Email

shixiah@bcm.edu

Positions

Associate Professor

Mol & Cell Biology
Baylor College of Medicine

Director, Antibody-Based Proteomics Core

Advanced Technology Cores
Baylor College of Medicine
Houston, Texas United States

Associate Professor

Education, Innovation & Technology
Baylor College of Medicine

Faculty Senator

Baylor College of Medicine

Chair, Research Subcommittee

Inclusion and Excellence Council
Baylor College of Medicine

Member

Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine

DEI Council Member

Association of Biomolecular Resource Facilities

Education

PhD from Michigan State University

East Lansing, Michigan United States

Genetics

Postdoctoral Fellowship at National Cancer Institute

Bethesda, Maryland United States

Postdoctoral Fellowship at Memorial Sloan-Kettering Cancer Center

New York, New York United States

MS from Yangzhou University

Yangzhou, Jiangsu China, People's Rep

Infectious Disease & Preventive Veterinary Medicine

BS from Hunan Agricultural University

Changsha, Hunan China, People's Rep

Veterinary Medicine

Professional Statement

Developing high-throughput antibody-based proteomic platforms for protein biomarker discovery and validation, especially for low abundance regulatory proteins and their activation states such as phosphorylation and histone translational modifications.
Combining my advance technology expertise and passion in education to build biotechnology education programs with a focus on diversity and inclusion.

Websites

Selected Publications

• Huang S, Li Y, Chen Y, Podsypanina K, Chamorro M, Olshen AB, Desai KV, Tann A, Petersen D, Green JE, Varmus HE "Changes in gene expression during the development of mammary tumors in MMTV-Wnt-1 transgenic mice.." Genome Biol..2005;6(10):R84. Pubmed PMID: 16207355
• Huang S, Flanders KC, Roberts AB "Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues.." Gene.2000/November27;258(41276):43-53. Pubmed PMID: 11111041
• Li Y, Welm B, Podsypanina K, Huang S, Chamorro M, Zhang X, Rowlands T, Egeblad M, Cowin P, Werb Z, Tan LK, Rosen JM, Varmus HE "Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells.." Proc. Natl. Acad. Sci. U.S.A..2003/December23;100(26):15853-8. Pubmed PMID: 14668450
• Lu, H.-Y., Xiong, j., Perera, D. N., Rajapakshe, K., Wang, X., Costello M., Holloway K. R., Ramos, C., Grimm, S. L., Wulfkuhle, J., Coarfa, C., Edwards, D. P., Zhu, M. X., and Huang, S. "High-throughput Evaluation of Metabolic Activities Using Reverse Phase Protein Array (RPPA) Technology." Book chapter in: Tong, Q., 1st ed. Neuronal Signaling in Metabolism.2021/June;1st Edition:25.

Projects

Program Director: Baylor College of Medicine Biotechnology Research Incubator for TEachers (BCM-BRITE)

Baylor College of Medicine

Houston, Texas

To educate the next generation thinkers and problem solvers in secondary school, science teachers’ passion and understanding in bioscience research and technology are critically important. The objective of BCM-BRITE program is a professional development experience for passionate educators. Teachers are paired with scientists for a scientific immersion experience, translating into high-quality classroom experiences for their students and sustaining STEMM (Science Technology Engineering, Mathematics, and Medicine) education at a rigorous level. Goals: 1. Improve the quality of STEMM education through providing intensive two-weeks hands-on technology-research immersion opportunities as a professional training program to middle/high school teachers. 2) Enhance teachers’ understanding of rigorous research and biotechnology literacy in STEMM. 3) Facilitate students’ STEMM education through evaluation and following-up with BCM-BRITE teachers’ success and their lesson plans and with scientist mentor's visits to their classrooms/career fairs to share careers in STEMM and scientific exploration.