Positions
- Associate Professor
-
Medicine-Gastroenterology
Baylor College of Medicine
Houston, TX US
- Member
-
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States
Education
- PhD from University Of Texas School Of Public Health
- 04/2004 - Houston, TX United States
- Molecular and genetic epidemiology of smoking-related pancreatic cancer
- MS from Chinese Academy Of Preventive Medicine
- 07/1997 - Beijing, China, People's Rep
- Interleukin 2 system in male smokers
- MD from Tongji Medical University
- 07/1994 - Wuhan, China, People's Rep
- Environmental Medicine
Professional Interests
- Epidemiology and outcomes of gastrointestinal cancers
- Molecular epidemiology
- Genetic epidemiology
- Dietary intake
- Obesity
- Biomarkers
- Insulin resistance
- Chronic inflammation
Professional Statement
Our research goals are to identify genetic and modifiable environmental risk factors for digestive cancers as well as to search for intermediate biomarkers of environment exposure and new targets for pharmaceutical or behavioral intervention. The current research is designed to understand the origin of chronic inflammation and disturbed immune homeostasis in population-based studies.Websites
Publications
New study reveals drinking coffee regularly can lead to this super coveted health benefit
Selected Publications
- Li D, Ahmed M, Li Y, Jiao L, Chou TH, Wolff RA, Lenzi R, Evans DB, Bondy ML, Pisters PW, Abbruzzese JL, Hassan MM "5,10-Methylenetetrahydrofolate reductase polymorphisms and the risk of pancreatic cancer.." Cancer Epidemiol. Biomarkers Prev.. 2005 Jun;14(6):1470-6. Pubmed PMID: 15941958
- Jiao L, Mitrou PN, Reedy J, Graubard BI, Hollenbeck AR, Schatzkin A, Stolzenberg-Solomon R "A combined healthy lifestyle score and risk of pancreatic cancer in a large cohort study.." Arch. Intern. Med.. 2009 Apr 27;169(8):764-70. Pubmed PMID: 19398688
- Bao Y, Stolzenberg-Solomon R, Jiao L, Silverman DT, Subar AF, Park Y, Leitzmann MF, Hollenbeck A, Schatzkin A, Michaud DS "Added sugar and sugar-sweetened foods and beverages and the risk of pancreatic cancer in the National Institutes of Health-AARP Diet and Health Study.." Am. J. Clin. Nutr.. 2008 Aug;88(2):431-40. Pubmed PMID: 18689380
- Jiao L, Taylor PR, Weinstein SJ, Graubard BI, Virtamo J, Albanes D, Stolzenberg-Solomon RZ "Advanced glycation end products, soluble receptor for advanced glycation end products, and risk of colorectal cancer.." Cancer Epidemiol. Biomarkers Prev.. 2011 Jul;20(7):1430-8. Pubmed PMID: 21527578
- Michaud DS, Vrieling A, Jiao L, Mendelsohn JB, Steplowski E, Lynch SM, Wactawski-Wende J, Arslan AA, Bas Bueno-de-Mesquita H, Fuchs CS, Gross M, Helzlsouer K, Jacobs EJ, Lacroix A, Petersen G, Zheng W, Allen N, Ammundadottir L, Bergmann MM, Boffetta P, Bu "Alcohol intake and pancreatic cancer: a pooled analysis from the pancreatic cancer cohort consortium (PanScan).." Cancer Causes Control. 2010 Aug;21(8):1213-25. Pubmed PMID: 20373013
- Jiao L, Silverman DT, Schairer C, Thiébaut AC, Hollenbeck AR, Leitzmann MF, Schatzkin A, Stolzenberg-Solomon RZ "Alcohol use and risk of pancreatic cancer: the NIH-AARP Diet and Health Study.." Am. J. Epidemiol.. 2009 May 1;169(9):1043-51. Pubmed PMID: 19299403
