Healthcare: Weight Loss and Metabolic Center

Single Anastomosis Duodeno-Ileostomy Bypass with Sleeve Gastrectomy (SADI-S)

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Scott Holmes
Illustration of the SADI-S procedure

This operation consists of 2 parts:

  1. A part of the stomach is removed to create a narrow tube, much like the sleeve gastrectomy.
  2. A large part of the intestine is bypassed (as in the Duodenal Switch), but in this case, only one connection is made between the duodenum and the small intestine.

This operation is very similar to the Duodenal Switch but, in this case, there is only one connection with the small intestine and the common channel is longer, so that it is less likely to cause malabsorption. As in the other metabolic operations, it results in significant reduction of appetite and reduces absorption of calories from the small intestine. It also has a strong impact on metabolic hormones and improving health conditions.



  • Greater weight loss than sleeve gastrectomy or Roux-en-Y gastric bypass
  • Reduces the absorption of fat by 70%
  • Causes favorable changes in gut hormones to reduce appetite and improve fullness
  • Is effective against diabetes 


  • Increased risk of nutritional deficiencies, but less than Roux-en-Y gastric bypass
  • Patients should be fully compliant with nutritional supplements and follow up appointments
  • Frequent bowel movements may occur if a healthy diet is not followed