Email

Jin.Xu@bcm.edu

Positions

Director of Research and Business Development

Jan and Dan Duncan Neurological Research Institute
Baylor College of Medicine

Addresses

1250 MOURSUND STREET (Office)

Room: DNRI-1370.04
Houston, TX 77030
United States
Phone: (832) 824-8118

Education

Postdoctoral Fellowship at Harvard Medical School, Boston Children's Hospital

Boston, Massachusetts United States

Molecular Neuroscience

PhD from Tulane University

New Orleans, Louisiana

Molecular Cellular Biology

Professional Interests

• Therapeutic development for neurological diseases

Professional Statement

Support and promote the translational research and therapeutic development activities at the Jan and Dan Duncan Neurological Research Institute

Selected Publications

• Xu W, Bao P, Jiang X, Wang H, Qin M, Wang R, Wang T, Yang Y, Lorenzini I, Liao L, Sattler R, Xu J "Reactivation of Nonsense-Mediated mRNA Decay Protects Against C9orf72 Dipeptide-Repeat Neurotoxicity." Brain. 2019 May 1;142(5):1349-1364. Pubmed PMID: 30938419
• Xu W, Xu J "C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in Drosophila Glutamatergic Neurons." J Neurosci.. 2018 Aug;38(35):7741-7752. Pubmed PMID: 30037833
• Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA. "The Parkinson's Disease-Associated DJ-1 Protein Is a Transcriptional Co-Activator That Protects Against Neuronal Apoptosis." Hum Mol Genet.. 2005 May;14(9):1231-41. Pubmed PMID: 15790595
• Xu J, Kao SY, Lee FJ, Song W, Jin LW, Yankner BA. "Dopamine-dependent Neurotoxicity of Alpha-Synuclein: A Mechanism for Selective Neurodegeneration in Parkinson Disease." Nat Med.. 2002 Jun;8(6):600-6. Pubmed PMID: 12042811