Wei Li Lab



Our research focuses on two broadly interrelated areas: ligandomics technology for drug target discovery and biological drug development for disease-targeting therapy. We created the first technology of ligandomics that led to multiple ongoing drug development projects. The goal of our ligandomics project is to develop an advanced ligand research tool that is capable of systematically mapping disease-selective ligands for in-depth understanding of disease mechanisms and facilitate drug target discovery. The goal of our drug development program is to independently validate disease-selective ligands as drug targets, generate neutralizing antibody to inhibit detrimental ligands, and develop therapeutic antibodies toward clinical translation.