Positions

Assistant Professor

Molecular and Human Genetics
Baylor College of Medicine

Assistant Clinical Director

Baylor Genetics

Education

Fellowship at Baylor College of Medicine

Houston

Postdoctoral Training at Baylor College of Medicine

04/2013 - Houston

PhD from National Taiwan University

01/2011 - Taipei, Taiwan

Professional Statement

As a clinical laboratory director specializing in whole genome and whole exome sequencing (WGS/WES), my primary focus is the interpretation of complex genomic data in the clinical setting. I contribute to accurate and timely molecular diagnoses, with a particular interest in discovering novel gene-disease associations. My goal is to advance our understanding of rare and undiagnosed conditions, ultimately improving patient care and expanding the field of medical genetics.

Websites

Selected Publications

• Kao EC, Vossaert L, Mizerik EA, Bacino CA, Dai H, Scott DA "MED12 loss-of-function variants as a cause of congenital diaphragmatic hernia in females With Hardikar syndrome and nonspecific intellectual disability." Am J Med Genet A. 2025;197:e63868.
• Mohan P, Lemoine J, Trotter C, Rakova I, Billings P, Peacock S, Kao CY, Wang Y, Xia F, Eng CM, Benn P "Clinical Experience with non-invasive prenatal screening for single-gene disorders." Ultrasound Obstet Gynecol. 2022;59:33-39.
• Kao CY*, Xu M*, Wang L*, Lin SC, Lee HJ, Duranie L, Bellen HJ, Goldstein DS, Tsai SY, Tsai MJ "Elevated COUP-TFII expression in dopaminergic neurons accelerates the progression of Parkinson’s disease through mitochondrial dysfunction." PLoS Genet. 2020;16:e1008868.
• Wu SP, Kao CY, Wang L, Creighton CJ, Yang J, Donti TR, Harmancey R, Vasquez HG, Graham BH, Bellen HJ, Taegtmeyer H, Chang CP, Tsai MJ, Tsai SY "Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure." Nat Commun. 2015;6:8245.