Positions

Assistant Professor

Molecular and Cellular Biology
Baylor College of Medicine
Houston, TX US

Member and Duncan Faculty Scholar

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, TX United States

Education

PhD from The University of Alabama at Birmingham

12/2008 - Birmingham, Alabama United States

Cell Biology

MS from The University of Alabama at Birmingham

05/2003 - Birmingham, Alabama United States

Forensic Science

BS from Virginia Tech

05/2001 - Blacksburg, Virginia United States

Biology/Biotechnology, Chemistry

Professional Interests

• Cancer Biology
• Cell and Developmental Biology
• Cellular Heterogeneity in Breast Cancer Progression and Metastasis
• Wnt Signaling

Professional Statement

The Roarty Laboratory investigates the molecular mechanisms regulating the cellular makeup within tumors and how cell populations communicate during breast cancer progression. Our work spans the spectrum of cell, developmental, and cancer biology. We study how spatiotemporal cues coordinate the identity and multicellular movement of epithelial cells during morphogenesis within the normal breast, and how developmental signals, often co-opted during cancer progression, direct the invasion and spread of tumor cells to distant organs during breast cancer metastasis.

Websites

Selected Publications

• Roarty K, Pfefferle AD, Creighton CJ, Perou CM, Rosen JM. "Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression.." Oncogene. 2017 Jun 26; Pubmed PMID: 28650466
• Roarty K, Shore AN, Creighton C, and Rosen JM "Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium." J Cell Biol. 2015 Feb 2;208(3):351-366. Pubmed PMID: 25624393
• Sreekumar A, Roarty K, Rosen JM. "The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes.." Endocr Relat Cancer. 2016; Pubmed PMID: 26206777
• "Complete list of published work on NCBI." ;