Kristine Marie McDermott, B.S., M.S., PhD.
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Kristine Marie McDermott, B.S., M.S., PhD.
Postdoctoral Associate
Positions
- Postdoctoral Associate
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Pediatrics - Nutrition
Baylor College of Medicine
- Research Associate
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College of Osteopathic Medicine
Western University of Health Sciences
Pomona, California United States
- Teaching Assistant
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Rutgers University
Education
- PhD from Rutgers University
- 01/2021 - New Brunswick, New Jersey United States
- Neuroscience
- MS from Western University of Health Sciences
- 08/2015 - Pomona, California United States
- Biomedical Sciences
- BS from Cal Poly Pomona
- 05/2013 - Pomona, California United States
- Animal Sciences/Pre-Vet
Selected Publications
- Conde K, Fang S, Xu Y "Unraveling the serotonin saga: from discovery to weight regulation and beyond - a comprehensive scientific review.." Cell Biosci. 2023 Aug 7; Pubmed PMID: 37550777
- Kristie M Conde and Troy A Roepke "17β-Estradiol Increases Arcuate KNDy Neuronal Sensitivity to Ghrelin Inhibition of the M-Current in Female Mice." Neuroendocrinology .. 2020; Pubmed PMID: 31484184
- Conde K, Kulyk D, Vanschaik A, Daisey S, Rojas C, Wiersielis K, Yasrebi A, Degroat TJ, Sun Y, Roepke TA "Deletion of Growth Hormone Secretagogue Receptor in Kisspeptin Neurons in Female Mice Blocks Diet-Induced Obesity." Biomolecules. 2022; Pubmed PMID: 36291579
- Carolina Fabelo, Jennifer Hernandez, Rachel Chang, Sakara Seng, Natalia Alicea, Sharon Tian, Kristie Conde, Edward J Wagner "Endocannabinoid Signaling at Hypothalamic Steroidogenic Factor-1/Proopiomelanocortin Synapses Is Sex- and Diet-Sensitive." Front Mol Neurosci .. 2018; Pubmed PMID: 29973869
- Ji Liu, Kristie Conde, Peng Zhang, Varoth Lilascharoen, Zihui Xu, Byung Kook Lim, Randy J Seeley, J Julius Zhu, Michael M Scott, Zhiping P Pang "Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus." Neuron. 2017; Pubmed PMID: 29056294
- Kristie Conde, Cecilia Meza, Martin J Kelly, Kevin Sinchak, Edward J Wagner "Estradiol Rapidly Attenuates ORL-1 Receptor-Mediated Inhibition of Proopiomelanocortin Neurons via Gq-Coupled, Membrane-Initiated Signaling." Neuroendocrinology .. 2016; Pubmed PMID: 26765570
- Samantha Adams, Kimberly Wiersielis, Ali Yasrebi, Kristie Conde, Laura Armstrong, Grace L Guo, Troy A Roepke "Sex- and age-dependent effects of maternal organophosphate flame-retardant exposure on neonatal hypothalamic and hepatic gene expression." Reprod Toxicol .. 2020; Pubmed PMID: 32360330
- Kristie Conde, Carolina Fabelo, William C Krause, Robert Propst, Jordan Goethel, Daniel Fischer, Jin Hur, Cecilia Meza, Holly A Ingraham, Edward J Wagner "Testosterone Rapidly Augments Retrograde Endocannabinoid Signaling in Proopiomelanocortin Neurons to Suppress Glutamatergic Input from Steroidogenic Factor 1 Neurons via Upregulation of Diacylglycerol Lipase-α." Neuroendocrinology .. 2017; Pubmed PMID: 27871072
- Gwyndolin M Vail, Sabrina N Walley, Ali Yasrebi, Angela Maeng, Kristie M Conde, Troy A Roepke "The interactions of diet-induced obesity and organophosphate flame retardant exposure on energy homeostasis in adult male and female mice." J Toxicol Environ Health A .. 2020; Pubmed PMID: 32546061
- Yanlin He, Xing Cai, Hailan Liu, Krisitine M Conde 1, Pingwen Xu, Yongxiang Li, Chunmei Wang, Meng Yu, Yang He, Hesong Liu, Chen Liang, Tingting Yang, Yongjie Yang, Kaifan Yu, Julia Wang, Rong Zheng, Feng Liu, Zheng Sun, Lora Heisler,... Gang Shu, Yong Xu "5-HT recruits distinct neurocircuits to inhibit hunger-driven and non-hunger-driven feeding." Mol Psychiatry. 2021 Jul; Pubmed PMID: 34290371
- Huang Z, Liu L, Zhang J, Conde K, Phansalkar J, Li Z, Yao L, Xu Z, Wang W, Zhou J, Bi G, Wu F, Seeley RJ, Scott MM, Zhan C, Pang ZP, Liu J "Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism.." Sci Adv. 2022; Pubmed PMID: 35675406
