Anna Maria Mandalakas, M.D., MSEpi, Ph.D.
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Anna Maria Mandalakas, M.D., MSEpi, Ph.D.
Professor
Positions
- Professor
-
Pediatrics-Global Immigrant Health
Baylor College of Medicine
Houston, TX US
Addresses
- Texas Children's Hospital, Feigin Center (Clinic)
-
1102 Bates Street
Suite 630
Houston, TX 77030
United States
Phone: (832) 822-1331
Education
- PhD from Stellenbosch University
- 12/2015 - Stellenbosch, Western Cape South Africa
- Epidemiology
- Fellowship at Rainbow Babies & Children's Hospital/Case Western Reserve University
- 01/2000 - Cleveland, Ohio United States
- MS from Case Western Reserve University
- 01/2000 - Cleveland, Ohio United States
- Residency at Case Western Reserve University
- 05/1997 - Cleveland, Ohio United States
- Internship at Case Western Reserve University
- 08/1997 - Cleveland, Ohio United States
- MD from Hahnemann University
- 01/1994 - Philadelphia, Pennsylvania United States
- BA from Case Western Reserve University
- 01/1990 - Cleveland, Ohio United States
Professional Interests
- Pediatric Tuberculosis
- Pediatric HIV
- Global Health
Professional Statement
I have extensive experience conducting large-scale community based epidemiologic studies in the US and in resource-limited countries. Over the past 20 years, I have incrementally developed a clinical research platform from which to study the diagnosis, prevention, and pathophysiology of Mycobacterium tuberculosis infection in children. In 2012, I joined Baylor College of Medicine and Texas Children’s Hospital to establish and direct our Global TB Program. Collaborating with new colleagues and building upon the existing infrastructure of the Baylor Pediatric AIDS Initiative, we have created a translational research team and a unique research platform that aims to promote child survival and contribute knowledge to the field of childhood TB and HIV. Our translational research arena also affords an outstanding opportunity to train tomorrow’s Global Health leaders and develop capacity in the TB high-burden setting that we serve.Websites
Selected Publications
- Skinner D, Mandalakas AM "Pasting together the preventive therapy puzzle [Short communication].." Int. J. Tuberc. Lung Dis.. 2013 Feb;17(2):175-7. Pubmed PMID: 23211672
- Mandalakas AM, van Wyk S, Kirchner HL, Walzl G, Cotton M, Rabie H, Kriel B, Gie RP, Schaaf HS, Hesseling AC "Detecting tuberculosis infection in HIV-infected children: a study of diagnostic accuracy, confounding and interaction.." Pediatr. Infect. Dis. J.. 2013 Mar;32(3):e111-8. Pubmed PMID: 23190784
- Mandalakas AM, Hesseling AC, Gie RP, Schaaf HS, Marais BJ, Sinanovic E "Modelling the cost-effectiveness of strategies to prevent tuberculosis in child contacts in a high-burden setting.." Thorax. 2013 Mar;68(3):247-55. Pubmed PMID: 22717944
- Mandalakas AM, Kirchner HL, Lombard C, Walzl G, Grewal HM, Gie RP, Hesseling AC "Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection.." Int. J. Tuberc. Lung Dis.. 2012 Aug;16(8):1033-9. Pubmed PMID: 22692027
- Mandalakas AM, Detjen AK, Hesseling AC, Benedetti A, Menzies D "Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis.." Int. J. Tuberc. Lung Dis.. 2011 Aug;15(8):1018-32. Pubmed PMID: 21669030
- Van Wyk SS, Hamade H, Hesseling AC, Beyers N, Enarson DA, Mandalakas AM "Recording isoniazid preventive therapy delivery to children: operational challenges.." Int. J. Tuberc. Lung Dis.. 2010 May;14(5):650-3. Pubmed PMID: 20392361
- Mandalakas AM, Kirchner HL, Zhu X, Yeo KT, Starke JR "Interpretation of repeat tuberculin skin testing in international adoptees: conversions or boosting.." Pediatr. Infect. Dis. J.. 2008 Oct;27(10):913-9. Pubmed PMID: 18776820
- Mandalakas AM, Hesseling AC, Chegou NN, Kirchner HL, Zhu X, Marais BJ, Black GF, Beyers N, Walzl G "High level of discordant IGRA results in HIV-infected adults and children.." Int. J. Tuberc. Lung Dis.. 2008 Apr;12(4):417-23. Pubmed PMID: 18371268
- Mandalakas AM, Kirchner HL, Iverson S, Chesney M, Spencer MJ, Sidler A, Johnson D "Predictors of Mycobacterium tuberculosis infection in international adoptees.." Pediatrics. 2007 Sep;120(3):e610-6. Pubmed PMID: 17766501
- Mandalakas AM, Guay L, Musoke P, Carroll-Pankhurst C, Olness KN "Human immunodeficiency virus status and delayed-type hypersensitivity skin testing in Ugandan children.." Pediatrics. 1999 Feb;103(2):E21. Pubmed PMID: 9925867
- Mandalakas AM, Ngo K, Alonso Ustero P, Golin R, Anabwani F, Mzileni B,, Sikhondze W, Stevens R "BUTIMBA: Intensifying the Hunt for Child TB in Swaziland through Household Contact Tracing.." PLoS One. 2017 Jan 20;12(1):e0169769. Pubmed PMID: 28107473
- Szkwarko D, Hirsch-Moverman Y, Du Plessis L, Du Preez K, Carr C, Mandalakas AM "Child contact management in high tuberculosis burden countries: A mixed-methods systematic review." PLoS One. 2017 Aug 1;12(8):e0182185. Pubmed PMID: 28763500
- Detjen AK, DiNardo AR, Leyden J, Steingart KR, Menzies D, Schiller I, Dendukuri N, Mandalakas AM "Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis." Lancet Respir Med. 2015 Jun;3(6):451-61. Pubmed PMID: 25812968
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