Jeffrey Stephen Heinle, M.D.
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Positions
- Professor and Chief
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Division of Congenital Heart Surgery
Baylor College of Medicine
- Surgical Director, Lung Transplant
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Texas Children's Hospital
- Professor of Pediatrics
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Baylor College of Medicine
- Brad and Melissa Juneau Endowed Chair in Congenital Heart Surgery
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Texas Children's Hospital
- Co-Director, Heart Center
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Texas Children's Hospital
Addresses
- Texas Children's West Tower (Clinic)
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6621 Fannin Street
20th Floor
Houston, TX 77030
United States
Phone: (832) 826-2030
Congenital Heart Surgery
Education
- Residency from Duke University School of Medicine
- 01/1995 - Durham, NC United States
- B.S. from Duke University
- 01/1982 - Durham, NC United States
- Advanced Training from Boston Children's Hospital
- 01/1986 - Boston, MA United States
- M.D. from University of Pittsburgh
- 01/1987 - Pittsburgh, PA United States
- Advanced Training from University of Pennsylvania
- 01/1988 - Philadelphia, PA United States
- Intern and Junior Assistant Resi from University of Pennsylvania
- 01/1989 - Philadelphia, PA United States
- Fellow, Cardiovascular Surgery from Brigham And Women's Hospital
- 01/1996 - Boston, Massachusetts United States
- Fellow, Pediatric Cardiovascular from Boston Children's Hospital
- 01/1996 - Boston, MA United States
Certifications
- Thoracic Surgery
- American Board of Thoracic Surgery
- General Surgery
- American Board of Surgery
- National Board of Medical Examiners
Honors & Awards
- Star Award for Excellence in Patient Care
- Baylor College of Medicine
Professional Interests
- Congenital Heart Surgery
- Fontans procedure
- Glenn shunt
- Heart and lung transplants
- Norwood operation
- Patent ductus arteriosus ligation
- Rastelli procedure
- Repair of Ebstein's anomaly
- Repair of anomalous coronary artery
- Ross procedure
- Tetralogy of Fallot repair
- Aortic arch advancement
- Aortic valve stenosis repair
- Arterial switch
- Atrial septal defect and ventricular septal defect closures
- Atrioventricular canal defect repair
- Blalock-Taussig shunt
- Coarctation of the aorta repair
- Double-switch procedures
Professional Statement
Dr. Jeffrey S. Heinle’s research interests include, but are not limited to, cerebral and myocardial protection during cardiac surgery, early extubation following congenital heart surgery, minimally invasive procedures in congenital heart surgery, advances in congenital heart surgery, and improving the outcomes following congenital heart surgery. Dr. Heinle has authored or co-authored 12 articles for scholarly and professional publications, such as the Journal of Thoracic and Cardiovascular Surgery, Surgical Forum, Transplantation, Annals of Thoracic Surgery, and the Journal of Surgical Research. He has also authored or co-authored seven book chapters, and has presented his research to professional audiences. His writing and speaking topics have included early extubation of neonates and young infants after cardiac surgery; cerebral metabolic effects of hypothermic circulatory arrest; myocardial protection during congenital heart surgery; congenital anomalies of the chest wall; surgery for congenital heart disease; and heart valve recovery, preservation, and transplantation.Websites