- Vail GM, Walley SN, Yasrebi A, Maeng A, Degroat TJ, Conde KM, Roepke TA "Implications of estrogen receptor alpha (ERa) with the intersection of organophosphate flame retardants and diet-induced obesity in adult mice." J Toxicol Environ Health A. 2022; Pubmed PMID: 35045790
- Vail GM, Walley SN, Yasrebi A, Maeng A, Degroat TJ, Conde KM, Roepke TA "Implications of peroxisome proliferator-activated receptor gamma (PPARY) with the intersection of organophosphate flame retardants and diet-induced obesity in adult mice." J Toxicol Environ Health A. 2022; Pubmed PMID: 35000574
- Yu M, Bean JC, Liu H, He Y, Yang Y, Cai X, Yu K, Pei Z, Liu H, Tu L, Conde KM, Wang M, Li Y, Yin N, Zhang N, Han J, Scarcelli NA, Xu P, He Y, Xu Y, Wang C "SK3 in POMC neurons plays a sexually dimorphic role in energy and glucose homeostasis." Cell Biosci. 2022 Oct 9; Pubmed PMID: 36210455
- Tu L, Zhang N, Conde KM, Bean JC, Wang C, Xu Y "Free-floating Immunostaining of Mouse Brains." J Vis Exp. 2021 Oct 7; Pubmed PMID: 34694284
- Wiersielis KR, Adams S, Yasrebi A, Conde K, Roepke TA "Maternal exposure to organophosphate flame retardants alters locomotor and anxiety-like behavior in male and female adult offspring.." Horm Behav. 2020 Jun; Pubmed PMID: 32320692
- He Y, Brouwers B, Liu H, Liu H, Lawler K, Mendes de Oliveira E, Lee DK, Yang Y, Cox ARZh, Keogh JM, Henning E, Bounds R, Perdikari A, Ayinampudi V, Wang C, Yu M, Tu L,KM, Potts C, Bea ang N, Yin N, Han J, Scarcelli NA, Yan Z, Cond "Human loss-of-function variants in the serotonin 2C receptor associated with obesity and maladaptive behavior." Nat. Med.. 2022; Pubmed PMID: 36536256
- Tu L, Bean JC, He Y, Liu H, Yu M, Liu H, Zhang N, Yin N, Han J, Scarcelli NA, Conde KM, Wang M, Li Y, Feng B, Gao P, Cai ZL, Fukuda M, Xue M, Tong Q, Yang Y, Liao L, Xu J, Wang C, He Y, Xu Y "Anoctamin 4 channel currents activate glucose-inhibited neurons in the mouse ventromedial hypothalamus during hypoglycemia.." J Clin Invest.. 2023 Jul 17; Pubmed PMID: 37261917
- Pei Z, He Y, Bean JC, Yang Y, Liu H, Yu M, Yu K, Hyseni I, Cai X, Liu H, Qu N, Tu L, Conde KM, Wang M, Li Y, Yin N, Zhang N, Han J, Potts CH, Scarcelli NA, Yan Z, Xu P, Wu Q, He Y, Xu Y, Wang C. "Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance.." Front Endocrinol. 2022; Pubmed PMID: 36120438
- Conde KM, Wong H, Fang S, Li Y, Yu M, Deng Y, Liu Q, Fang X, Wang M, Shi Y, Ginnard OZ, Yang Y, Tu L, Liu H, Liu H, Yin N, Bean JC, Han J, Burt ME, Jossy SV, Yang Y, Tong Q, Arenkiel BR, Wang C, He Y, Xu Y "5-HT Neurons Integrate GABA and Dopamine Inputs to Regulate Meal Initiation.." bioRxiv. 2024; Pubmed PMID: 38746314
- Liu H, Qu N, Gonzalez NV, Palma MA, Chen H, Xiong J, Choubey A, Li Y, Li X, Yu M, Liu H, Tu L, Zhang N, Yin N, Conde KM, Wang M, Bean JC, Han J, Scarcelli NA, Yang Y, Saito K, Cui H, Tong Q, Sun Z, Wang C, Cai X, Lu L, He Y, Xu Y "A light-responsive neural circuit suppresses feeding.." J Neurosci. 2024; Pubmed PMID: 38897723
- Liu H, He Y, Liu H, Brouwers B, Yin N, Lawler K, Keogh JM, Henning E, Lee DK, Yu M, Tu L, Zhang N, Conde KM, Han J, Yan Z, Scarcelli NA, Liao L, Xu J, Tong Q, Zheng H, Sun Z, Yang Y, Wang C, He Y, Farooqi IS, Xu Y "Neural circuits expressing the serotonin 2C receptor regulate memory in mice and humans." Sci Adv. 2024; Pubmed PMID: 38941473
Memberships
- Society for Behavioral Neuroendocrinology
- Member
- Society for Endocrinology
- Member (10/2020 - 10/2021)
- The Obesity Society
- Member & Trainee Representative of Neuroscience Section
Funding
- 5-HT Neurons and Meal Regulation - #1F32DK134121-01A1 Grant funding from NIH-NIDDK
- Postdoctoral Fellowship CNRC
- Louis Bevier Completion Fellowship Rutgers University
- This award is given to students who have demonstrated excellence in presentations, posters, publications, intellectual merit, and a feasible plan to complete dissertation.
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