Sandra A Darilek, M.S., C.G.C.
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Sandra A Darilek, M.S., C.G.C.
Associate Professor, Co-Manager Prenatal Genetics Service
Phone
Phone
Positions
- Associate Professor, Co-Manager Prenatal Genetics Service
-
Mol. & Human Gen./Clinic. Prgm
Baylor College of Medicine
Houston, TX US
Education
- MS from University Of Texas At Houston Graduate School Of Biomedical Sciences
- 05/2003 - Houston, Texas United States
- Genetic Counseling
- BS from Texas A&M University
- 12/2000 - College Station, Texas United States
- Genetics
Certifications
- Certified Genetic Counselor
- #2005063
- American Board of Genetic Counseling
- Licensed Genetic Counselor
- #GC000615 (02/28/2021 - 02/28/2024)
- State of California
- Licensed Genetic Counselor
- #325729 (07/01/2022 - 06/30/2023)
- State of Louisiana
- Licensed Genetic Counselor
- #GC343 (10/01/2022 - 10/01/2023)
- State of Alabama
- Licensed Genetic Counselor
- #LGC-0350 (09/22/2022 - 09/22/2024)
- State of Arkansas
- Licensed Genetic Counselor
- #LGC0587 (02/12/2023 - 02/27/2025)
- State of Oklahoma
- Licensed Genetic Counselor
- #GC2023-0117 (08/14/2023 - 03/01/2025)
- State of New Mexico
Honors & Awards
- Secretary/Treasurer
- National Society of Genetic Counselors (01/2015 - 12/2015)
- Secretary/Treasurer Elect
- National Society of Genetic Counselors (01/2014 - 12/2014)
- 2022 Outstanding Supervisor Award
- Association of Genetic Counseling Program Directors
- 2019 Women of Excellence Award
- Baylor College of Medicine
- 2017 Code Talker Nominee
- Genome Magazine
- 2013 Outstanding Alumni Award
- University of Texas-Houston Genetic Counseling Program
Professional Interests
- Prenatal Genetic Counseling
- Infertility and Preimplantation Genetic Counseling
- Prenatal testing/screening
- Preimplantation genetic testing (PGT, PGT-A, PGT-M, PGT-SR)
Professional Statement
I am dedicated to providing patients with the information and care they need to understand their genetic risks, navigate their genetic testing options, and make use of the information they gain through this process. My areas of interest are prenatal genetics, preimplantation genetics and infertility.Websites
Selected Publications
- Cooper ML, Darilek S, Wun WS, Angus SC, Mensing DE, Pursley AN, Dunn RC, Grunert GM, Cheung SW "A retrospective study of preimplantation embryos diagnosed with monosomy by fluorescence in situ hybridization (FISH).." Cytogenet. Genome Res.. 2006;114(41337):359-66. Pubmed PMID: 16954679
- Alford RL, Darilek SA "Basic medical genetics for the otolaryngologist.." Adv. Otorhinolaryngol.. 2011;70:41554. Pubmed PMID: 21358179
- Van den Veyver IB, Patel A, Shaw CA, Pursley AN, Kang SH, Simovich MJ, Ward PA, Darilek S, Johnson A, Neill SE, Bi W, White LD, Eng CM, Lupski JR, Cheung SW, Beaudet AL "Clinical use of array comparative genomic hybridization (aCGH) for prenatal diagnosis in 300 cases.." Prenat. Diagn.. 2009 Jan;29(1):29-39. Pubmed PMID: 19012303
- Tang HY, Fang P, Ward PA, Schmitt E, Darilek S, Manolidis S, Oghalai JS, Roa BB, Alford RL "DNA sequence analysis of GJB2, encoding connexin 26: observations from a population of hearing impaired cases and variable carrier rates, complex genotypes, and ethnic stratification of alleles among controls.." Am. J. Med. Genet. A. 2006 Nov 15;140(22):2401-15. Pubmed PMID: 17041943
- Darilek S, Wicklund C, Novy D, Scott A, Gambello M, Johnston D, Hecht J "Hereditary multiple exostosis and pain.." J Pediatr Orthop.;25(3):369-76. Pubmed PMID: 15832158
- Tang HY, Basehore MJ, Blakey GL, Darilek S, Oghalai JS, Roa BB, Fang P, Alford RL "Infrequency of two deletion mutations at the DFNB1 locus in patients and controls.." Am. J. Med. Genet. A. 2008 Apr 1;146(7):934-6. Pubmed PMID: 18324688
- Brandt AC, Tschirgi ML, Ready KJ, Sun C, Darilek S, Hecht J, Arun BK, Lu KH "Knowledge, attitudes, and clinical experience of physicians regarding preimplantation genetic diagnosis for hereditary cancer predisposition syndromes.." Fam. Cancer. 2010 Sep;9(3):479-87. Pubmed PMID: 20431955
