Rammurti T Kamble, M.D.

Picture

Rammurti T Kamble, M.D.

Professor

Phone

713-441-1450

Email

kamble@bcm.edu

Positions

Professor: Center for Gene Therapy
Baylor College of Medicine
Houston, TX US

Member: Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States

Addresses

Houston Methodist Hospital (Clinic)
: 6565 Fannin St., Suite 800
Houston, TX 77030
United States
Phone: (713) 441-1450

Education

MD from P.J. Nehru Medical College: Raipur, India

Residency at University of Tennessee College of Medicine: Memphis, TN; Internal Medicine

Fellowship at University of Oklahoma Health Science Center: Oklahoma City, OK; Hematology and Oncology

Fellowship at All India Institute of Medical Sciences: New Delhi, India; Hematology and Oncology

Fellowship at University of Arkansas Medical School: Little Rock, AR; Hematology and Oncology

Fellowship at New York Hospital - Cornell Medical Center: New York City, NY; Hematology

Certifications

American Board of Internal Medicine

American Board of Internal Medicine, Medical Oncology

Professional Statement

Dr. Kamble is Professor of Medicine in Hematology-Oncology, Cell and Gene Therapy, Baylor College of Medicine and Methodist Hospital, Houston, TX. He graduated from Ravi Shankar University, India in 1986 with a gold medal. He obtained postgraduate residency training from prestigious Postgraduate Institute of Medical Science and Research (PGIMER) Chandigarh, India and his fellowship training in Hematology-Oncology from All India Institute of Medical Sciences (AIIMS), New Delhi. He was junior faculty in the AIIMS before joining MAMC, New Delhi University as Assistant Professor of Medicine. Between 1997 and 2001, he completed his residency and fellowship training in Internal Medicine and Hematology-Oncology from University of Tennessee and University of Arkansas for Medical Sciences respectively. He has served as Assistant Professor of Medicine and Associate director of Hematology-Oncology fellowship program at Oklahoma University Health Sciences Center (OUHSC). Dr. Kamble is primarily interested in hematologic malignancies including multiple myeloma and hematopoietic stem cell transplantation. He was conferred Union against cancer (ICRETT, Geneva) award in 1994 to study molecular aspect of chronic myelogenous leukemia and bone marrow transplant in Hammersmith hospital, London and Central Science and Industrial Research (CSIR) award in 1995 to study stem cell transplantation in Cornell University, New York. Dr. Kamble is board certified in Internal Medicine and Medical Oncology. He has published extensively in prestigious journals including, Blood, Biology of Bone marrow transplantation and Journal of Clinical Oncology and regularly reviews manuscripts for Blood, Biology of bone marrow transplantation and Bone marrow transplant. Dr. Kamble's clinical interests are in innovative reduced conditioning protocols, in vivo T-cell depletion and novel approaches to reduce and treat graft-versus-host disease.

Websites

VIICTR Publications List

Hematology and Oncology

Center for Cell and Gene Therapy

Selected Publications

Kamble RT, Guo S, Ramos CA, Carrum G "Acute gout at engraftment following hematopoietic transplantation.." Am. J. Hematol.. 2011 Nov;86(11):961-2. Pubmed PMID: 21948346
Kurkjian C, Patel S, Kamble R, Dunn ST, Kern W, Kharfan-Dabaja MA "Acute promyelocytic leukemia and constitutional trisomy 21.." Cancer Genet. Cytogenet.. 2006 Mar;165(2):176-9. Pubmed PMID: 16527614
Hamadani M, Saber W, Ahn KW, Carreras J, Cairo MS, Fenske TS, Gale RP, Gibson J, Hale GA, Hari PN, Hsu JW, Inwards DJ, Kamble RT, Klein A, Maharaj D, Marks DI, Rizzieri DA, Savani BN, Schouten HC, Waller EK, Wirk B, Lazarus HM "Allogeneic hematopoietic cell transplantation for chemotherapy-unresponsive mantle cell lymphoma: a cohort analysis from the center for international blood and marrow transplant research.." Biol. Blood Marrow Transplant.. 2013 Apr;19(4):625-31. Pubmed PMID: 23333532
Kamble R, Raju GM, Kumar L, Kochupillai V "Blood stem cell transplantation: current concepts.." Indian J. Med. Res.. 1997 Jan;105:41282. Pubmed PMID: 9029828

