In higher organisms, genes are persistently regulated to achieve cellular differentiation and multicellularity. Dysregulation of this regulatory system is common in many diseases. The pharmacological manipulation of this system is a potentially powerful approach to the treatment of disease. CPSB research focuses on the detailed biochemical mechanisms of gene regulation at the transcriptional and translational levels and how to effectively manipulate these systems therapeutically.
Faculty Profiles: Gene Regulation, Chromatin and Epigenetics
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