Congenital Heart Surgery at Texas Children's
VIICTR Research Database
Two Years Later: Life After Open-Heart Surgery
Selected Publications
- Morales DL, Adachi I, Heinle JS, Fraser CD "A new era: Use of an intracorporeal systemic ventricular assist device to support a patient with a failing Fontan circulation.." J. Thorac. Cardiovasc. Surg.. 2011 Sep;142(3):e138-40. Pubmed PMID: 21762934
- Carlo WF, Carberry KE, Heinle JS, Morales DL, McKenzie ED, Fraser CD, Nelson DP "Interstage attrition between bidirectional Glenn and Fontan palliation in children with hypoplastic left heart syndrome.." J. Thorac. Cardiovasc. Surg.. 2011 Sep;142(3):511-6. Pubmed PMID: 21704339
- McKenzie ED, Klysik M, Morales DL, Heinle JS, Fraser CD, Kovalchin J "Ascending sliding arch aortoplasty: a novel technique for repair of arch hypoplasia.." Ann. Thorac. Surg.. 2011 Mar;91(3):805-10. Pubmed PMID: 21353003
- Scully BB, Zafar F, Schecter MG, Rossano JW, Mallory GB, Heinle JS, Morales DL "Lung retransplantation in children: appropriate when selectively applied.." Ann. Thorac. Surg.. 2011 Feb;91(2):574-9. Pubmed PMID: 21256317
- Zafar F, Heinle JS, Schecter MG, Rossano JW, Mallory GB, Elidemir O, Morales DL "Two decades of pediatric lung transplant in the United States: Have we improved?." J. Thorac. Cardiovasc. Surg.. 2011 Mar;141(3):828-832.e1. Pubmed PMID: 21255797
- Morales DL, Zafar F, Rossano JW, Salazar JD, Jefferies JL, Graves DE, Heinle JS, Fraser CD "Use of ventricular assist devices in children across the United States: analysis of 7.5 million pediatric hospitalizations.." Ann. Thorac. Surg.. 2010 Oct;90(4):1313-9. Pubmed PMID: 20868835
- Rosen JB, Schecter MG, Heinle JS, McKenzie ED, Morales DL, Dishop MK, Danziger-Isakov L, Mallory GB, Elidemir O "Clostridium difficile colitis in children following lung transplantation.." Pediatr Transplant. 2010 Aug 1;14(5):651-6. Pubmed PMID: 20561346
- DiBardino DJ, Heinle JS, Kung GC, Leonard GT, McKenzie ED, Su JT, Fraser CD "Anatomic reconstruction for recurrent aortic obstruction in infants and children.." Ann. Thorac. Surg.. 2004 Sep;78(3):926-32; discuss. Pubmed PMID: 15337022
- Dibardino DJ, Heinle JS, Andropoulos DA, Kerr CD, Morales DL, Fraser CD "Aortic atresia and type B interrupted aortic arch: diagnosis by physiologic cerebral monitoring.." Ann. Thorac. Surg.. 2005 May;79(5):1758-60. Pubmed PMID: 15854973
- Andropoulos DB, Hunter JV, Nelson DP, Stayer SA, Stark AR, McKenzie ED, Heinle JS, Graves DE, Fraser CD "Brain immaturity is associated with brain injury before and after neonatal cardiac surgery with high-flow bypass and cerebral oxygenation monitoring.." J. Thorac. Cardiovasc. Surg.. 2010 Mar;139(3):543-56. Pubmed PMID: 19909994
- Mault JR, Whitaker EG, Heinle JS, Lodge AJ, Greeley WJ, Ungerleider RM "Cerebral metabolic effects of sequential periods of hypothermic circulatory arrest.." Ann. Thorac. Surg.. 1994 Jan;57(1):96-100; discuss. Pubmed PMID: 8279927