Savoldo B, Ramos CA, Liu E, Mims MP, Keating MJ, Carrum G, Kamble RT, Bollard CM, Gee AP, Mei Z, Liu H, Grilley B, Rooney CM, Heslop HE, Brenner MK, Dotti G "CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients.." J. Clin. Invest.. 2011 May 2;121(5):1822-6. Pubmed PMID: 21540550
Kamble RT, Chang CC, Sanchez S, Carrum G "Central nervous system graft-versus-host disease: report of two cases and literature review.." Bone Marrow Transplant.. 2007 Jan;39(1):49-52. Pubmed PMID: 17099715
Pellett PE, Ablashi DV, Ambros PF, Agut H, Caserta MT, Descamps V, Flamand L, Gautheret-Dejean A, Hall CB, Kamble RT, Kuehl U, Lassner D, Lautenschlager I, Loomis KS, Luppi M, Lusso P, Medveczky PG, Montoya JG, Mori Y, Ogata M, Pritchett JC, Rogez S, Seto "Chromosomally integrated human herpesvirus 6: questions and answers.." Rev. Med. Virol.. 2012 May;22(3):144-55. Pubmed PMID: 22052666
Dunn T, Allen R, Bates F, Kurkjian C, Kamble R, Kharfan-Dabaja M "Cytogenetic changes associated with myelodysplastic syndrome affecting bone marrow engraftment analysis.." J Mol Diagn. 2006 May;8(2):288-94. Pubmed PMID: 16645218
Kamble RT, Hamadani M, Selby GB "Delayed myeloid engraftment due to vancomycin in allogeneic haematopoietic stem cell transplant recipients.." J. Antimicrob. Chemother.. 2006 Apr;57(4):795-6. Pubmed PMID: 16476723
Kamble R, Rosenzweig T "Diffuse pulmonary parenchymal involvement in multiple myeloma: antemortem diagnosis.." Int. J. Hematol.. 2006 Apr;83(3):259-61. Pubmed PMID: 16720559
Ringdén O, Shrestha S, da Silva GT, Zhang MJ, Dispenzieri A, Remberger M, Kamble R, Freytes CO, Gale RP, Gibson J, Gupta V, Holmberg L, Lazarus H, McCarthy P, Meehan K, Schouten H, Milone GA, Lonial S, Hari PN "Effect of acute and chronic GVHD on relapse and survival after reduced-intensity conditioning allogeneic transplantation for myeloma.." Bone Marrow Transplant.. 2012 Jun;47(6):831-7. Pubmed PMID: 21946381
Vogl DT, Wang T, Pérez WS, Stadtmauer EA, Heitjan DF, Lazarus HM, Kyle RA, Kamble R, Weisdorf D, Roy V, Gibson J, Ballen K, Holmberg L, Bashey A, McCarthy PL, Freytes C, Maharaj D, Maiolino A, Vesole D, Hari P "Effect of obesity on outcomes after autologous hematopoietic stem cell transplantation for multiple myeloma.." Biol. Blood Marrow Transplant.. 2011 Dec;17(12):1765-74. Pubmed PMID: 21624486
Wen J, Feng Y, Huang W, Chen H, Liao B, Rice L, Preti HA, Kamble RT, Zu Y, Ballon DJ, Chang CC "Enhanced antimyeloma cytotoxicity by the combination of arsenic trioxide and bortezomib is further potentiated by p38 MAPK inhibition.." Leuk. Res.. 2010 Jan;34(1):85-92. Pubmed PMID: 19608275
Kharfan-Dabaja MA, Patel SA, Osunkoya AO, Kojouri K, Kamble R, Yang J, Hashmi M, Ozer H, Selby GB "Expression of the vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukemia: incidence and feasibility of immunohistochemical staining.." Clin Lab Haematol. 2006 Aug;28(4):254-8. Pubmed PMID: 16898965
Kamble R, Kochupillai V, Sharma A, Kumar L, Thulkar S, Sharma MC, Mittal S "Granulocytic sarcoma of uterine cervix as presentation of acute myeloid leukemia: a case report and review of literature.." J. Obstet. Gynaecol. Res.. 1997 Jun;23(3):261-6. Pubmed PMID: 9255039
