Dimitrios Laurin Wagner, M.D., Ph.D.
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Dimitrios Laurin Wagner, M.D., Ph.D.
Assistant Professor
Positions
- Assistant Professor
-
Center for Gene Therapy
Baylor College of Medicine
Addresses
- BCM/CAGT - Feigin Center (Office)
-
1102 BATES AVE
Houston, TX 77030
United States
Education
- MD-PhD from Charité - Universitätsmedizin Berlin
- 06/2021 - Berlin, Germany
- MD from Charité - Universitätsmedizin Berlin
- 12/2019 - Berlin, Germany
- Research Fellowship at Baylor College of Medicine
- 12/2016 - Houston
Selected Publications
- "Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells." Blood. 2024; Pubmed PMID: 38493479
- "Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells." Genome Biol. 2023; Pubmed PMID: 37095570
- "Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells." Mol Ther Methods Clin Dev. 2022; Pubmed PMID: 35573047
- "High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population." Nat Med. 2019; Pubmed PMID: 30374197
- "Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours." Nat Rev Clin Oncol. 2023; Pubmed PMID: 36418477
- "Immunogenicity of CAR T cells in cancer therapy." Nat Rev Clin Oncol. 2021; Pubmed PMID: 33633361
Memberships
- American Society for Gene and Cell Therapy
- Member (03/2027)
- American Society for Gene and Cell Therapy
- Committee Member 'Genome Editing' (06/2019 - 05/2025)
- American Society for Gene and Cell Therapy
- Committee Member 'Immune Responses to Gene Therapy' (06/2019 - 05/2025)
- European Society for Gene and Cell Therapy
- Academic Member (07/2017)
- German Society for Gene Therapy (DG-GT e.V.)
- Academic Member (01/2020)
- Federation of Clinical Immunology Societies
- Scientific Program Committee (08/2023 - 07/2026)
- Dan L Duncan Comprehensive Cancer Center
- Research Member (04/2024)
- American Society for Gene and Cell Therapy
- Editorial Board MTMCD (01/2024)
Languages
German
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