- Mault JR, Ohtake S, Klingensmith ME, Heinle JS, Greeley WJ, Ungerleider RM "Cerebral metabolism and circulatory arrest: effects of duration and strategies for protection.." Ann. Thorac. Surg.. 1993 Jan;55(1):57-63; discussi. Pubmed PMID: 8417712
- Andropoulos DB, Easley RB, Brady K, McKenzie ED, Heinle JS, Dickerson HA, Shekerdemian L, Meador M, Eisenman C, Hunter JV, Turcich M, Voigt RG, Fraser CD "Changing Expectations for Neurological Outcomes After the Neonatal Arterial Switch Operation.." 2012 Jun 28; Pubmed PMID: 22748448
- Scully BB, Morales DL, Zafar F, McKenzie ED, Fraser CD, Heinle JS "Current expectations for surgical repair of isolated ventricular septal defects.." Ann. Thorac. Surg.. 2010 Feb;89(2):544-9; discussi. Pubmed PMID: 20103339
- Zafar F, Khan MS, Heinle JS, Adachi I, McKenzie ED, Schecter MG, Mallory GB, Morales DL "Does donor arterial partial pressure of oxygen affect outcomes after lung transplantation? A review of more than 12,000 lung transplants.." J. Thorac. Cardiovasc. Surg.. 2012 Apr;143(4):919-25. Pubmed PMID: 22341426
- Heinle JS, Diaz LK, Fox LS "Early extubation after cardiac operations in neonates and young infants.." J. Thorac. Cardiovasc. Surg.. 1997 Sep;114(3):413-8. Pubmed PMID: 9305193
- Andropoulos DB, Mizrahi EM, Hrachovy RA, Stayer SA, Stark AR, Heinle JS, McKenzie ED, Dickerson HA, Meador MR, Fraser CD "Electroencephalographic seizures after neonatal cardiac surgery with high-flow cardiopulmonary bypass.." Anesth. Analg.. 2010 Jun;110(6):1680-5. Pubmed PMID: 20435942
- Morales DL, Braud BE, Gunter KS, Carberry KE, Arrington KA, Heinle JS, McKenzie ED, Fraser CD "Encouraging results for the Contegra conduit in the problematic right ventricle-to-pulmonary artery connection.." J. Thorac. Cardiovasc. Surg.. 2006 Sep;132(3):665-71. Pubmed PMID: 16935124
- Peterseim DS, Meyers CH, Craig DM, Heinle JS, Jayawant AM, Devaney JJ, Klitzman BM, Van Trigt P "Enhanced cardiac preservation with oxygenated University of Wisconsin solution.." J. Surg. Res.. 1993 Dec;55(6):588-94. Pubmed PMID: 8246491
- Andropoulos DB, Brady K, Easley RB, Dickerson HA, Voigt RG, Shekerdemian LS, Meador MR, Eisenman CA, Hunter JV, Turcich M, Rivera C, McKenzie ED, Heinle JS, Fraser CD "Erythropoietin neuroprotection in neonatal cardiac surgery: A phase I/II safety and efficacy trial.." J. Thorac. Cardiovasc. Surg.. 2013 Jul;146(1):124-31. Pubmed PMID: 23102686
- Kirk AD, Heinle JS, Mault JR, Sanfilippo F "Ex vivo characterization of human anti-porcine hyperacute cardiac rejection.." Transplantation. 1993 Oct;56(4):785-93. Pubmed PMID: 8212196
- Salazar JD, Zafar F, Siddiqui K, Coleman RD, Morales DL, Heinle JS, Rossano JW, Mossad EB, Fraser CD "Fenestration during Fontan palliation: now the exception instead of the rule.." J. Thorac. Cardiovasc. Surg.. 2010 Jul;140(1):129-36. Pubmed PMID: 20620378
- Suominen PK, Dickerson HA, Moffett BS, Ranta SO, Mott AR, Price JF, Heinle JS, McKenzie ED, Fraser CD, Chang AC "Hemodynamic effects of rescue protocol hydrocortisone in neonates with low cardiac output syndrome after cardiac surgery.." Pediatr Crit Care Med. 2005 Nov;6(6):655-9. Pubmed PMID: 16276331
- Morales DL, Braud BE, Booth JH, Graves DE, Heinle JS, McKenzie ED, Fraser CD "Heterotaxy patients with total anomalous pulmonary venous return: improving surgical results.." Ann. Thorac. Surg.. 2006 Nov;82(5):1621-7; discuss. Pubmed PMID: 17062215
