Research

Gene Vector Core Publications

Master
Content

Henrickson A, Ding X, Seal A, Qu Z, Tomlinson L, Forsey J, Gradinaru V, Oka K, Bemeler B. Characterization and quantification of adeno-associated virus capsid-loading states by multi-wavelength analytical ultracentrifugation with UltraScan. Nanomedicine (Lond). 2023 Sep;18(22):1519-1534. PMID: 37877696.

Kulkarni A, Seal A, Sonnet C, Oka K. Streamlined Adeno-Associated Virus Production Using Suspension HEK293T Cells. Bio-protocol 2024; 14(3): e4931.

Seal A, Moinzadeh A, Oka K, Purchel A, Chen M. Characterizing lentiviral and gammaretroviral vectors by batch DLS and FFF-MALS. AN9010, 2022. Wyatt Technology.

Park KW, Wood CA, Li J, Taylor BC, Oh S, Young NL, Jankowsky JL. Gene therapy using Abeta variants for amyloid reduction. Mol Ther 2021; 29: 2294-2307. PMID: 33647457, PMC8261072.

Fan S, Xu Y, Lu Y, Jiang Z, Li H, Morrill JC, Cai J, Wu Q, Xu Y, Xue M, Arenkiel BR, Huang C, Tong Q. A neural basis for brain leptin action on reducing type 1 diabetic hyperglycemia. Nat Commun 2021; 12: 2662. PMID: 33976218, PMC8113586.

Xu, Y., Du, S., Marsh, J.A., Horie, K., Sato, C., Ballabio, A., Karch, C.M., Holtzman, D.M., and Zheng, H. TFEB regulates lysosomal exocytosis of tau and its loss of function exacerbates tau pathology and spreading. Mol Psych 2021; 26: 5925-5939. PMID: 32366951.

Chen W, Cai ZL, Chao ES, Chen H, Longley CM, Hao S, Chao HT, Kim JH, Messier JE, Zoghbi HY, Tang J, Swann JW, Xue M. Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy. Elife 2020; 9:e48705. PMID: 32073399, PMC7056272.

Kim ER, Xu Y, Cassidy RM, Lu Y, Yang Y, Tian J, Li DP, Van Drunen R, Ribas-Latre A, Cai ZL, Xue M, Arenkiel BR, Eckel-Mahan K, Xu Y, Tong Q. Paraventricular hypothalamus mediates diurnal rhythm of metabolism. Nat Commun 2020; 11: 3794. PMID: 32732906, PMC7393104.

Zhu C, Jiang Z, Xu Y, Cai ZL, Jiang Q, Xu Y, Xue M, Arenkiel BR, Wu Q, Shu G, Tong Q. Profound and redundant functions of arcuate neurons in obesity development. Nat Metab 2020; 2: 763-774. PMID: 32719538, PMC7687864.

Zhu C, Xu Y, Jiang Z, Tian JB, Cassidy RM, Cai Z-L, Shu G, Xu Y, Xue M, Arenkiel BR, Jiang Q, Tong Q. Disrupted hypothalamic CRH neuron responsiveness contributes to diet-induced obesity. EMBO Rep 2020; 21: e49210. PMID: 32462726, PMC7332802.

Deng S, Oka K. Adeno-Associated Virus as Gene Delivery Vehicle into the Retina. Methods Mol Biol 2020; 2092: 77-90. PMID: 31786783.