Department of Pediatrics

Grants

Master
Heading

PRIMARY FACULTY

Content

Debra L. Palazzi, M.D, M.Ed.

Title:  Appropriate perioperative antibiotic prophylaxis
Funding Agency:  Agency for Healthcare Research and Quality
Role:  Principal Investigator

Title:  Outpatient antimicrobial stewardship
Funding Agency:  PEW Charitable Trust
Role:  Principal Investigator

Claire E. Bocchini, M.D.

Title:  Addressing caregiver wellbeing and improving child development
Funding Agency:  Episcopal Health Foundation
Role:  Co-Principal Investigator

Title:  Understanding the immune response changes to clinical interventions for Epstein-Barr virus infection prior to lymphoma development in children after organ transplants (UNEARTH)
Funding Agency:  NIH
Role:  Local Co-Principal Investigator

Title:  Comparison of high vs. standard dose influenza vaccine in pediatric solid organ transplant recipients
Funding Agency:  NIH
Role:  Local Co-Investigator

Content

Gail J. Demmler-Harrison, M.D.

Title:  A retrospective follow-up study of the durability of antiviral therapy on long-term hearing and neurodevelopmental outcomes among patients treated for congenital cytomegalovirus infection as infants or toddlers
Funding Agency:  NIH / NID-NIAID-CASG-CPIC
Role:  Local Principal Investigator

Title:  A real-world feasibility study to examine the epidemiology, clinical manifestations, responses to antiviral treatment, and health care utilization and health care costs of congenital cytomegalovirus infection in Texas, USA
Funding Agency:  Moderna, Inc.
Role:  Principal Investigator

Title:  Pregnant people-infant linked longitudinal surveillance, Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET)
Funding Agency:  Cooperative Agreement, Centers for Disease Control and Prevention, Houston Department of Health and Human Services
Role:  Co-Investigator

Title:  Development of a high throughput assay for rapid screening for congenital cytomegalovirus infection using dried blood spots, Phase 2
Funding Agency:  NIH / NIDCD / National Institutes of Health Small Business and Microgen, Inc.
Role:  Sub Award Principal Investigator

Title:  Development of a high throughput assay for rapid screening for congenital cytomegalovirus infection using dried blood spots, Phase 1
Funding Agency:  NIH / NIDCD / National Institutes of Health Small Business and Microgen, Inc.
Role:  Sub Award Principal Investigator

Title:  Identification of biomarkers of audiologic outcomes in congenital CMV infection
Funding Agency:  NIH / NID- NIAID-CASG-CPIC
Role:  Local Principal Investigator

Title:  Health care utilization and health care costs associated with congenital CMV infection and disease
Funding Agency:  Merck Sharpe & Dohme, Inc.
Role:  Contract

Title:  CNS-derived fetal extracellular vesicles for the non-invasive diagnosis of fetal CNS CMV infection
Funding Agency:  NIH
Role:  Co-Investigator

Content

Ankhi Dutta, M.D.

Title:  Ripple effect of leadership: you can be a leader too
Funding Agency:  Center for Research, Innovation and Scholarship in Medical Education, Texas Children’s Hospital
Role:  Principal Investigator

C. Mary Healy, M.D.

Title:  Vaccine and Treatment Evaluation Unit DMID (various studies)
Funding Agency:  NIH
Role:  National Co-Chair (Mpox vaccine trial); Site Principal Investigator (Novavax COVID-19 trial); Co-Investigator (others)

Title:  Adolescent Vaccination Program (AVP)-various studies
Funding Agency:  Cancer Prevention Research Institute of Texas (CPRIT)
Role:  Co-Investigator

Content

Kristina Hulten, Ph.D.

Title:  The United States Pediatric Multicenter Pneumococcal Surveillance Study Group
Funding Agency:  Pfizer, Inc.
Role:  Co-Investigator

Title:  Determination of the utility of Pfizer’s urine antigen test in children under 6 years of age with community-acquired pneumonia in the United States
Funding Agency:  Pfizer, Inc.
Role:  Co-Investigator

Title:  Development of human adaptive immunity to Staphylococcus aureus
Funding Agency:  NIH Sub-award
Role:  Co-Investigator

Title:  A phase 4 study using a test negative design to evaluate the effectiveness of a 20-valent pneumococcal conjugate vaccine against vaccine-type radiologically confirmed community-acquired pneumonia in adults less than or equal to 65 years of age
Funding Agency:  Pfizer, Inc.
Role:  Site PI

Title:  Determination of the utility of Pfizer’s Urine antigen test in children 5 years of age or younger with community acquired pneumonia in the United States [and in Guatemala]
Funding Agency:  Children’s Hospital of Colorado
Role:  Site PI

Title:  Ongoing Evaluation of the Impact of the Introduction of Pneumococcal Conjugate Vaccine (PCV-13) on the Incidence of Parapneumonic Empyema and other Invasive Pneumococcal Disease in Children and Adolescents in Orange County, California
Funding Agency:  Children’s Hospital of Orange County
Role:  Site PI

Content

Sheldon L. Kaplan, M.D.

Title:  The United States Pediatric Multicenter Pneumococcal Surveillance Study Group
Funding Agency:  Pfizer, Inc.
Role:  Principal Investigator

Title:  Determination of the utility of Pfizer’s urine antigen test in children under 6 years of age with community-acquired pneumonia in the United States
Funding Agency:  Pfizer, Inc.
Role:  Principal Investigator

Title:  Development of human adaptive immunity to Staphylococcus aureus
Funding Agency:  NIH Sub-award
Role:  Co-Investigator

Katherine Y. King, M.D., Ph.D.