- Law SP, Kim JJ, Decker JA, Price JF, Cabrera AG, Graves DE, Morales DL, Heinle JS, Denfield SW, Dreyer WJ, Rossano JW "Hospital charges for pediatric heart transplant hospitalizations in the United States from 1997 to 2006.." J. Heart Lung Transplant.. 2012 May;31(5):485-91. Pubmed PMID: 22306440
- Robertson J, Elidemir O, Saz EU, Gulen F, Schecter M, McKenzie E, Heinle J, Smith E, Mallory G "Hypogammaglobulinemia: Incidence, risk factors, and outcomes following pediatric lung transplantation.." Pediatr Transplant. 2009 Sep;13(6):754-9. Pubmed PMID: 19067916
- Morales DL, Scully PT, Braud BE, Booth JH, Graves DE, Heinle JS, McKenzie ED, Fraser CD "Interrupted aortic arch repair: aortic arch advancement without a patch minimizes arch reinterventions.." Ann. Thorac. Surg.. 2006 Nov;82(5):1577-83; discus. Pubmed PMID: 17062208
- Khan MS, Heinle JS, Samayoa AX, Adachi I, Schecter MG, Mallory GB, Morales DL "Is lung transplantation survival better in infants? Analysis of over 80 infants.." J. Heart Lung Transplant.. 2013 Jan;32(1):44-9. Pubmed PMID: 23164533
- Khan MS, Mery CM, Zafar F, Adachi I, Heinle JS, Cabrera AG, Fraser CD, Morales DL "Is mechanically bridging patients with a failing cardiac graft to retransplantation an effective therapy? Analysis of the United Network of Organ Sharing database.." J. Heart Lung Transplant.. 2012 Nov;31(11):1192-8. Pubmed PMID: 22906499
- Zhu D, Bryant R, Heinle J, Nihill MR "Isolated cleft of the mitral valve: clinical spectrum and course.." Tex Heart Inst J. 2009;36(6):553-6. Pubmed PMID: 20069080
- Dibardino DJ, Fraser CD, Dickerson HA, Heinle JS, McKenzie ED, Kung G "Left ventricular inflow obstruction associated with persistent left superior vena cava and dilated coronary sinus.." J. Thorac. Cardiovasc. Surg.. 2004 Apr;127(4):959-62. Pubmed PMID: 15052190
- Morales DL, Dibardino DJ, McKenzie ED, Heinle JS, Chang AC, Loebe M, Noon GP, DeBakey ME, Fraser CD "Lessons learned from the first application of the DeBakey VAD Child: an intracorporeal ventricular assist device for children.." J. Heart Lung Transplant.. 2005 Mar;24(3):331-7. Pubmed PMID: 15737761
- Rama JA, Fan LL, Faro A, Elidemir O, Morales DL, Heinle JS, Smith EO, Hazen ML, Moonnumakal SP, Mallory GB, Schecter MG "Lung transplantation for childhood diffuse lung disease.." Pediatr. Pulmonol.. 2012 Sep 4; Pubmed PMID: 22949409
- Kim JJ, Denfield SW, McKenzie ED, Fraser CD, Heinle JS, Goldstein S, Towbin JA, Dreyer WJ "Mechanical circulatory support as a bridge to combined dual organ transplantation in children.." J. Heart Lung Transplant.. 2006 Dec;25(12):1480-2. Pubmed PMID: 17178345
- Zaidi S, Elidemir O, Heinle JS, McKenzie ED, Schecter MG, Kaplan SL, Dishop MK, Kearney DL, Mallory GB "Mycobacterium abscessus in cystic fibrosis lung transplant recipients: report of 2 cases and risk for recurrence.." Transpl Infect Dis. 2009 Jun;11(3):243-8. Pubmed PMID: 19298240
- Heinle JS, Lodge AJ, Mault JR, Whitaker EG, Ungerleider RM "Myocardial function is normal after rapid cooling of the in vivo neonatal heart.." Ann. Thorac. Surg.. 1994 Feb;57(2):326-31; discuss. Pubmed PMID: 8311592
- Fujiwara T, Heinle J, Britton L, Mayer JE "Myocardial preservation in neonatal lambs. Comparison of hypothermia with crystalloid and blood cardioplegia.." J. Thorac. Cardiovasc. Surg.. 1991 Apr;101(4):703-12. Pubmed PMID: 2008109
