With the high rate of use of antimicrobial drugs throughout the world, the emergence and spread of drug-resistant pathogens is a major threat to long-term infection control. An increased understanding of pathogen evasion and persistence mechanisms as well as advances in immunology and host-microbe interactions have provided a foundation for new therapeutic targets and approaches to eradicate or control infections.
Our research in the Antibiotics, Antivirals, and Drug Resistance research area: seeks to answer fundamental questions about the evolution and mechanisms of drug resistance; develop new antimicrobial drugs; engineer gene and immune based-therapies; and develop microbial-based therapeutics.
Our group takes full advantage of the rich facilities in the College, each filled with state-of-the-art equipment and expertise, including the Human Genome Sequencing Center, the Alkek Center for Metagenomics and Microbiome Research, the Center for Drug Discovery, the Alkek Center for Molecular Discovery (including their Metabolomics Core), the Center for Cell and Gene Therapy, and the Cryo-Electron Microscopy Core.
Profiles of Faculty Working on Antibiotics, Antivirals and Drug Resistance
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