Meeting Schedule (Meeting time is based on Central Standard Time)
Start Time: 8:30 a.m.
Introduction
- Time: 8:30 - 8:35 a.m. (5 min)
- Presenter: Yingbin Fu, Baylor College of Medicine
Session 1: Cornea
- Time: 8:35 - 9:25 a.m. (50 min)
- Moderator: Elizabeth Zuniga-Sanchez, Baylor College of Medicine
- The Importance of the Gut-Eye-Axis in Dry Eye – Cintia S. de Paiva, Baylor College of Medicine
- A one dose siRNA therapeutic to promote regenerative healing in the cornea – Audrey M. Bernstein, SUNY Upstate Medical University
Break
- Time: 9:25 - 9:30 a.m. (5 min)
Session 2: Age-related Macular Degeneration
- Time: 9:30 - 10:45 a.m. (75 min)
- Moderator: Wei Li, Baylor College of Medicine
- Using functional genomics to identify the mechanisms underlying age-related macular degeneration – Rinki Ratnapriya, Baylor College of Medicine
- Adenosine receptor 2a in subretinal fibrosis – Yuqing Huo, Baylor College of Medicine
- Mechanistic insight and treatment strategies for incomplete response to anti-VEGF therapies in AMD – Yingbin Fu, Baylor College of Medicine
Break
- Time: 10:45 - 10:50 a.m. (5 min)
Session 3: Glaucoma
- Time: 10:50 - 11:40 a.m. (50 min)
- Moderator: Rinki Ratnapriya, Baylor College of Medicine
- Uncover Microglial Activation and Neuroinflammation as Root Causes of Glaucoma – Dongfeng Chen, Massachusetts Eye and Ear
- Aberrant Wnt Signaling in the Pathogenesis of Glaucoma – Abbot Clark, University of North Texas Health Science Center
Lunch Break
- Time: 11:40 am - 12:10 p.m. (30 min)
Session 4: Keynote Presentation
- Time: 12:10 - 1:10 p.m. (60 min)
- Introduction: Samuel Wu, Baylor College of Medicine
- Speaker: Connie Cepko, Harvard Medical School & HHMI
- Topic: Gene-agnostic gene therapy to prolong vision
Break
- Time: 1:10 - 1:15 p.m. (5 min)
Session 5: Multiomics and Artificial Intelligence
- Time: 1:15 - 2:30 pm (75 min)
- Moderator: Rui Chen, University of California, Irvine
- Integrating human genetics with regulatory and single cell genomics uncovers causal mechanisms for glaucoma – Ayellet Segrè, Massachusetts Eye and Ear
- Type-specific features associated with retinal ganglion cell resilience and axon regeneration – Nicholas M. Tran, Baylor College of Medicine
- Deep-Learning and Statistical Methods for Single-cell Data Analyses – Xu Dong, University of Missouri-Columbia
Break
- Time: 2:30 - 2:35 p.m. (5 min)
Session 6: Immune Cells and Inflammation
- Time: 2:35 - 3:50 p.m. (75 min)
- Moderator: Cintia S. de Paiva, Baylor College of Medicine
- Immune cells: Unseen guardians of eye health and resilience – Daniel R. Saban, Duke University
- Crystallin γS: A molecule expressed by microglia for retinal protection – Eleftherios Paschalis Ilios, Massachusetts Eye and Ear
- Dry eye perturbs the balance between regulatory and inflammatory macrophages in the ocular surface – Stephen C. Pflugfelder, Baylor College of Medicine
Break
- Time: 3:50 - 3:55 p.m. (5 min)
Session 7: Retina
- Time: 3:55 - 5:35 pm (100 min)
- Moderator: Zheng Jiang and Samuel Wu, Baylor College of Medicine
- Context-dependent motion processing by the retina – Wei Wei, University of Chicago
- Circuit mechanisms in the retina shaping visual signaling at night – Jeffrey Diamond, NINDS
- Electrophysiological profiling and classification of retinal ganglion cell subtypes in the mouse retina – Zheng Jiang, Baylor College of Medicine
- Deciphering the developmental mechanisms of retinal circuit assembly – Elizabeth Zuniga-Sanchez, Baylor College of Medicine
Social Time
- Time: 5:35 - 6:35 p.m. (1 hour)