Email

miaohsuc@bcm.edu

Positions

Associate Professor

Pediatrics-Nutrition
Baylor College of Medicine
Houston, TX US

Addresses

Children's Nutrition Research Center (Lab)

Room: CNRC-10018
Houston, TX 77030
United States

Children's Nutrition Research Center (Office)

Room: CNRC-10018
Houston, TX 77030
United States

Education

Postdoctoral Fellowship at University Of California, San Francisco

06/2010 - San Francisco, California United States

PhD from University Of Texas At Austin

12/2002 - Austin, Texas United States

Professional Interests

• Developmental biology, adipose tissue biology, stem/progenitor cells

Professional Statement

Dysregulation of the development of progenitor cells during fetal development, early childhood, or even adulthood can significantly contribute to congenital malformations and the development of chronic diseases, such as heart disease, obesity, and type II diabetes. My research program focuses on understanding the origin of adipocytes, developing novel strategies to trace and isolate different types of adipocyte progenitor cells, and investigating the nutritional control of the development and function of these progenitor cells under physiological and pathological conditions.

Websites

Selected Publications

• Kaneko K, Fu Y, Lin HY, Cordonier ELStypulkowski E, Feng Q, Joseph I, Farrell V, Flores J, Yu S, Sakamori R, Sun J, Bandyopadhyay S, Das S, Dobrowolski R, Bonder EM, Chen MH, Gao N. "Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes.." J Biol Chem.. 2021 Mar 1;100488. Pubmed PMID: 33662399
• Mo Q, Salley J, Roshan T, Baer LA, May FJ, Jaehnig EJ, Lehnig AC, Guo X, Tong Q, Nuotio-Antar AM, Shamsi F, Tseng YH, Stanford KI, Chen MH. ". Identification and characterization of a supraclavicular brown adipose tissue in mice.." JCI Insight. 2017 Jun 2;2(11):e93166. Pubmed PMID: 28570265
• Nosavanh L, Yu DH, Jaehnig EJ, Tong Q, Shen L, Chen MH. "Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development.." Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5069-74. Pubmed PMID: 25848030
• 2. Chen M-H, Wilson CW, Li YJ, Law KK, Lu C-S, Gacayan R, Zhang X, Hui C-C, Chuang P-T "Cilium independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.." Genes Dev. 2009;23(16):1901-1928.