Samantha Paige Tippen

Assistant Professor

Email

samantha.tippen@bcm.edu

Positions

Assistant Professor: Anatomy Core Services
Baylor College of Medicine
Houston, US

Education

PhD from Indiana University School of Medicine: 05/2023 - Indianapolis, Indiana United States; Anatomy & Cell Biology

MS from Sam Houston State University: 05/2014 - Huntsville, Texas United States; Forensic Science

BA from University of North Texas: 05/2012 - Denton, Texas United States; Anthropology

BS from University of North Texas: 05/2012 - Denton, Texas United States; Chemistry

Honors & Awards

NIH F31 Predoctoral Fellowship: Chronic kidney disease effects on cortical bone porosity and mechanics with age (F31-DK130603); NIH - NIDDK (07/2021 - 05/2023)

Selected Publications

Tippen SP, Noonan ML, Ni P, Metzger CE, Swallow EA, Sacks SA, Chen NX, Thompson WR, Prideaux M, Atkins GA, Moe SM, Allen MR, White KE "Age and sex effects on FGF23-mediated response to mild phosphate challenge." Bone. 2021;
Morita K, Kantarjian H, Wang F, Yan Y, Bueso-Ramos C, Sasaki K, Issa GC, Wang S, Jorgensen J, Song X, Zhang J, Tippen S, Thornton R, Coyle M, Little L, Gumbs C, Pemmaraju N, Daver N, DiNardo C, Konopleva M, Andreef M, Ravandi F, ... Futreal A, Takahashi K "Clearance of somatic mutations at remission and the risk of relapse in acute myeloid leukemia." J Clin Oncol. 2018;
Takahashi K, Hu B, Wang F, Yan Y, Kim E, Vitale C, Patel KP, Strati P, Gumbs C, Little L, Tippen S, Song X, Zhang J, Jain N, Thompson P, Garcia-Manero G, Kantarjian H, Estrov Z, Do K-A, Keating M, Burger JA, Ferrajoli A, Futreal PA, Wierda WG "Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide." Blood. 2018;
Reuben A, ...Tippen S, ... Moran C, Kalhor N, Zhang J, Scheet P, Vaporciyan AA, Sepesi B, Gibbons DL, Robins H, Hwu P, Heymach JV, Sharma P, Allison JP, Baladandayuthapani V, Lee JJ, Davis MM, Wistuba II, Futreal PA, Zhang J "Comprehensive T cell repertoire characterization of non-small cell lung cancer." Nat Commun. 2020;

Takahashi K, Wang F, Kantarjian H, Song X, Patel K, Neelapu S, Gumbs C, Little L, Tippen S, Thornton R, DiNardo CD, Ravandi F, Bueso-Ramos C, Zhang J, Wu X, Garcia-Manero G, Futreal PA "Copy number alterations detected as clonal hematopoiesis of indeterminate potential." Blood Advances. 2017;
Swallow EA, Metzger CE, Chen NX, Wallace JM, Tippen SP, Kohler R, Moe SM, Allen MR "Cortical porosity is elevated after a single dose of zoledronate in two rodent models of chronic kidney disease." Bone Reports. 2022;
Metzger CE, Newman CL, Tippen SP, Golemme NT, Chen NX, Moe SM, Allen MR "Cortical porosity occurs at varying degrees throughout the skeleton in rats with chronic kidney disease." Bone Reports. 2022;
Kim ST... Tippen SP, Gumbs C, Neelapu SS, Naing A, Wang L, Diab A, Futreal A, Nurieva R, Daver N "Distinct immunophenotypes of T cells in bronchoalveolar lavage fluid from leukemia patients with immune checkpoint inhibitors-related pulmonary complications." Front Immunol. 2021;
Takahashi K, Wang F, Patel K, Bueso-Ramos CE, Issa GC, Song X, Zhang J, Tippen S, Little L, Gumbs C, Ravandi F, Kadia TM, Daver NG, Dinardo CD, Konopleva M, Andreeff M, Cortes JE, Jabbour E, Futreal A, Kantarjian HM "Distinct patterns of somatic mutation clearance and association with clinical outcome in patients with AML." J Clin Oncol. 2017;
Noonan ML, Clinkenbeard EL, Ni P, Swallow EA, Agoro R, Tippen SP, Allen MR, White KE "Erythropoietin and a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHDi) lowers FGF23 in a model of chronic kidney disease (CKD)." Physiol Rep. 2020;
Morita K, Wang F, Patel K, Bueso-Ramos C, Zhar AA, Gumbs C, Little L, Tippen S, Thornton R, Coyle M, Zhang J, Song X, Mendoza M, Wu C-J, Kornblau S, DiNardo C, Ravandi F, Garcia-Manero G, Jabbour E, Andreeff M, Kantarjian H, ... Futreal A, Takahashi K "Genomic landscape of mixed phenotype acute leukemia (MPAL)." Cl Lymph Myelom Leuk. 2017;
Takahashi K, Wang F, Morita K, Yan Y, Hu P, Zhao P, Zhar AA, Wu C, Gumbs C, Little L, Tippen S, ... Futreal A "Integrative genomic analysis of adult mixed phenotype acute leukemia (MPAL) delineates lineage associated molecular subtypes." Nat Commun. 2018;
Hillman RT, Celestino J, Terranova C, Beird HC, Gumbs C, Little L, Nguyen T, Thornton R, Tippen S, Zhang J, Lu KH, Gershenson DM, Rai K, Broaddus RR, Futreal PA "KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary." Nat Commun. 2018;
Tippen S, Thornton RL, Kadara H, Scheet P, Roarty E, Ostrin EJ, Wang X, Carter BW, Antonoff MB, Zhang J, Vaporciyan AA, Pass H, Swisher SG, Heymach JV, Lee JJ, Wistuba II, Hong WK, Futreal PA, Su D, Zhang J "Multi-region exome sequencing reveals genomic evolution from preneoplasia to lung adenocarcinoma." Nat Commun. 2019;
Metzger CE, Swallow EA, Stacey AJ, Tippen SP, Hammond M, Chen N, Moe SM, Allen MR "Reversing cortical porosity: Cortical pore infilling in preclinical models of chronic kidney disease." Bone. 2021;
Mitra A, Andrews MC, Roh W, Petaccia De Macedo M, Hudgens CW, Carapeto F, Reuben A, Wang F, Mao X, Song X, Wani K, Tippen S...Futreal PA "Spatially-resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma." Nat Commun. 2020;
Tippen SP, Metzger CE, Swallow EA, Sacks SA, Wallace JM, Allen MR "The combination of aging and chronic kidney disease leads to an exacerbated cortical porosity phenotype." Bone.;
Morita K, Wang F, Yan Y, Burks J, Gumbs C, Little L, Tippen S, Thornton R, Coyle M, Zhang J, Song X, DiNardo C, Jabbour E, Andreeff M, Cortes J, Konopleva M, Patel K, Garcia-Manero G, Kantarjian H, Bueso-Ramos C, Futreal PA, Takahashi K "The landscape of genotype-phenotype correlation in AML." Cl Lymph Myelom Leuk. 2018;