Parmeswaran Diagaradjane, Ph.D
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Parmeswaran Diagaradjane, Ph.D
Assistant Professor
Positions
- Assistant Professor
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Radiation Oncology
Baylor College of Medicine
Houston, US
Addresses
- Attwell Radiation Therapy Center at Smith Clinic (Clinic)
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2525A HOLLY HALL
Houston, TX 77054
United States
Education
- Residency at The UT MD Anderson Cancer Center
- 08/2020 - Houston, Texas United States
- Radiation Oncology Physics
- Graduate Certificate at The UT MD Anderson Cancer Center
- 08/2017 - Houston, Texas United States
- Medical Physics
- Postdoctoral Training at Rice University - Bioengineering
- 03/2006 - Houston, Texas United States
- Bioengineering
- PhD from College of Engineering, Anna University
- 11/2002 - Chennai, India
- Sciences (Medical Physics)
- MSc from College of Engineering, Anna University
- 06/1994 - Chennai, India
- Medical Physics
Certifications
- Therapeutic Medical Physics
- Texas Medical Board
- DABR® -Therapeutic Medical Physics
- American Board of Radiology (ABR)
Professional Development
- The Heart of Leadership
- Course (Participant, 2016)
- Sponsor: The UT MD Anderson Cancer Center
- Project Management Certificate
- Course (Participant, 2015)
- Sponsor: University of Houston
Selected Publications
- Abi Jaoude, J., Kouzy, R., Diagaradjane, P., Taniguchi, C.M "Management of Locally Advanced/Metastatic Disease: Radiation Oncology. In: Bhutani, M.S., Katz, M.H., Maitra, A., Herman, J.M., Wolff, R.A. (eds) Pancreatic Cancer: A Multidisciplinary Approach." Springer, Cham. 2022;107-124.
- Han EY, Diagaradjane P, Luo D, Ding Y, Kalaitzakis G, Zoros E, Zourari K, Boursianis T, Pappas E, Wen Z, Wang J, Briere TM. "Validation of PTV margin for Gamma Knife Icon frameless treatment using a PseudoPatient® Prime anthropomorphic phantom." J Appl Clin Med Phys. 2020;21(9):278-285. Pubmed PMID: 32786141
- Smith DL, Debeb BG, Diagaradjane P, Larson R, Kumar S, Ning J, Lacerda L, Li L, Woodward WA "Prophylactic cranial irradiation reduces the incidence of brain metastasis in a mouse model of metastatic, HER2-positive breast cancer." Genes Cancer.. 2021;12:28-38. Pubmed PMID: 33884104
- Manohar N, Reynoso F, Jayarathna S, Moktan H, Ahmed MF, Diagaradjane P, Krishnan S, Cho SH. "High-sensitivity imaging and quantification of intratumoral distributions of gold nanoparticles using a benchtop x-ray fluorescence imaging system." Opt Lett. 2019;14(21):5314-5317. Pubmed PMID: 31674996
- Debeb BG, Lacerda L, Anfossi S, Diagaradjane P, Chu K, Bambhroliya A, Huo L, Wei C, Larson RA, Wolfe AR, Xu W, Smith DL, Li L, Ivan C, Allen PK, Wu W, Calin GA, Krishnamurthy S, Zhang XH, Buchholz TA, Ueno NT, Reuben JM, Woodward WA. "miR-141-Mediated Regulation of Brain Metastasis From Breast Cancer.." J Natl Cancer Inst.. 2016;108(8):djw026. Pubmed PMID: 27075851
- Manohar N, Reynoso FJ, Diagaradjane P, Krishnan S, Cho SH. "Quantitative imaging of gold nanoparticle distribution in a tumor-bearing mouse using benchtop x-ray fluorescence computed tomography." Sci Rep.. 2016;25(6):22079. Pubmed PMID: 26912068
- Chatterjee DK, Wolfe T, Lee J, Brown AP, Singh PK, Bhattarai SR, Diagaradjane P, Krishnan S. "Convergence of nanotechnology with radiation therapy-insights and implications for clinical translation." Transl Cancer Res.. 2013;2(4):256-268. Pubmed PMID: 25279336
