Positions
- Assistant Professor
-
Molec. Physiology/Hamilton
Baylor College of Medicine
Houston, TX US
Addresses
- BCM-MD Anderson Hall (Lab)
-
Room: BCMA-400B
Houston, TX 77030
United States
Education
- PhD from Korea University
- 02/2004 - Seoul, South Korea
Professional Interests
- Ca2+ channel-mediated events in skeletal muscle and whole body metabolism
Websites
Selected Publications
- Carlo Manno, Lourdes Figueroa, Leandro Royer, Sandrine Pouvreau, Chang Seok Lee et. al. "Altered Ca2+ concentration, permeability and buffering in the myofiber Ca2+ store of a mouse model of malignant hyperthermia." Journal of Physiology. 2013 Sep 15;591(18)
- Dimitra K. Georgiou*, Adan Dagnino-Acosta*, Chang Seok Lee*, Deric M. Griffin, Hui Wang, William R. Lagor, Robia G. Pautler, Robert T. Dirksen and Susan L. Hamilton. "Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism." J. Biol. Chem.. 2015 Aug;
- Chang Seok Lee1, Adan Dagnino-Acosta1, Viktor Yarotskyy2, Amy Hanna1, Alla Lyfenko2, Mark Knoblauch1, Dimitra K. Georgiou1, Ross A. Poché1, Michael W. Swank1, Cheng Long1, Iskander I. Ismailov1, Johanna Lanner1, Ted Tran1, KeKe Dong et. al. "Ca2+ Permeation and/or Binding to CaV1.1 Fine-Tunes Skeletal Muscle Ca2+ Signaling to Sustain Muscle Function.." Skeletal Muscle. 2015 Jan 29;5(4)
- Chang Seok Lee1*, Dimitra K.Georgiou1*, Adan Dagnino-Acosta1*, Jianjun Xu1,5, Iskander I. Ismailov1,6, Mark Knoblauch1, Tanner O. Monroe1, RuiRui Ji1, Amy D. Hanna et. al. "Ligands for FKBP12 Increase Ca2+ Influx and Protein Synthesis to Improve Skeletal Muscle Function." J. Biol. Chem.. 2014 Sep 12;289(37)
- Jae-Sung Yi1, Jun-sub Park1, Young-Mi Ham1, Nga Nguyen1, Na-Rae Lee1, Jin Hong1, Bong-Woo Kim1, Hyun Lee1, Chang-Seok Lee et. al. "MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signaling." Nature Communications. 2013 Aug 22;
- Johanna T Lanner*, Dimitra K Georgiou*, Adan Dagnino-Acosta, Alina Ainbinder, Qing Cheng, Aditya D Joshi, Zanwen Chen, Viktor Yarotskyy, Joshua M Oakes, Chang Seok Lee et. al. "AICAR prevents heat-induced sudden death in RyR1 mutant mice independent of AMPK activation." Nat. Med.. 2012 Feb;18(2)
- Chang Seok Lee1*, Jae-Sung Yi1*, Soon-Young Jung1, Bong-Woo Kim1, Na-Rae Lee1, Hyo-Jung Choo1, Soon-Young Jang1, Jikhyun Han1, Sung-Gil Chi1, Minseon Park2, Jae-Ho Lee2, and Young-Gyu Ko "TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1." Cell Death Diff.. 2010 Aug;17(8)
Projects
- Regulation of Apoptosis by Endoplasmic/Sarcoplasmic Reticulum Ca2+ Stores: Role in Central Core Disease
- Baylor College of Medicine (01/2012 - present)
- Molecular Physiology and Biophysics
- Project on going
- A novel mechanism of brown adipogenesis through Ca2+ events
- Baylor College of Medicine (01/2015 - present)
- Molecular Physiology and Biophysics
- On going Project
Memberships
- American Association for the Advancement of Science (AAAS)
- Regular Member (08/2015 - 08/2016)
- Biophysical Society
- Postdoc member (03/2011 - 03/2012)
Skills
- Ca2+ signaling pathways
- Muscle Fiber typing
- Muscle Metabolisms
- Brown adipose precursor cell culture
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