Department of Pediatrics

Translational Research in Resource-Limited Settings


In collaboration with the Aga Khan University, Karachi, Pakistan, we are developing a research protocol to study the utility of urinary nitric oxide as a biomarker for neonatal sepsis in community-based settings of a developing country. The ultimate significance of this would be in the development and validation of simple, inexpensive urinary test strips for nitric oxide metabolites. These will be effectively utilized by low-literacy, minimally trained community health workers to screen newborn babies in the community at high risk for severe sepsis, so that medical intervention can be sought earlier.

Asad Mian, M.D., Ph.D.