Duval M, Klein JP, He W, Cahn JY, Cairo M, Camitta BM, Kamble R, Copelan E, de Lima M, Gupta V, Keating A, Lazarus HM, Litzow MR, Marks DI, Maziarz RT, Rizzieri DA, Schiller G, Schultz KR, Tallman MS, Weisdorf D "Hematopoietic stem-cell transplantation for acute leukemia in relapse or primary induction failure.." J. Clin. Oncol.. 2010 Aug 10;28(23):3730-8. Pubmed PMID: 20625136
Vu T, Carrum G, Hutton G, Heslop HE, Brenner MK, Kamble R "Human herpesvirus-6 encephalitis following allogeneic hematopoietic stem cell transplantation.." Bone Marrow Transplant.. 2007 Jun;39(11):705-9. Pubmed PMID: 17401392
Kamble RT, Bollard C, Demmler G, LaSala PR, Carrum G "Human metapneumovirus infection in a hematopoietic transplant recipient.." Bone Marrow Transplant.. 2007 Oct;40(7):699-700. Pubmed PMID: 17660843
Fenske TS, Hari PN, Carreras J, Zhang MJ, Kamble RT, Bolwell BJ, Cairo MS, Champlin RE, Chen YB, Freytes CO, Gale RP, Hale GA, Ilhan O, Khoury HJ, Lister J, Maharaj D, Marks DI, Munker R, Pecora AL, Rowlings PA, Shea TC, Stiff P, Wiernik PH, Winter JN, Ri "Impact of pre-transplant rituximab on survival after autologous hematopoietic stem cell transplantation for diffuse large B cell lymphoma.." Biol. Blood Marrow Transplant.. 2009 Nov;15(11):1455-64. Pubmed PMID: 19822306
Hamadani M, Saber W, Ahn KW, Carreras J, Cairo MS, Fenske TS, Gale RP, Gibson J, Hale GA, Hari PN, Hsu JW, Inwards DJ, Kamble RT, Klein A, Maharaj D, Marks DI, Rizzieri DA, Savani BN, Schouten HC, Waller EK, Wirk B, Laport GG, Montoto S, Maloney DG, Lazar "Impact of Pretransplantation Conditioning Regimens on Outcomes of Allogeneic Transplantation for Chemotherapy-Unresponsive Diffuse Large B Cell Lymphoma and Grade III Follicular Lymphoma.." Biol. Blood Marrow Transplant.. 2013 May;19(5):746-53. Pubmed PMID: 23380340
Kamble RT, Hamadani M, Selby GB "Increased mean corpuscular volume after autologous hematopoietic stem cell transplantation: incidence and significance.." Biol. Blood Marrow Transplant.. 2006 Jan;12(1):111-2. Pubmed PMID: 16399575
Kamble RT, Selby GB, Mims M, Kharfan-Dabaja MA, Ozer H, George JN "Iron overload manifesting as apparent exacerbation of hepatic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.." Biol. Blood Marrow Transplant.. 2006 May;12(5):506-10. Pubmed PMID: 16635785
Kamble R, Mims M "Iron-overload in long-term survivors of hematopoietic transplantation.." Bone Marrow Transplant.. 2006 Apr;37(8):805-6. Pubmed PMID: 16518421
Buchbinder D, Nugent DJ, Brazauskas R, Wang Z, Aljurf MD, Cairo MS, Chow R, Duncan C, Eldjerou LK, Gupta V, Hale GA, Halter J, Hayes-Lattin BM, Hsu JW, Jacobsohn DA, Kamble RT, Kasow KA, Lazarus HM, Mehta P, Myers KC, Parsons SK, Passweg JR, Pidala J, Red "Late effects in hematopoietic cell transplant recipients with acquired severe aplastic anemia: a report from the late effects working committee of the center for international blood and marrow transplant research.." Biol. Blood Marrow Transplant.. 2012 Dec;18(12):1776-84. Pubmed PMID: 22863842