- Meinhold CL, Dodd KW, Jiao L, Flood A, Shikany JM, Genkinger JM, Hayes RB, Stolzenberg-Solomon RZ "Available carbohydrates, glycemic load, and pancreatic cancer: is there a link?." Am. J. Epidemiol.. 2010 Jun 1;171(11):1174-82. Pubmed PMID: 20452999
- Jiao L, Berrington de Gonzalez A, Hartge P, Pfeiffer RM, Park Y, Freedman DM, Gail MH, Alavanja MC, Albanes D, Beane Freeman LE, Chow WH, Huang WY, Hayes RB, Hoppin JA, Ji BT, Leitzmann MF, Linet MS, Meinhold CL, Schairer C, Schatzkin A, Virtamo J, Weinst "Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts.." Cancer Causes Control. 2010 Aug;21(8):1305-14. Pubmed PMID: 20383573
- Jacobs KB, Yeager M, Zhou W, Wacholder S, Wang Z, Rodriguez-Santiago B, Hutchinson A, Deng X, Liu C, Horner MJ, Cullen M, Epstein CG, Burdett L, Dean MC, Chatterjee N, Sampson J, Chung CC, Kovaks J, Gapstur SM, Stevens VL, Teras LT, Gaudet MM, Albanes D, "Detectable clonal mosaicism and its relationship to aging and cancer.." Nat. Genet.. 2012;44(6):651-8. Pubmed PMID: 22561519
- Thiébaut AC, Jiao L, Silverman DT, Cross AJ, Thompson FE, Subar AF, Hollenbeck AR, Schatzkin A, Stolzenberg-Solomon RZ "Dietary fatty acids and pancreatic cancer in the NIH-AARP diet and health study.." J. Natl. Cancer Inst.. 2009 Jul 15;101(14):1001-11. Pubmed PMID: 19561318
- Jiao L, Kramer JR, Rugge M, Parente P, Verstovsek G, Alsarraj A, El-Serag HB "Dietary intake of vegetables, folate, and antioxidants and the risk of Barrett's esophagus.." Cancer Causes Control. 2013 May;24(5):1005-14. Pubmed PMID: 23420329
- Li D, Li Y, Jiao L, Chang DZ, Beinart G, Wolff RA, Evans DB, Hassan MM, Abbruzzese JL "Effects of base excision repair gene polymorphisms on pancreatic cancer survival.." Int. J. Cancer. 2007 Apr 15;120(8):1748-54. Pubmed PMID: 17230526
- Jiao L, Weinstein SJ, Albanes D, Taylor PR, Graubard BI, Virtamo J, Stolzenberg-Solomon RZ "Evidence that serum levels of the soluble receptor for advanced glycation end products are inversely associated with pancreatic cancer risk: a prospective study.." Cancer Res.. 2011 May 15;71(10):3582-9. Pubmed PMID: 21540233
- Oaks BM, Dodd KW, Meinhold CL, Jiao L, Church TR, Stolzenberg-Solomon RZ "Folate intake, post-folic acid grain fortification, and pancreatic cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial.." Am. J. Clin. Nutr.. 2010 Feb;91(2):449-55. Pubmed PMID: 20007302
- Jiao L, Bondy ML, Hassan MM, Chang DZ, Abbruzzese JL, Evans DB, Smolensky MH, Li D "Glutathione S-transferase gene polymorphisms and risk and survival of pancreatic cancer.." Cancer. 2007 Mar 1;109(5):840-8. Pubmed PMID: 17265526
- Jiao L, Flood A, Subar AF, Hollenbeck AR, Schatzkin A, Stolzenberg-Solomon R "Glycemic index, carbohydrates, glycemic load, and the risk of pancreatic cancer in a prospective cohort study.." Cancer Epidemiol. Biomarkers Prev.. 2009 Apr;18(4):1144-51. Pubmed PMID: 19336549
- Jiao L, Doll MA, Hein DW, Bondy ML, Hassan MM, Hixson JE, Abbruzzese JL, Li D "Haplotype of N-acetyltransferase 1 and 2 and risk of pancreatic cancer.." Cancer Epidemiol. Biomarkers Prev.. 2007 Nov;16(11):2379-86. Pubmed PMID: 18006927
