Baylor Remains Open

Baylor College of Medicine and its clinics will be open Monday, Nov. 28. We are closely monitoring the City of Houston's boil water advisory and will provide updates as needed.

Xiaolong Jiang Lab

Jiang Lab Publications



McKinney A, Hu M, Hoskins A, Mohammadyar A, Naeem N, Jing J, Patel SS, Sheth BR, Jiang X. Cellular and Circuit Organization of the Locus Coeruleus of Adult Mice. bioRxiv 2022.03.01.481656.

He L, Caudill M, Jing J, Wang W, Sun Y, Tang J, Jiang X, Zoghbi H. A weakened recurrent circuit in the hippocampus of Rett syndrome mice disrupts long-term memory representations. Neuron (2022), doi:https://doi.org/10.1016/j.neuron.2022.02.014

Lusk SJ, McKinney A, Hunt P, Fahey PG, Patel J, Chang A, Sun JJ, Martinez VK, Zhu PJ, Egbert JR, Allen G, Jiang X, Arenkiel BR, Tolias AS, Costa-Mattioli M, Ray RS. A CRISPR toolbox for generating intersectional genetic mouse models for functional, molecular, and anatomical circuit mapping. BMC Biol 20, 28 (2022).


Cheng J, Scala F, Blanco FA, Niu S, Firozi K, Keehan L, Mulherkar S, Froudarakis E, Li L, Duman JG, Jiang X, Tolias KF. The Rac-GEF Tiam1 Promotes Dendrite and Synapse Stabilization of Dentate Granule Cells and Restricts Hippocampal-Dependent Memory Functions. The Journal of neuroscience: the official journal of the Society for Neuroscience, 41(6), 1191–1206 (2021).


Jing J, Duncar C, Sonesra A, Chavez A, Park S, Soh H, Lee M, Tzingounis A, Cooper EC, Jiang X, Maheshwari A. Removal of KCNQ2 from Pawrvalbumin-expressing Interneurons Improves Anti-Seizure Efficacy of Retigabine. bioRxiv 2020.12.09.417295.

Scala F, Kobak D, Bernabucci M, Bernaerts Y, Cadwell CR, Castro JR, Hartmanis L, Jiang X, Laturnus S, Miranda E, Mulherkar S, Tan ZH, Yao Z, Zeng H, Sandberg R, Berens P, Tolias AS. Phenotypic variation of transcriptomic cell types in mouse motor cortex. Nature 598, 144–150 (2021).

Cadwell CR, Scala F, Fahey PG, Kobak D, Mulherkar S, Sinz FH, Papadopoulos S, Tan ZH, Johnsson P, Hartmanis L, Li S, Cotton RJ, Tolias KF, Sandberg R, Berens P, Jiang X, Tolias AS. Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex. Elife. 2020 Mar 5;9:e52951.

Shen S#, Jiang X#, Scala F, Reimer J, Fu J, Fahey P, Sinz. F, Tolias AS. Distinct organization of two cortico-cortical feedback pathways. bioRxiv 2020.02.27; #co-first authors.


17. Meng X, McGraw CM, Wang W, Jing J, Yeh S, Wang L, Lopez J, Brown AM, Lin T, Chen W, Xue M, Sillitoe RV, Jiang X, Zoghbi HJ. Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specificcerebellar synapses and motor functions. eLife. September 16, 2019; 8: e46773. doi: 10.7554/eLife.46773

Scala F, Kobak D, Shan S, Bernaerts Y, Laturnus S, Cadwell CR, Hartmanis H, Castro J, Tan ZH, Sandberg S, Berens P, Jiang X*, Tolias AT*. Neocortical layer 4 in adult mouse differs in major cell types and circuit organization between primary sensory areas. Nature Communication. September 13, 2019. Volume 10. *co-corresponding authors


F. Scala, D. Kobak, S. Shan, Y. Bernaerts, S. Laturnus, C.R. Cadwell, L. Hartmanis, E. Froudarakis, J. Castro, Z.H. Tan, S. Papadopoulos, S. Patel, R. Sandberg, P. Berens, X. Jiang,

A.S. Tolias. Neocortical layer 4 in adult mouse differs in major cell types and circuit organization between primary sensory areas. bioRxiv 507293; doi: https://doi.org/10.1101/507293.


Cadwell CR, Scala F, Li S, Livrizzi G, Shen S, Sandberg R, Jiang X* and Tolias, AS*. Multimodal profiling of single-cell morphology, electrophysiology and gene expression using Patch-seq. Nature Protocols. 2017 Dec;12(12):2531-2553. *co-corresponding authors.

CR Cadwell, R Sandberg, X Jiang, AS Tolias. Q&A: using Patch-seq to profile single cells. 2017. BMC biology 15 (1), 58,

A Chen, WW Hu, XL Jiang, M Potegal, H Li. Molecular mechanisms of group I metabotropic glutamate receptor mediated LTP and LTD in basolateral amygdala in vitro. 2017. Psychopharmacology 234 (4), 681-694.


Jiang X, Shen S, Cadwell CR, Berens P, Sinz F, Ecker AS, Patel S & Tolias AS (2015). Principles of Connectivity among Morphologically Defined Cell Types in Adult Neocortex. Science. Vol. 350 no. 6264 DOI: 10.1126

Cadwell CR, Palasantza A, Jiang X, Berens B, Deng Q, Yilmaz M, Reimer J, Bethge M, Tolias KF, Sandberg R and Tolias AS. High-throughput morphological, electrophysiological and transcriptomic profiling of single neurons. Nature Biotechnology. 2015 Dec 21.3.