You will need to keep in close contact with your primary care doctor regarding any long-term medications you are currently taking. For medications that need to be continued, the vast majority can be swallowed, absorbed, and work the same as before weight loss surgery. Your doctor will determine whether certain medications can be discontinued after weight loss surgery. Change in dosage may be required with weight loss but will need to be discussed with your primary care doctor.
Two classes of medications that should be discussed during your consultation with your surgeon are diuretics (water pills) and NSAIDs (most over-the-counter pain medicines). In the case of patients with Roux-en-Y gastric bypass, NSAIDs (ibuprofen, naproxen, etc.) may create ulcers in the small pouch or the attached bowel. Diuretic medications promote urine formation which might lead to dehydration after bariatric surgery.