Kamble RT, Hjortsvang E, Selby GB "Leukemia burden and outcome of allogeneic transplant in acute myelogenous leukemia.." Biol. Blood Marrow Transplant.. 2006 Jun;12(6):691-2. Pubmed PMID: 16737944
Kamble R, Wilson CS, Fassas A, Desikan R, Siegel DS, Tricot G, Anderson P, Sawyer J, Anaissie E, Barlogie B "Malignant pleural effusion of multiple myeloma: prognostic factors and outcome.." Leuk. Lymphoma. 2005 Aug;46(8):1137-42. Pubmed PMID: 16085553
Hamadani M, Kharfan-Dabaja M, Kamble R, Kern W, Ozer H "Marginal zone B-cell lymphoma of the uterus: a case report and review of the literature.." J Okla State Med Assoc. 2006 Apr;99(4):154-6. Pubmed PMID: 16703935
Kamble R, Pant S, Selby GB, Kharfan-Dabaja MA, Sethi S, Kratochvil K, Kohrt N, Ozer H "Microbial contamination of hematopoietic progenitor cell grafts-incidence, clinical outcome, and cost-effectiveness: an analysis of 735 grafts.." Transfusion. 2005 Jun;45(6):874-8. Pubmed PMID: 15934984
Kamble RT "Orthotopic heart transplant facilitated autologous hematopoietic stem cell transplantation in light-chain amyloidosis.." Methodist DeBakey Cardiovasc J. 2012 Jul;8(3):17-8. Pubmed PMID: 23227280
Shafer JA, Heslop HE, Brenner MK, Carrum G, Wu MF, Liu H, Ahmed N, Gottschalk S, Kamble R, Leung KS, Myers GD, Bollard CM, Krance RA "Outcome of hematopoietic stem cell transplant as salvage therapy for Hodgkin's lymphoma in adolescents and young adults at a single institution.." Leuk. Lymphoma. 2010 Apr;51(4):664-70. Pubmed PMID: 20367182
Sharma A, Kamble R, Kumar L, Bhargava B, Biswal BM, Kochupillai V "Palliative treatment of malignant pericardial effusion: report of two cases and a review of the literature.." Support Care Cancer. 1996 Jul;4(4):317-9. Pubmed PMID: 8829313
Ballen K, Mendizabal AM, Cutler C, Politikos I, Jamieson K, Shpall EJ, Dey BR, Attar E, McAfee S, Delaney C, McCarthy P, Ball ED, Kamble R, Avigan D, Maziarz RT, Ho VT, Koreth J, Alyea E, Soiffer R, Wingard JR, Boussiotis V, Spitzer TR, Antin JH "Phase II Trial of Parathyroid Hormone after Double Umbilical Cord Blood Transplantation.." Biol. Blood Marrow Transplant.. 2012 Dec;18(12):1851-8. Pubmed PMID: 22766223
Hari PN, Majhail NS, Zhang MJ, Hassebroek A, Siddiqui F, Ballen K, Bashey A, Bird J, Freytes CO, Gibson J, Hale G, Holmberg L, Kamble R, Kyle RA, Lazarus HM, LeMaistre CF, Loberiza F, Maiolino A, McCarthy PL, Milone G, Omondi N, Reece DE, Seftel M, Trigg "Race and outcomes of autologous hematopoietic cell transplantation for multiple myeloma.." Biol. Blood Marrow Transplant.. 2010 Mar;16(3):395-402. Pubmed PMID: 19922808
Kamble RT, Sethi S, Selby GB "Re: failure to engraft after autologous stem cell transplantation: possible therapeutic role of cyclosporine.." Biol. Blood Marrow Transplant.. 2005 Jan;11(1):74. Pubmed PMID: 15625547
Bhat SP, Sundaram P, Kamble RT, Joshi JM "Recurrent respiratory papillomatosis.." Indian J Chest Dis Allied Sci.;42(1):35-7. Pubmed PMID: 10851821
