Joshua Anthony Keefe
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Joshua Anthony Keefe
Medical Scientist Training Program (MD/PhD)
Positions
- Medical Scientist Training Program (MD/PhD)
-
Baylor College of Medicine
Houston, TX US
- GS4
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Development, Disease Models & Therapeutics
Baylor College of Medicine
Houston, Texas United States
Mentor - Xander Wehrens, M.D., Ph.D.
Education
- BS from University of California-Los Angeles
- 06/2017 - Los Angeles, California United States
- Biomedical Engineering
- PhD from Baylor College of Medicine
- 12/2024 - Houston, Texas United States
- Cardiovascular inflammation and arrhythmia
Selected Publications
- Jian Wang, Jangling Song, Li Ni, Xander Wehrens "Immune Cells and Arrhythmias." Cardiovasc Res.. 2025 Feb 12; Pubmed PMID: 39937651
- Keefe JA, Navarro-Garcia JA, Ni L, Reilly S, Dobrev D, Wehrens XHT "In-depth characterization of a mouse model of postoperative atrial fibrillation." J Cardiovasc Aging. 2022 Jul 19;2(40) Pubmed PMID: 36337729
- Keefe, Joshua Anthony. Huang, Shih-Jen. Huan, Tianxao. Mendelson, Michael. Yao, Chen. Madhur, Meena S. Levy, Daniel "Evidence for a Causal Role of the SH2B3-B2M Axis in Blood Pressure Regulation." Hypertension. 2019;73:497-503. Pubmed PMID: 30624993
- Chen Yao, George Chen, Ci Song, Joshua Keefe...Daniel Levy "Genome-wide Association Study of Plasma Proteins Identifies Putatively Causal Genes, Proteins, and Pathways for Cardiovascular Disease." Nature Communications. 2018;9 Pubmed PMID: 30111768
- Keefe J, Yao C, Hwang SJ, Courchesne P, Lee GY, Dupuis J, Mizgerd JP, O'Connor G, Washko GR, Cho MH, Silverman EK, Levy D "An Integrative Genomic Strategy Identifies sRAGE as a Causal and Protective Biomarker of Lung Function." Chest. 2022 Jan;161(1):76-84. Pubmed PMID: 34237330
Funding
- McNair MD/PhD Scholar McNair Medical Institute at The Robert and Janice McNair Foundation
- Macrophage-Mediated Interleukin-6 Signaling Drives Ryanodine Receptor-2 Calcium Leak in Postoperative Atrial Fibrillation - #1F30HL172431 Grant funding from NIH/NHLBI
Intellectual Property
- Design Patent #62/483,221 (Approved)
- Co Inventors: Kamei, Daniel Takashi. Wu, Benjamin Ming. Pereira, David Yuan. Wu, Chloe Michelle. Yee, Matthew Foosing. Keefe, Joshua Anthony. Pearce, Christina Caroline. Dailamy, Amir Adam. Wong, Vincent K. Le, Nguyen Khoi
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