Clinical Studies for Genetic and Rare Diseases
View a list of clinical trials by topic:
Find out more about our faculty's research projects by visiting their bios. You can find links to our faculty's bios by visiting the listings on Our Team.
Knockout Mouse Project
Baylor College of Medicine leads one of three groups that have received funding from the NIH to build a better mouse model that will enable scientists to identify the function of important protein-coding genes in the mammalian genome.
Heritable Disorders of Connective Tissue Research
The Pamela and David Ott Center of Excellence in Heritable Disorders of Connective Tissue and Ehlers-Danlos Syndrome at Baylor College of Medicine was established to pursue cutting-edge research in the field of heritable connective tissue disorders.
Undiagnosed Diseases Center
Baylor College of Medicine Undiagnosed Diseases Center is dedicated to taking a multidisciplinary approach to diagnosing patients who remain undiagnosed after extensive clinical testing or those who have extreme, unusual presentations of known conditions.
Center for Precision Medicine Models
Baylor College of Medicine Center for Precision Medicine Models supports researchers, clinicians, genetic counselors, patients and support organizations in the development and study of precision animal models of human-disease-associated genetic variation.
The Clinical Genome Resource, or ClinGen, is a National Institutes of Health-funded resource dedicated to building an authoritative central resource that defines the clinical relevance of genes and variants for use in precision medicine and research. A multidisciplinary team from Baylor and Stanford has led one of the consortium awards since 2013 and is now working on phase three of the project.
Baylor is one of the five research centers that are a part of the GREGoR Consortium. The consortium, funded through the NHGRI, is aimed at significantly increasing the proportion of Mendelian disorders with an identified genetic cause through enhanced data sharing, collaboration, and increasing the application of new technologies, sequencing strategies and analytical approaches.
Rare Disease Clinical Research Network
Baylor is a member of The Rare Diseases Clinical Research Network through its participation in the following consortiums: Brittle Bone Disorders Consortium, Urea Cycle Disorders Consortium, Frontiers in Congenital Disorders of Glycosylation, and the North American Mitochondrial Disease Consortium.
Department Research Cores
The research cores in the Department of Molecular and Human Genetics complement the Baylor College of Medicine Advanced Technology Cores by providing services not available via the ATC.