Thomas Eugene Lloyd, M.D., Ph.D.
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Thomas Eugene Lloyd, M.D., Ph.D.
Chair
Positions
- Chair
-
Neurology
Baylor College of Medicine
Houston, Texas United States
Education
- Fellowship at Johns Hopkins Hospital
- Baltimore, Md.
- Neuromuscular Medicine
- Residency at Johns Hopkins Hospital
- Baltimore, Md.
- Neurology
- Internship at Johns Hopkins Hospital
- Baltimore, Md.
- Internal Medicine
- MD from Baylor College of Medicine
- Houston, Texas United States
- Graduated with Honors
- PhD from Baylor College of Medicine
- Houston, Texas United States
- Molecular and Cell Biology
- BA from Rice University
- Houston, Texas United States
- Chemistry and Biochemistry
Certifications
- Neurology
- American Board of Psychiatry and Neurology
Websites
Comprehensive list of publications and presentations
Selected Publications
- Lloyd TE, Atkinson R, Wu MN, Zhou Y, Pennetta G, Bellen HJ "Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila." Cell. 2002;108(2):261-9. Pubmed PMID: 11832215
- Lloyd TE, Machamer J, O'Hara K, Kim JH, Collins SE, Wong MY, et al. "The p150(Glued) CAP-Gly domain regulates initiation of retrograde transport at synaptic termini." Neuron. 2012;74(2):344-60. Pubmed PMID: 22542187
- Lloyd TE, Mammen AL, Amato AA, Weiss MD, Needham M, Greenberg SA "Evaluation and construction of diagnostic criteria for inclusion body myositis." Neurology. 2014;83(5):426-33. Pubmed PMID: 24975859
- Zhang K, Donnelly CJ, Haeusler AR, Grima JC, Machamer JB, Steinwald P, et al. "The C9ORF72 repeat expansion disrupts nucleocytoplasmic transport." Nature. 2015;525(7567):56-61. Pubmed PMID: 26308891
- Zhang K, Daigle JG, Cunningham KM, Coyne AN, Ruan K, Grima JC, et al. "Stress granule assembly disrupts nucleocytoplasmic transport." Cell. 2018;173(4):958-71 e17. Pubmed PMID: 29628143
- Vogler TO, Wheeler JR, Nguyen ED, Hughes MP, Britson KA, Lester E, et al. "TDP-43 and RNA form amyloid-like myo-granules in regenerating muscle." Nature. 2018;563(7732):508-13. Pubmed PMID: 30464263
- Cunningham KM, Maulding K, Ruan K, Senturk M, Grima JC, Sung H, et al. "TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS." elife. 2020;9 Pubmed PMID: 33300868
- Woolums BM, McCray BA, Sung H, Tabuchi M, Sullivan JM, Ruppell KT, et al. "TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca(2)." Nat Commun. 2020;11(1):2679. Pubmed PMID: 32471994
- Britson KA, Ling JP, Braunstein KE, Montagne JM, Kastenschmidt JM, Wilson A, et al. "Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis." Sci Transl Med. 2022;14(628):eabi9196. Pubmed PMID: 35044790
- Dubey SK, Maulding K, Sung H, Lloyd TE "Nucleoporins are degraded via upregulation of ESCRT-III/Vps4 complex in Drosophila models of C9-ALS/FTD." Cell Rep. 2022;40(12):111379. Pubmed PMID: 36130523
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