- Bao Y, Giovannucci EL, Kraft P, Qian ZR, Wu C, Ogino S, Gaziano JM, Stampfer MJ, Ma J, Buring JE, Sesso HD, Lee IM, Rifai N, Pollak MN, Jiao L, Lessin L, Cochrane BB, Manson JE, Fuchs CS, Wolpin BM "Inflammatory plasma markers and pancreatic cancer risk: a prospective study of five u.s. Cohorts.." Cancer Epidemiol. Biomarkers Prev.. 2013 May;22(5):855-61. Pubmed PMID: 23462920
- Suzuki H, Morris JS, Li Y, Doll MA, Hein DW, Liu J, Jiao L, Hassan MM, Day RS, Bondy ML, Abbruzzese JL, Li D "Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer.." Carcinogenesis. 2008 Jun;29(6):1184-91. Pubmed PMID: 18499698
- Jiao L, Zhu J, Hassan MM, Evans DB, Abbruzzese JL, Li D "K-ras mutation and p16 and preproenkephalin promoter hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking.." Pancreas. 2007 Jan;34(1):55-62. Pubmed PMID: 17198183
- Li D, Jiao L "Molecular epidemiology of pancreatic cancer.." Int J Gastrointest Cancer. 2003;33(1):41347. Pubmed PMID: 12909734
- Hassan MM, Abbruzzese JL, Bondy ML, Wolff RA, Vauthey JN, Pisters PW, Evans DB, Khan R, Lenzi R, Jiao L, Li D "Passive smoking and the use of noncigarette tobacco products in association with risk for pancreatic cancer: a case-control study.." Cancer. 2007 Jun 15;109(12):2547-56. Pubmed PMID: 17492688
- Li D, Duell EJ, Yu K, Risch HA, Olson SH, Kooperberg C, Wolpin BM, Jiao L, Dong X, Wheeler B, Arslan AA, Bueno-de-Mesquita HB, Fuchs CS, Gallinger S, Gross M, Hartge P, Hoover RN, Holly EA, Jacobs EJ, Klein AP, Lacroix A, Mandelson MT, Petersen G, Zheng W "Pathway analysis of genome-wide association study data highlights pancreatic development genes as susceptibility factors for pancreatic cancer.." Carcinogenesis. 2012 Jul;33(7):1384-90. Pubmed PMID: 22523087
- Jiao L, Chen L, Alsarraj A, Ramsey D, Duan Z, El-Serag HB "Plasma soluble receptor for advanced glycation end-products and risk of colorectal adenoma.." Int J Mol Epidemiol Genet. 2012;3(4):294-304. Pubmed PMID: 23205181
- Li D, Jiao L, Li Y, Doll MA, Hein DW, Bondy ML, Evans DB, Wolff RA, Lenzi R, Pisters PW, Abbruzzese JL, Hassan MM "Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer.." Carcinogenesis. 2006 Jan;27(1):103-11. Pubmed PMID: 15987714
- Jiao L, Chang P, Firozi PF, Lai D, Abbruzzese JL, Li D "Polymorphisms of phase II xenobiotic-metabolizing and DNA repair genes and in vitro N-ethyl-N-nitrosourea-induced O6-ethylguanine levels in human lymphocytes.." Mutat. Res.. 2007 Mar 5;627(2):146-57. Pubmed PMID: 17158087
- Hassan MM, Bondy ML, Wolff RA, Abbruzzese JL, Vauthey JN, Pisters PW, Evans DB, Khan R, Chou TH, Lenzi R, Jiao L, Li D "Risk factors for pancreatic cancer: case-control study.." Am. J. Gastroenterol.. 2007 Dec;102(12):2696-707. Pubmed PMID: 17764494
- Jiao L, Bondy ML, Hassan MM, Wolff RA, Evans DB, Abbruzzese JL, Li D "Selected polymorphisms of DNA repair genes and risk of pancreatic cancer.." Cancer Detect. Prev.. 2006;30(3):284-91. Pubmed PMID: 16844323
- Dong X, Jiao L, Li Y, Evans DB, Wang H, Hess KR, Abbruzzese JL, Li D "Significant associations of mismatch repair gene polymorphisms with clinical outcome of pancreatic cancer.." J. Clin. Oncol.. 2009 Apr 1;27(10):1592-9. Pubmed PMID: 19237629