- Fujiwara T, Kurtts T, Anderson W, Heinle J, Mayer JE "Myocardial protection in cyanotic neonatal lambs.." J. Thorac. Cardiovasc. Surg.. 1988 Nov;96(5):700-10. Pubmed PMID: 3184964
- Andropoulos DB, Easley RB, Brady K, McKenzie ED, Heinle JS, Dickerson HA, Shekerdemian LS, Meador M, Eisenman C, Hunter JV, Turcich M, Voigt RG, Fraser CD "Neurodevelopmental Outcomes After Regional Cerebral Perfusion With Neuromonitoring for Neonatal Aortic Arch Reconstruction.." 2012 Jul 3; Pubmed PMID: 22766302
- Heinle JS, Carberry KE, McKenzie ED, Liou A, Katigbak PA, Fraser CD "Outcomes after the palliative arterial switch operation in neonates with single-ventricle anatomy.." Ann. Thorac. Surg.. 2013 Jan;95(1):212-9. Pubmed PMID: 23200238
- Morales DL, Dreyer WJ, Denfield SW, Heinle JS, McKenzie ED, Graves DE, Price JF, Towbin JA, Frazier OH, Cooley DA, Fraser CD "Over two decades of pediatric heart transplantation: how has survival changed?." J. Thorac. Cardiovasc. Surg.. 2007 Mar;133(3):632-9. Pubmed PMID: 17320556
- Schecter MG, Elidemir O, Heinle JS, McKenzie ED, Mallory GB "Pediatric lung transplantation: a therapy in its adolescence.." Semin Thorac Cardiovasc Surg Pediatr Card Sur. 2008;74-9. Pubmed PMID: 18396229
- Khan MS, Heinle JS "Pediatric thoracic multiorgan transplantation.." Tex Heart Inst J. 2012;39(6):850-1. Pubmed PMID: 23304033
- Morales DL, Braud BE, DiBardino DJ, Carberry KE, McKenzie ED, Heinle JS, Fraser CD "Perimount bovine pericardial valve to restore pulmonary valve competence late after right ventricular outflow tract repair.." 2007 Mar;2(2):115-20. Pubmed PMID: 18377487
- Shamszad P, Cabrera AG, Kim JJ, Moffett BS, Graves DE, Heinle JS, Rossano JW "Perioperative atrial tachycardia is associated with increased mortality in infants undergoing cardiac surgery.." J. Thorac. Cardiovasc. Surg.. 2012 Aug;144(2):396-401. Pubmed PMID: 22306216
- Elidemir O, Kancherla BS, Schecter MG, McKenzie ED, Morales DL, Heinle JS, Mallory GB "Post-transplant lymphoproliferative disease in pediatric lung transplant recipients: recent advances in monitoring.." Pediatr Transplant. 2009 Aug;13(5):606-10. Pubmed PMID: 19017289
- Rossano JW, Kim JJ, Decker JA, Price JF, Zafar F, Graves DE, Morales DL, Heinle JS, Bozkurt B, Towbin JA, Denfield SW, Dreyer WJ, Jefferies JL "Prevalence, morbidity, and mortality of heart failure-related hospitalizations in children in the United States: a population-based study.." J. Card. Fail.. 2012 Jun;18(6):459-70. Pubmed PMID: 22633303
- Kealey GP, Chang P, Heinle J, Rosenquist MD, Lewis RW "Prospective comparison of two management strategies of central venous catheters in burn patients.." J Trauma. 1995 Mar;38(3):344-9. Pubmed PMID: 7897712
- Morales DL, Zafar F, Arrington KA, Gonzalez SM, McKenzie ED, Heinle JS, Fraser CD "Repeat sternotomy in congenital heart surgery: no longer a risk factor.." Ann. Thorac. Surg.. 2008 Sep;86(3):897-902; discus. Pubmed PMID: 18721579
- Morales DL, Zafar F, Heinle JS, Ocampo EC, Kim JJ, Relyea K, Fraser CD "Right Ventricular Infundibulum Sparing (RVIS) Tetralogy of Fallot Repair: A Review of Over 300 Patients.." Ann. Surg.. 2009 Oct;250(4):611-7. Pubmed PMID: 19734777
- Morales DL, Dibardino DJ, Braud BE, Fenrich AL, Heinle JS, Vaughn WK, McKenzie ED, Fraser CD "Salvaging the failing Fontan: lateral tunnel versus extracardiac conduit.." Ann. Thorac. Surg.. 2005 Oct;80(4):1445-51; discus. Pubmed PMID: 16181885