Title:  Impact of Infection and Inflammation on primitive hematopoiesis
Funding Agency:  NIH / NHLBI
Role:  Principal Investigator

Title:  Modifiable drivers of expansion and malignant transformation from clonal hematopoiesis
Funding Agency:  NIH / NCI
Role:  Project 1 Leader, Administrative Core Co-Lead

Title:  Medical Scientist Training Program
Funding Agency:  NIH / NIGMS
Role:  Co-Principal Investigator

Title:  Diagnosing and studying pathogenic mechanisms of rare diseases
Funding Agency:  Chan Zuckerberg Institute
Role:  Co-Principal Investigator

Content

Katherine P. Lemon, M.D.

Title:  Mechanisms of Corynebacterium-Dolosigranulum interactions that shape human nasal microbiota
Funding Agency:  NIH
Role:  Principal Investigator

Title:  Microbiome discovery and mechanisms to combat antibiotic resistance at mucosal surfaces
Funding Agency:  NIH
Role:  Multiple Principal Investigator (Britton, Lemon, Maresso, Patras)

Jonathon C. McNeil, M.D.

Title:  The impact of healthcare exposure on colonization with antiseptic tolerant staphylococci in children
Funding Agency:  Agency for Healthcare Research and Quality
Role:  Principal Investigator

Title:  Development of human adaptive immunity to Staphylococcus aureus
Funding Agency:  NIH / NIAID
Role:  Co-Investigator  (PI: Bubeck-Wardernburg, Fritz)

Content

Flor D. Muñoz-Rivas, M.D.

Title:  Vaccine and Treatment Evaluation Units (VTEUs)
Funding Agency:  NIH / NIAID
Role:  Co-Investigator

Title:    A prospective study of acute flaccid myelitis (AFM) natural history, risk factors and pathogenic mechanisms
Funding Agency:  NIH / NIAID
Role:  Site Principal Investigator

Title:  Zika natural history study in Guatemala
Funding Agency:  NIH
Role:  Principal Investigator

Title:  An integrated one health approach to detect and respond to emerging disease threats in high-risk region of Central America
Funding Agency:  NIH / CDC
Role:  Co-Investigator

Title:  Surveillance for vaccine-preventable disease in children
Funding Agency:  CDC
Role:  Co-Investigator

Title:  A master phase 1/2/3 protocol to investigate the safety, tolerability, and immunogenicity of bivalent BNT162B2 RNA-based vaccine candidate(s) in healthy children
Funding Agency:  Pfizer, Inc.
Role:  Principal Investigator

Title:  A phase 1, open-label dose-finding study to evaluate safety, tolerability, and immunogenicity and phase 2/3 placebo controlled, observer-blinded safety, tolerability, and immunogenicity study of SARS-CoV-2RNA vaccine candidate against COVID-19 in healthy children and young adults
Funding Agency:  Pfizer, Inc.
Role:  Principal Investigator

Title:  A phase 2b, open-label study to evaluate the safety, tolerability, and immunogenicity of vaccine candidate BNT162b2 in immunocompromised participants ≥2 years of age
Funding Agency:  Pfizer, Inc.
Role:  Principal Investigator

Title:  A phase 2/3 single-arm, open-label study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of remdesivir (GD-5734) in participants from birth to <18 Years of age with COVID-19
Funding Agency:  Gilead Sciences
Role:  Principal Investigator

Title:  Comparison of high vs. standard dose influenza vaccine in pediatric solid organ transplant recipients
Funding Agency:  NIH / NIAID
Role:  Site Principal Investigator

Content

Erin Nicholson, M.D.

Title:  A phase 2/3, two-part, open-label, dose escalation, age de-escalation and randomized, observer-blind, placebo-controlled expansion study to evaluate the safety, tolerability, reactogenicity, and effectiveness of mRNA-1273 SARS-CoV-2 vaccine in healthy children 6 months to < 12 years of age
Funding Agency:  NIH / NIAID / VTEU
Role:  Principal Investigator

Title:  Human biomimetics for mucosal infections
Funding Agency:  NIH/NIAID
Role:  Sub-Investigator

Title:  Observation, prospective cohort study of the immunogenicity and safety of SARS-CoV-2 vaccines administered during pregnancy or post-partum and evaluation of antibody transfer and durability in infants
Funding Agency:  NIH / NIAID / VTEU
Role:  Sub-Investigator

Title:  A phase 1/2a trial of the safety, tolerability, and immunogenicity of PIV5-vectored RSV vaccine (BLB-201) in RSV seronegative and seropositive infants and children
Funding Agency:  Blue Lake Biotechnology, Inc.
Role:  Site Principal Investigator

Title:  A phase 2 randomized, open-label, multisite trial to inform public health strategies involving the use of MVA-BN vaccine for Mpox
Funding Agency:  NIH / NIAID / VTEU
Role:  Sub-Investigator

Title:  Pandemic Threat Technology Center
Funding Agency:  BCM / Philanthropic Funding
Role:  Co-Director

Margaret G. Taylor, M.D.

Title:  A proposal for outpatient antimicrobial stewardship with the Texas Children’s Health Plan
Funding Agency:  Pew Charitable Trusts
Role:  Principal Investigator