- Li D, Liu H, Jiao L, Chang DZ, Beinart G, Wolff RA, Evans DB, Hassan MM, Abbruzzese JL "Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival.." Cancer Res.. 2006 Mar 15;66(6):3323-30. Pubmed PMID: 16540687
- Li D, Frazier M, Evans DB, Hess KR, Crane CH, Jiao L, Abbruzzese JL "Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer.." J. Clin. Oncol.. 2006 Apr 10;24(11):1720-8. Pubmed PMID: 16520463
- Okazaki T, Jiao L, Chang P, Evans DB, Abbruzzese JL, Li D "Single-nucleotide polymorphisms of DNA damage response genes are associated with overall survival in patients with pancreatic cancer.." Clin. Cancer Res.. 2008 Apr 1;14(7):2042-8. Pubmed PMID: 18381943
- Jiao L, Duan Z, Sangi-Haghpeykar H, Hale L, White DL, El-Serag HB "Sleep duration and incidence of colorectal cancer in postmenopausal women.." Br. J. Cancer. 2013 Jan 15;108(1):213-21. Pubmed PMID: 23287986
- Moy KA, Jiao L, Freedman ND, Weinstein SJ, Sinha R, Virtamo J, Albanes D, Stolzenberg-Solomon RZ "Soluble receptor for advanced glycation end products and risk of liver cancer.." Hepatology. 2013 Jun;57(6):2338-45. Pubmed PMID: 23325627
- Tasevska N, Jiao L, Cross AJ, Kipnis V, Subar AF, Hollenbeck A, Schatzkin A, Potischman N "Sugars in diet and risk of cancer in the NIH-AARP Diet and Health Study.." Int. J. Cancer. 2012 Jan 1;130(1):159-69. Pubmed PMID: 21328345
- Jiao L, Hassan MM, Bondy ML, Abbruzzese JL, Evans DB, Li D "The XPD Asp312Asn and Lys751Gln polymorphisms, corresponding haplotype, and pancreatic cancer risk.." Cancer Lett.. 2007 Jan 8;245(41276):61-8. Pubmed PMID: 16458430
- Jiao L, Hassan MM, Bondy ML, Wolff RA, Evans DB, Abbruzzese JL, Li D "XRCC2 and XRCC3 gene polymorphism and risk of pancreatic cancer.." Am. J. Gastroenterol.. 2008 Feb;103(2):360-7. Pubmed PMID: 17986315
Memberships
- American Association for Cancer Research
- Active member (01/2012)
Funding
- Advanced glycation end products and colorectal cancer risk in women - #1R03CA156626-01 (09/01/2011 - 08/31/2014) Grant funding from National Cancer Institute
- Pre-diagnostic circulating concentrations of CML-AGE and sRAGE and risk of colorectal cancer in a prospective case-cohort study.
- Advanced Glycation End-Products and Risk of Pancreatic Cancer - #1R01CA172880-01A1 (09/20/2013 - 07/31/2016) Grant funding from National Cancer Institute
- Toll-like receptors and risk of colorectal adenoma
- $60,000.00 (05/12/2012 - 05/31/2014) Gift funding from Gillson-Longenbaugh Foundation
- Toll-like receptors and colorectal cancer survival Gift funding from Golfers against cancer
- Toll-like receptors, gut microbiota, and risk of colorectal adenoma - #RP140767 (08/31/2014 - 08/30/2017) CPRIT (Cancer Prevention and Research Institute of Texas)
- 1. Targeted serum metabolites profiling in early detection of pancreatic cancer (01/01/2015 - 08/31/2015) Grant funding from NHLBI
- This study aims to identify metabolites specific to pancreatic cancer in a prospective study.
Skills
- molecular epidemiology study; genetics; statistics;
Languages
Chinese (Gan)
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