Imen Chakchouk, Ph.D.
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Imen Chakchouk, Ph.D.
Instructor
Positions
- Instructor
-
Baylor College of Medicine
Houston, Texas United States
- Postdoctoral Associate
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Obstetrics & Gynecology / Van den Veyver' s Lab
Baylor College of Medicine
Houston, TX US
Addresses
- The Jan & Dan Duncan Neurological Research Institute at Texas Children’s Hospital (Lab)
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Suite N1025
Houston, TX 77030
United States
Projects
- TECHNOLOGY DEVELOPMENT FOR NONINVASIVE PRENATAL GENETIC DIAGNOSIS USING MATERNAL PERIPHERAL BLOOD
- The goal of this study is to develop and validate a new risk-free prenatal diagnosis tool using only the maternal peripheral blood for the detection of clinically relevant genomic imbalance in the developing fetus.
- CHARACTERIZATION OF THE ROLE OF MATERNAL EFFECT GENE NLRP2 IN REPRODUCTION
- Maternal mutations in human NLRP7 cause recurrent hydatidiform molar (RHM) pregnancies with imprinting defects. Maternal mutations in a highly homologous gene NLRP2, cause multi-locus imprinting disorder (MLID) in offspring. Both disorders are associated with abnormal DNA methylation of maternally imprinted genes. Using Nlrp2 knock-out mouse and human embryonic stem cells models to study the mechanisms that cause the observed offsprings and placental abnormalities.
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