Christopher Michael Johnson, MD, PhD
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Positions
- Assistant Professor
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Department of Medicine
Baylor College of Medicine
- Division Director of Gastroenterology
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Department of Medicine
Baylor Scott and White Health
Temple, Texas
Education
- BS from University of Illinois at Urbana-Champain
- 05/2003 - Urbana-Champaign, Illinois United States
- Cell and Structural Biology
- PhD from University of Illinois at Urbana-Champain
- 06/2007 - Urbana-Champaign, Illinois United States
- Microbiology and Immunology
- MD from University of Illinois College of Medicine
- 05/2011 - Chicago, Illinois United States
- Residency at Scott and White Healthcare, Texas A&M Health Science Center
- 06/2014 - Temple, Texas United States
- Internal Medicine
- Clinical Fellowship at Scott and White Healthcare, Texas A&M Health Science Center
- 06/2017 - Temple, Texas United States
- Gastroenterology
- Postdoctoral Training at University of Pittsburgh Medical Center
- 12/2016 - Pittsburgh
- Inflammatory Bowel Disease Research and Clinical Training
Certifications
- American Board of Internal Medicine
- Board Certified in Internal Medicine and Gastroenterology
Professional Interests
- Inflammatory Bowel Disease
- Clinical Trials and Outcomes Research in IBD
- Quality Improvement in Gastroenterology
Websites
Selected Publications
- Blaney H, Vu P, Mathew A, Snelling R, England J, Duong C, Hammonds K, Johnson CM "Anemia Severity Associated with Increased Healthcare Utilization and Costs in Inflammatory Bowel Disease." Dig. Dis. Sci.. 2020; Pubmed PMID: 32892260
- Tran P, Seth N, Najmi M, Fernandez M, Johnson, CM "Atypical Histiocytoid Sweet Syndrome in a Patient with Crohn’s Disease." ACG Case Rep.. 2023; Pubmed PMID: 37799480
- Johnson CM, Lyle EA, Omueti KO, Stepensky VA, Yegin O, Alpsoy E, Haman L, Schumann RR and RI Tapping "Cutting edge: A common polymorphism impairs cell surface expression and functional responses of Toll-like receptor 1 but protects against leprosy.." J. Immunol.. 2007; Pubmed PMID: 17548585
- Omueti KO, Beyer JM, Johnson CM, Lyle EA and RI Tapping "Domain exchange between human toll-like receptors 1 and 6 reveals region required for lipopeptide discrimination.." J. Biol. Chem.. 2005; Pubmed PMID: 16129684
- Johnson CM, Hartman, DJ, Ramos-Rivers C, Rao BB, Bhattacharya A, Regueiro M, Schwartz M, Swoger J, Baidoo L, Barrie A, Dunn M and Binion DG. "Epithelioid Granulomas Associate with Increased Severity and Progression of Crohn’s Disease, Based on 6-Year Follow-Up." Clin Gastroenterol Hepatol. 2018; Pubmed PMID: 29277619
- McDaniel K, Correa R, Zhou T, Johnson CM, Francis H, Glaser S, Venter J, Alpini G, Meng F "Functional role of microvesicles in gastrointestinal malignancies." Ann. Transl. Med. 2013; Pubmed PMID: 24432300
- Tapping RI, Omueti KO and Johnson CM "Genetic polymorphisms within the human Toll-like receptor 2 subfamily.." Biochem. Soc. Trans.. 2007; Pubmed PMID: 18031242
- 7. Johnson CM, Hargrove L, Graf A, Kennedy L, Hodges K, Harris R, Francis T, Ueno Y, Francis H. "Histamine restores biliary mass following carbon tetrachloride-induced damage in a cholestatic rat model.." Dig Liv Dis. 2015; Pubmed PMID: 25575430
- Johnson CM, Huynh V, Hargrove L, Kennedy L, Graf-Eaton A, Owens J, Trzeciakowski JP, Hodges K, DeMorrow S, Han Y, Wong L, Alpini G, Francis H "Inhibition of Mast Cell-Derived Histamine Decreases Human Cholangiocarcinoma Growth and Differentiation via c-Kit/Stem Cell Factor-Dependent Signaling." Am J Pathol.. 2016; Pubmed PMID: 26597881
- Jones H, Hargrove L, Kennedy L, Meng F, Graf-Eaton A, Owens J, Alpini G, Johnson CM, Bernuzzi F, Demieville J, DeMorrow S, Invernizzi P, Francis H. "Inhibition of mast cell-secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis Mdr2(-/-) mice.." Hepatology. 2016; Pubmed PMID: 27351144
- Johnson CM, Han Y, Hughart N, McCarra J, Alpini G and F Meng "Interleukin-6 and its receptor, key players in hepatobiliary inflammation and cancer.." Transl Gastrointest Cancer. 2012; Pubmed PMID: 22724089
- Johnson CM, Linzay, CL, Dassopoulos TD "Maneuvering Clinical Pathways for Ulcerative Colitis." Curr Gastroenterol Rep. 2019; Pubmed PMID: 31486929
- Bejcek A, Ancha A, Amundsen, T, Rodich S, Smith S, Johnson CM "Marginal Artery of Drummond Masquerading as a Fistulous Tract Resulting in Recurrent Lower Gastrointestinal Bleeding.." ACG Case Rep.. 2023; Pubmed PMID: 37928236
- Shah, R, Kelley, J, Amundsen, T, Coggins, K, Edwards, A, Johnson, CM. "Medical and social determinants of health as predictors of adverse outcomes in patients with inflammatory bowel disease." Proc (Bayl Univ Med Cent). 2022; Pubmed PMID: 36876274
- Johnson CM and RI Tapping "Microbial Products Stimulate Human Toll-like Receptor 2 Expression Through Histone Modification Surrounding a Proximal NF-κB Binding Site.." J. Biol. Chem.. 2007; Pubmed PMID: 17728249
- Sandhu G, Smith S, Stephenson K, Jaeger V, John, R, Shaver C, Johnson, CM "Prevalence of cannabinoid hyperemesis syndrome and its financial burden on the health care industry." Proc (Bayl Univ Med Cent). 2021; Pubmed PMID: 34732980
- Underhill N, Kennedy L, Johnson CM "Sleep Disorders in Inflammatory Bowel Disease.." J. Sleep Med Disorders. 2023;
- Johnson CM, Dassopoulos TD "Update on the use of thiopurines and methotrexate in inflammatory bowel disease." Curr Gastroenterol Rep. 2018; Pubmed PMID: 30267281
Memberships
- American College of Gastroenterology
- American Gastroenterology Association
- Crohn's and Colitis Foundation
- Texas Medical Association
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