Email

amoye@bcm.edu

Positions

Postdoctoral Fellow

Biochemistry-Wensel Lab
Baylor College of Medicine
Houston, TX US

Addresses

BCM-Alkek Graduate School (Lab)

Room: BCMN-N430
Houston, TX 77030
United States

Education

BS from Marshall University

05/2013 - Huntington, West Virginia United States

PhD from West Virginia University

11/2018 - Morgantown, West Virginia United States

Honors & Awards

Deans Award of Excellence

Baylor College of Medicine

1st Place Members-In-Training Poster Award

ARVO International Conference

Postdoctoral Association President

Baylor College of Medicine (02/2021 - 07/2022)

Professional Development

ARL2BP, a ciliopathy protein linked to retinitis pigmentosa, controls axonemal growth

Conference (Presenter, 2017)

Sponsor: FASEB Biology of Cilia and Flagella

Invited Speaker

ARL2BP, a ciliopathy protein linked to retinitis pigmentosa, controls axonemal growth

Conference (Presenter, 2017)

Sponsor: ARVO

ARL2BP, a ciliopathy protein linked to retinitis pigmentosa, controls axonemal growth

Conference (Presenter, 2017)

Sponsor: Annual Van Liere Convocation Research Award, West Virginia University

1st Place

ARL2BP in health and disease

Conference (Presenter, 2016)

Sponsor: ARVO

Invited Speaker

Selected Publications

• Tanya L Dilan 1 2, Abigail R Moye 1 2, Ezequiel M Salido 1, Thamaraiselvi Saravanan 1, Saravanan Kolandaivelu 1 2, Andrew F X Goldberg 3, Visvanathan Ramamurthy 4 2 5 "ARL13B, a Joubert Syndrome-Associated Protein, Is Critical for Retinogenesis and Elaboration of Mouse Photoreceptor Outer Segments." J Neurosci .. 2019 Feb;20(39):1347-1364. Pubmed PMID: 30573647
• Abigail R Moye 1 2, Ratnesh Singh 2, Victoria A Kimler 3, Tanya L Dilan 1 2, Daniella Munezero 1 2, Thamaraiselvi Saravanan 1, Andrew F X Goldberg 3, Visvanathan Ramamurthy 1 2 4 "ARL2BP, a protein linked to retinitis pigmentosa, is needed for normal photoreceptor cilia doublets and outer segment structure." Mol Biol Cell. 2018 Jul 1;29(13):1590-1598. Pubmed PMID: 29718757
• Tanya L Dilan 1 2, Ratnesh K Singh 1 2, Thamaraiselvi Saravanan 1, Abigail Moye 1 2, Andrew F X Goldberg 3, Peter Stoilov 2, Visvanathan Ramamurthy 1 2 4 "Bardet-Biedl syndrome-8 (BBS8) protein is crucial for the development of outer segments in photoreceptor neurons." Hum Mol Genet. 2018 Jan 15;27(2):283-294. Pubmed PMID: 29126234
• Darius J Devlin 1 2, Smriti Agrawal Zaneveld 3 4, Kaori Nozawa 2 5, Xiao Han 3 4 6, Abigail R Moye 7, Qingnan Liang 3 4 7, Jacob Michael Harnish 4, Martin M Matzuk 2 4 5, Rui Chen 3 4 "Knockout of mouse receptor accessory protein 6 leads to sperm function and morphology defects." Biol Reprod. 2020 May 26;102(6):1234-1247. Pubmed PMID: 32101290

Funding

Cep290 function in photoreceptor structure and disease. - #EY031574

(08/10/2021 - 08/12/2024) Grant funding from NIH F32

Ciliopathies are a group of diseases caused by defects in the cilia and lead to syndromic diseases affecting multiple organs, including the eye. This proposal will investigate the role for a ciliopathy protein that is associated with multiple ciliopathies and blindness in humans. The completion of the proposed work is important for the identification of novel therapeutic approaches and will lay the foundation for the successful completion of clinical trials that will help patients around the world.

Skills

STORM microscopy

TEM

SIM Microscopy

Cloning

Mouse line generation/CRISPR

Molecular Biology