- Morales DL, Carberry KE, Balentine C, Heinle JS, McKenzie ED, Fraser CD "Selective application of the pediatric Ross procedure minimizes autograft failure.." ;3(6):404-10. Pubmed PMID: 19037980
- Falkensammer CB, Heinle JS, Chang AC "Serial plasma BNP levels in assessing inadequate left ventricular decompression on ECMO.." Pediatr Cardiol. 2008 Jul;29(4):808-11. Pubmed PMID: 18392789
- Law MA, Dreyer Z, Heinle JS, Dickerson HA "Staged single-ventricle palliation in an infant with hemoglobin SC disease.." Tex Heart Inst J. 2007;34(4):439-41. Pubmed PMID: 18172525
- McKenzie ED, Khan MS, Samayoa AX, Vener DS, Ishak YM, Santos AB, Heinle JS, Fraser CD "The Blalock-Taussig shunt revisited: a contemporary experience.." J. Am. Coll. Surg.. 2013 Apr;216(4):699-704. Pubmed PMID: 23415555
- Pruitt SK, Kirk AD, Bollinger RR, Marsh HC, Collins BH, Levin JL, Mault JR, Heinle JS, Ibrahim S, Rudolph AR "The effect of soluble complement receptor type 1 on hyperacute rejection of porcine xenografts.." Transplantation. 1994 Feb;57(3):363-70. Pubmed PMID: 8108871
- Breinholt JP, Fraser CD, Dreyer WJ, Chang AC, O'Brian Smith E, Heinle JS, Dean McKenzie E, Clunie SK, Towbin JA, Denfield SW "The efficacy of mitral valve surgery in children with dilated cardiomyopathy and severe mitral regurgitation.." Pediatr Cardiol. 2008 Jan;29(1):13-8. Pubmed PMID: 17849076
- DiBardino DJ, Heinle JS, Fraser CD "The hemi-Mustard, bi-directional Glenn, and Rastelli operations used for correction of congenitally corrected transposition, achieving a ventricle and a half " repair."." Cardiol Young. 2004 Jun;14(3):330-2. Pubmed PMID: 15680031
- DiBardino DJ, McKenzie ED, Heinle JS, Su JT, Fraser CD "The Warden procedure for partially anomalous pulmonary venous connection to the superior caval vein.." Cardiol Young. 2004 Feb;14(1):64-7. Pubmed PMID: 15237673
- Booth JH, Bryant R, Powers SC, Ge S, McKenzie ED, Heinle JS, Fraser CD, Morales DL "Transthoracic echocardiography does not reliably predict involvement of the aortic valve in patients with a discrete subaortic shelf.." Cardiol Young. 2010 Jun;20(3):284-9. Pubmed PMID: 20420742
- Doan ML, Mallory GB, Kaplan SL, Dishop MK, Schecter MG, McKenzie ED, Heinle JS, Elidemir O "Treatment of adenovirus pneumonia with cidofovir in pediatric lung transplant recipients.." J. Heart Lung Transplant.. 2007 Sep;26(9):883-9. Pubmed PMID: 17845926
- Morales DL, Braud BE, Price JF, Dreyer WJ, Denfield SW, Clunie SK, Heinle JS, Fraser CD "Use of mechanical circulatory support in pediatric patients with acute cardiac graft rejection.." ASAIO J..;53(6):701-5. Pubmed PMID: 18043151
- Park HK, Heinle JS, Morales DL "Williams syndrome and obstructed total anomalous pulmonary venous return: a previously unreported association.." Ann. Thorac. Surg.. 2012 Jul;94(1):289-91. Pubmed PMID: 22734998
Memberships
- American College of Surgeons
- Fellow
- American College of Cardiology
- Fellow
- American Academy of Pediatrics
- Fellow
- Society of Thoracic Surgeons
- Southern Thoracic Surgical Society
- Sabiston Surgical Society
- Brigham Surgical Society
- Harris County Medical Society
- International Society for Minimally Invasive Cardiac Surgery
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