Mistretta TA, Ma L, Green MR, Rau R, Lacorazza HD, 2019, A KLF4-DYRK2-mediated pathway regulating self-renewal in CML stem cells., Blood (134): 1960-1972. PMCID:6887114, PMID: 31515251

Pribis JP, García-Villada L, Zhai Y, Lewin-Epstein O, Wang AZ, Liu J, Xia J, Mei Q, Fitzgerald DM, Bos J, Austin RH, Herman C, Bates D, Hadany L, Hastings PJ, Rosenberg SM, 2019, Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response., Molecular cell (74): 785-800.e7. PMCID:6553487, PMID: 30948267

Schulze KV, Swaminathan S, Howell S, Jajoo A, Lie NC, Brown O, Sadat R, Hall N, Zhao L, Marshall K, May T, Reid ME, Taylor-Bryan C, Wang X, Belmont JW, Guan Y, Manary MJ, Trehan I, McKenzie CA, Hanchard NA, 2019, Edematous severe acute malnutrition is characterized by hypomethylation of DNA., Nature communications (10): 5791. PMCID:6923441, PMID: 31857576

Sheng K, Zong C. Single-Cell RNA-Seq by Multiple Annealing and Tailing-Based Quantitative Single-Cell RNA-Seq (MATQ-Seq). Methods Mol Biol. 2019;1979:57-71. doi: 10.1007/978-1-4939-9240-9_5. PubMed PMID: 31028632.

Zhang J, Kodali S, Chen M, Wang J. Maintenance of Germinal Center B Cells by Caspase-9 through Promotion of Apoptosis and Inhibition of Necroptosis. J Immunol. 2020 Jul 1;205(1):113-120. doi: 10.4049/jimmunol.2000359. Epub 2020 May 20. PMID: 32434938.

Vogt MB, Lahon A, Arya RP, Kneubehl AR, Spencer Clinton JL, Paust S, Rico-Hesse R. Mosquito saliva alone has profound effects on the human immune system. PLoS Negl Trop Dis. 2018 May 17;12(5):e0006439. doi:10.1371/journal.pntd.0006439. eCollection 2018 May. PubMed PMID: 29771921; PubMed Central PMCID: PMC5957326.

Wei X, Zhang L, Zhou Z, Kwon OJ, Zhang Y, Nguyen H, Dumpit R, True L, Nelson P, Dong B, Xue W, Birchmeier W, Taketo MM, Xu F, Creighton CJ, Ittmann MM, Xin L. Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms. Cell Stem Cell. 2019 May 2;24(5):753-768.e6. doi: 10.1016/j.stem.2019.03.010. Epub 2019 Apr 11. PubMed PMID: 30982770; PubMed Central PMCID: PMC6548441.

Zhou Y, Dong B, Kim KH, Choi S, Sun Z, Wu N, Wu Y, Scott J, Moore DD. Vitamin D Receptor Activation in Liver Macrophages Protects Against Hepatic Endoplasmic Reticulum Stress in Mice. Hepatology. 2020 Apr;71(4):1453-1466. doi: 10.1002/hep.30887. Epub 2020 Jan 2. PMID: 31381163.

Zou WY, Blutt SE, Zeng XL, Chen MS, Lo YH, Castillo-Azofeifa D, Klein OD, Shroyer NF, Donowitz M, Estes MK. Epithelial WNT Ligands Are Essential Drivers of Intestinal Stem Cell Activation. Cell Rep. 2018 Jan 23;22(4):1003-1015. doi:10.1016/j.celrep.2017.12.093. Epub 2018 Jan 28. PubMed PMID: 29386123; PubMed Central PMCID: PMC5798462.

Heading

Student Awards

Content

Our students are frequently recognized for their achievements with honors and awards. In recent years, these have included:

NRSA F31 Fellowship
Raghav Ramabadran (Mentor: Dr. Margaret Goodell) 
Emmet-Huang Hobbs (Mentor:  Dr. Ben Deneen)
Rachel Curry (Mentor:  Dr. Ben Deneen)

NRSA F30 Fellowship
David Bader (Mentor: Sean McGuire)

F99/K00 - NCI
Yuan-Hung Lo (Mentor: Noah Shroyer)

American Society for Microbiology Science Teaching Fellow 
Laramie Lemon (Mentor: Dr. Alison Bertuch)

FASEB MARC Sponsorship- 2015 Institute on Teaching and Mentoring
Laramie Lemon (Mentor: Dr. Alison Bertuch)