- Darilek S, Ward P, Pursley A, Plunkett K, Furman P, Magoulas P, Patel A, Cheung SW, Eng CM "Pre- and postnatal genetic testing by array-comparative genomic hybridization: genetic counseling perspectives.." Genet. Med.. 2008 Jan;10(1):13-8. Pubmed PMID: 18197052
- Sahoo T, Cheung SW, Ward P, Darilek S, Patel A, del Gaudio D, Kang SH, Lalani SR, Li J, McAdoo S, Burke A, Shaw CA, Stankiewicz P, Chinault AC, Van den Veyver IB, Roa BB, Beaudet AL, Eng CM "Prenatal diagnosis of chromosomal abnormalities using array-based comparative genomic hybridization.." Genet. Med.. 2006 Nov;8(11):719-27. Pubmed PMID: 17108764
- Allyse, M, Aypar U, Bonhomme N, Darilek S, Dougherty M, Farrell R, Grody W, Highsmith WE, Michie M, Nunes M, Otto L, Pabst R, Palomaki G, Runke C, Sharp RR, Skotko B, Stoll K, Wick M. "Offering prenatal screening in the age of genomic medicine: a practical guide." J Womens HEalth (Larchmt). 2017 Apr 7; Pubmed PMID: 28388340
- Scott DA, Hernandez-Garcia A, Azamian MS, Jordan VK, Kim BJ, Starkovich M, Zhang J, Wong LJ, Darilek SA, Breman AM, Yang Y, Lupski JR, Jiwani AK, Das B, Lalani SR, Iglesias AD, Rosenfeld JA, Xia F "Congenital heart defect and left ventricular non-compaction in males with loss-of-function variants in NONO.." J Med Genet. 2017 Jan;54(1):47-53. Pubmed PMID: 27550220
- McGuire A, Moore Q, Majumder M, Walkiewicz M, Eng CM, Belmont JW, Nassef S, Darilek S, Rutherford K, Pereira S, Scherer SE, Sutton VR, Wolf D, Gibbs RA, Kahn R, Sanchez LA "The ethics of conducting molecular autopsies in the cases of sudden death in the young.." Genome Res. 2016 Sep;26(9):1165-9. Pubmed PMID: 27412853
- Kohn TP, Kohn JR, Darilek S, Ramasamy R, Lipshultz L "Genetic counseling for men with recurrent pregnancy loss or recurrent implantation failure due to abnormal sperm chromosomal aneuploidy." J Assist Reprod Genetic. 2016 May;33(5):571-6. Pubmed PMID: 27020275
- Mayes S, Hashmi S, Turrentine M, Darilek S, Friel L, Czerwinski J "Obstetrician and gynecologist utilization of the NIPT expanded testing option." Am J Perinatol Rep. 2016;6:e18-e24. Pubmed PMID: 26929864
- Westerfield L, Darilek S, Van den Veyber IB "Counseling challenges with variants of uncertain significance and incidental findings in prenatal genetic screening and diagnosis." J Clin Med. 2014;3(3):1018-1032. Pubmed PMID: 26237491
- Tany H-Y, Fang P, Lin JW, Darilek S, Osborne BT, Haymond JA, Manolidis S, Roa BB, Oghalai JS, Alford RL "DNA sequence analysis and genotype-phenotype assessment in 71 patients with syndromic hearing loss or auditory neuropathy." BMJ Open. 2015;5 Pubmed PMID: 25991456
- Dungan JS, Klugman S, Darilek S, Malinowski J, Akkari YMN, Monaghan KG, Erwin A, Best RG, ACMG Board of Directors "Noninvasive prenatal screening (NIPS) for fetal chromosome abnormalities in a general-risk population: An evidence-based clinical guideline of the American College of Medical Genetics and Genomics (ACMG)." 2023 Feb;25(2):100336. Pubmed PMID: 36524989
- • Manor J, Dinu D, Azamian MS, Bi W, Darilek S, Lalani SR "A rare description of pure partial trisomy of 16q12.2q24.3 and review of the literature." 2021 Oct;185(10):2903-2912. Pubmed PMID: 34061437
- • Alkhunaizi E, Shuster S, Shannon P, Siu VM, Darilek S, Mohila CA, Boissel S, Ellezam B, Fallet-Bianco C, Laberge AM, Zandberg J, Injeyan M, Hazrati LN, Hamdan F, Chitayat D "Homozygous/compound heterozygote RYR1 gene variants: Expanding the clinical spectrum." ; Pubmed PMID: 30652412
- "The sixth international RASopathies symposium: Precision medicine-From promise to practice.." ; Pubmed PMID: 31825160
- "Phenotypic expansion in DDX3X – a common cause of intellectual disability in females." ; Pubmed PMID: 30349862
- "Attitudes Toward and Uptake of Prenatal Genetic Screening and Testing in Twin Pregnancies." ; Pubmed PMID: 29525932
- "Genesurance Counseling: Patient Perspectives." ; Pubmed PMID: 29350312
Memberships
- National Society of Genetic Counselors (NSGC)
- (08/2002)
- Texas Society of Genetic Counselors
- (05/2006)
- American College of Medical Genetics and Genomics
- Member
- American Society of Reproductive Medicine
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