- Puvanakrishnan P, Diagaradjane P, Kazmi SM, Dunn AK, Krishnan S, Tunnell JW. "Narrow band imaging of squamous cell carcinoma tumors using topically delivered anti-EGFR antibody conjugated gold nanorods." Lasers Surg Med. 2012;44(4):310-7. Pubmed PMID: 22415634
- Xie H, Diagaradjane P, Deorukhkar AA, Goins B, Bao A, Phillips WT, Wang Z, Schwartz J, Krishnan S. "Integrin αvβ3-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy." Int J Nanomedicine.. 2011;6:259-69. Pubmed PMID: 21423588
- Chatterjee DK, Diagaradjane P, Krishnan S. "Nanoparticle-mediated hyperthermia in cancer therapy." Ther Deliv.. 2011;2(8):1001-14. Pubmed PMID: 22506095
- Diagaradjane P, Deorukhkar A, Gelovani JG, Maru DM, Krishnan S. "Gadolinium chloride augments tumor-specific imaging of targeted quantum dots in vivo." ACS Nano. 2010;4(7):4131-41. Pubmed PMID: 20586481
- Atkinson RL, Zhang M, Diagaradjane P, Peddibhotla S, Contreras A, Hilsenbeck SG, Woodward WA, Krishnan S, Chang JC, Rosen JM. "Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy." Sci Transl Med.. 2010;2(55):55ra79. Pubmed PMID: 20980696
- Krishnan S, Diagaradjane P, Cho SH. "Nanoparticle-mediated thermal therapy: evolving strategies for prostate cancer therapy." Int J Hyperthermia. 2010;26(8):775-89. Pubmed PMID: 20858069
- Diagaradjane P, Orenstein-Cardona JM, Colón-Casasnovas NE, Deorukhkar A, Shentu S, Kuno N, Schwartz DL, Gelovani JG, Krishnan S. "Imaging epidermal growth factor receptor expression in vivo: pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe." Clin Cancer Res. 2008;14(3):731-41. Pubmed PMID: 18245533
- Diagaradjane P, Shetty A, Wang JC, Elliott AM, Schwartz J, Shentu S, Park HC, Deorukhkar A, Stafford RJ, Cho SH, Tunnell JW, Hazle JD, Krishnan S. "Modulation of in vivo tumor radiation response via gold nanoshell-mediated vascular-focused hyperthermia: characterizing an integrated antihypoxic and localized vascular disrupting targeting strategy." Nano Lett. 2008;8(5):1492-500. Pubmed PMID: 18412402
- Kunnumakkara AB, Diagaradjane P, Guha S, Deorukhkar A, Shentu S, Aggarwal BB, Krishnan S. "Curcumin sensitizes human colorectal cancer xenografts in nude mice to gamma-radiation by targeting nuclear factor-kappaB-regulated gene products." Clin Cancer Res. 2008;14(7):2128-36. Pubmed PMID: 18381954
- Zaman RT, Diagaradjane P, Wang JC, Schwartz J, Rajaram N, Gill-Sharp KL, Cho SH, Rylander HG 3rd, Payne JD, Krishnan S, Tunnell JW. "In Vivo Detection of Gold Nanoshells in Tumors Using Diffuse Optical Spectroscopy." IEEE J Sel Top Quantum Electron.. 2007;13(6):1715-1720. Pubmed PMID: 33859459
- Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B. "Synchronous fluorescence spectroscopic characterization of DMBA-TPA-induced squamous cell carcinoma in mice." J Biomed Opt.. 2006;11(1):014012. Pubmed PMID: 16526889
- Dai T, Diagaradjane P, Yaseen MA, Pikkula BM, Thomsen S, Anvari B. "Laser-induced thermal injury to dermal blood vessels: analysis of wavelength (585 nm vs. 595 nm), cryogen spray cooling, and wound healing effects." Lasers Surg Med.. 2005;37(3):210-8. Pubmed PMID: 16175632
- Diagaradjane P, Madhuri S, Aruna P, Gupta PK, Ganesan S. "In vivo pharmacokinetics of 8-aminolevulinic acid-induced protoporphyrin IX during pre- and post-photodynamic therapy in 7,12-dimethylbenz(a)nthracene-treated skin carcinogenesis in Swiss mice: a comparison by three-compartment model." Photochem Photobiol. 2002;76(1):81-90. Pubmed PMID: 12126311
Intellectual Property
- Method Patent #US9211419B2 (Approved)
- Co Inventors: Sunil Krishnan, Jon Alexander Schwartz, James Chunjay Wang
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