Gene Vector Core Publications


Deng S, Oka K. Adeno-Associated Virus as Gene Delivery Vehicle into the Retina. Methods Mol Biol 2020; 2092: 77-90. PMID: 31786783,

Ogawa N, Terashima T, Oka K, Chan L, Kojima H. Gene therapy for neuropathic pain using dorsal root ganglion-targeted helper-dependent adenoviral vectors with GAD67 expression. Pain Rep 2018; 3: e695. PMID: 30706038,  PMC6344132.

Ito A, Hong C, Oka K, Salazar JV, Diehl C, Witztum JL, Diaz M, Castrillo A, Bensinger SJ, Chan L, Tontonoz P. Cholesterol Accumulation in CD11c(+) Immune Cells Is a Causal and Targetable Factor in Autoimmune Disease. Immunity 2016; 45: 1311-1326. PMID: 28002731,  PMC5181791.

Chen Q, Takahashi Y, Oka K, Ma JX. Functional Differences of Very-Low-Density Lipoprotein Receptor Splice Variants in Regulating Wnt Signaling. Mol Cell Biol 2016; 36: 2645-2654. PMID: 27528615,  PMC5038150.

Son SH, Goo YH, Choi M, Saha PK, Oka K, Chan LC, Paul A. Enhanced atheroprotection and lesion remodelling by targeting the foam cell and increasing plasma cholesterol acceptors. Cardiovasc Res 2016; 109: 294-304. PMID: 26487692,  PMC4724936.

Li R, Buras E, Lee J, Liu R, Liu V, Espiritu C, Ozer K, Thompson B, Nally L, Yuan G, Oka K, Chang B, Samson S, Yechoor V, Chan L. Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice. Gene Ther 2015; 22: 876-882. PMID: 26172077,  PMC4636470.

Willecke F, Yuan C, Oka K, Chan L, Hu Y, Barnhart S, Bornfeldt KE, Goldberg IJ, Fisher EA. Effects of High Fat Feeding and Diabetes on Regression of Atherosclerosis Induced by Low-Density Lipoprotein Receptor Gene Therapy in LDL Receptor-Deficient Mice. PLoS One 2015; 10: e0128996. PMID: 26046657,  PMC4457481.

Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice. Diabetes 2015; 64: 529-540. PMID: 25332429,  PMC4303975.

Oka K, Mullins CE, Kushwaha RS, Leen AM, Chan L. Gene therapy for rhesus monkeys heterozygous for LDL receptor deficiency by balloon catheter hepatic delivery of helper-dependent adenoviral vector. Gene Ther 2015; 22: 87-95. PMID: 25231173,  PMC4289097.