Armor JF, Fazili J, Toubia N, Kern W, Kamble R, Kharfan-Dabaja MA "Remission of natural-killer cell lymphoma of the liver with anti-hepatitis C therapy.." Am. J. Hematol.. 2005 Mar;78(3):212-5. Pubmed PMID: 15726605
Kamble R, Oholendt M, Carrum G "Rituximab responsive refractory acute graft-versus-host disease.." Biol. Blood Marrow Transplant.. 2006 Nov;12(11):1201-2. Pubmed PMID: 17085314
Michaelis LC, Saad A, Zhong X, Le-Rademacher J, Freytes CO, Marks DI, Lazarus HM, Bird JM, Holmberg L, Kamble RT, Kumar S, Lill M, Meehan KR, Saber W, Schriber J, Tay J, Vogl DT, Wirk B, Savani BN, Gale RP, Vesole DH, Schiller GJ, Abidi M, Anderson KC, Ni "Salvage Second Hematopoietic Cell Transplantation in Myeloma.." Biol. Blood Marrow Transplant.. 2013 May;19(5):760-6. Pubmed PMID: 23298856
Danner-Koptik KE, Majhail NS, Brazauskas R, Wang Z, Buchbinder D, Cahn JY, Dilley KJ, Frangoul HA, Gross TG, Hale GA, Hayashi RJ, Hijiya N, Kamble RT, Lazarus HM, Marks DI, Reddy V, Savani BN, Warwick AB, Wingard JR, Wood WA, Sorror ML, Jacobsohn DA "Second malignancies after autologous hematopoietic cell transplantation in children.." Bone Marrow Transplant.. 2013 Mar;48(3):363-8. Pubmed PMID: 22964594
Thomas P, Keightley A, Kamble R, Gunasekera N, Johnson MR "Sigmoid sinus thrombosis presenting with posterior alexia in a patient with Behçet's disease and polycythaemia: a case report.." 2008;2:175. Pubmed PMID: 18500981
Raina V, Kamble R, Tanwar R, Singh SP, Sharma S "Spinal ganglioneuroblastoma--complete response to chemotherapy alone.." Postgrad Med J. 1993 Sep;69(815):746-8. Pubmed PMID: 8255850
Kamble RT, Tin-U CK, Carrum G "Successful mobilization and transplantation of filgrastim mobilized hematopoietic stem cells in sickle cell-hemoglobin C disease.." Bone Marrow Transplant.. 2006 Jun;37(11):1065-6. Pubmed PMID: 16708064
Kurkjian C, Armor JF, Kamble R, Ozer H, Kharfan-Dabaja MA "Symptomatic metastases to the pituitary infundibulum resulting from primary breast cancer.." Int. J. Clin. Oncol.. 2005 Jun;10(3):191-4. Pubmed PMID: 15990968
El Fakih R, Obi GA, Scholoff A, Carrum G, Kamble RT "Systemic effects of oral budesonide in hematopoietic transplant: implications of drug interaction with azoles.." Bone Marrow Transplant.. 2012 Oct;47(10):1370-1. Pubmed PMID: 22327133
Kamble R, Ward K "The foot and systemic disease. Differential diagnoses.." Clin Podiatr Med Surg. 1998 Oct;15(4):739-64. Pubmed PMID: 9917988
Kamble RT, Clark DA, Leong HN, Heslop HE, Brenner MK, Carrum G "Transmission of integrated human herpesvirus-6 in allogeneic hematopoietic stem cell transplantation.." Bone Marrow Transplant.. 2007 Sep;40(6):563-6. Pubmed PMID: 17637686
Kumar S, Zhang MJ, Li P, Dispenzieri A, Milone GA, Lonial S, Krishnan A, Maiolino A, Wirk B, Weiss B, Freytes CO, Vogl DT, Vesole DH, Lazarus HM, Meehan KR, Hamadani M, Lill M, Callander NS, Majhail NS, Wiernik PH, Nath R, Kamble RT, Vij R, Kyle RA, Gale "Trends in allogeneic stem cell transplantation for multiple myeloma: a CIBMTR analysis.." Blood. 2011 Aug 18;118(7):1979-88. Pubmed PMID: 21690560