William E Cohn, M.D.
Picture
Positions
- Professor of Surgery
-
Cardiothoracic Transplantation & Circulatory Support
Baylor College of Medicine
- Director, Center for Device Innovation
-
TMC / Johnson & Johnson Innovation
Addresses
- Baylor St. Luke's Medical Center (Hospital)
-
6720 Bertner Avenue
Room: LUKE-2-114A
Houston, TX 77030
United States
- Texas Heart Institute (Office)
-
6770 Bertner Avenue
Suite C355M
Houston, TX 77030
United States
Phone: (832) 355-3000
Cardiothoracic Transplantation and Circulatory Support
Education
- B.S. from Oberlin College
- 01/1982 - Oberlin, OH United States
- M.D. from Baylor College Of Medicine
- 01/1986 - Houston, TX United States
- Internship from Baylor College of Medicine
- 01/1987 - Houston, TX United States
- Chief Residency from Baylor College Of Medicine
- 01/1991 - Houston, TX United States
- Residency from Baylor College Of Medicine
- 01/1990 - Houston, TX United States
- Associate in Cardiothoracic Surg from Beth Israel Hospital, Harvard Medical School
- 01/1994 - Boston, MA United States
- Chief Resident from Baylor College Of Medicine
- 01/1993 - Houston, TX United States
Certifications
- Thoracic Surgery
- American Board of Thoracic Surgery
- General Surgery
- American Board of Surgery
Honors & Awards
- Doctorate in Science- Honorary Degree
- Doctorate in Science- Honorary Degree
- 2013 Edison Award - Silver Medal
- LARIAT® Suture Delivery Device by SentreHEART.
- TVO Inventor’s Recognition Award
- Beth Israel Deaconess Medical Center
- 2014 Inventor of the Year
- The Houston Intellectual Property Law Association
- Earl Bakken Scientific Achievement Award
- Society of Thoracic Surgeons
Professional Interests
- Heart Transplantation
- LVAD
- TAH
- Laparoscopic procedures
- Cardiothoracic Surgery
- Heart Failure
Professional Statement
Dr. William E. Cohn is one of the leaders of the team of experts developing a total artificial heart that will deliver blood by means of continuous flow rather than pulsation. This research has grant support from the National Heart, Lung, and Blood Institute; the John S. Dunn Research Foundation; the Alexander Family Trust; and the McIngvale family Trust. This new artificial heart is smaller, less expensive, and predicted to be more reliable than previous generations of artificial hearts. William E. Cohn currently has 170 active or pending patents for his inventions and is the founder or co-founder of five venture-backed life science startups. In addition, Dr. Cohn is a venture partner at Santé Health Ventures, a venture capital firm focused on capitalizing early-stage life science technology.Websites
LVAD Program at Baylor St. Luke's
Bridging the Gap in Dialysis - TMC News
Billy Cohn- Innovating the Tools of Medicine
Videos
Heart Stop Beating is the story of Billy Cohn & Bud Frazier, two visionary doctors from the Texas Heart Institute, who in March of 2011 successfully replaced a dying man's heart with a 'continuous flow' device they developed, proving that life was possible without a pulse or a heart beat.
Selected Publications
- Tuzun E, Winkler JA, Contreras AL, Sacristan E, Cohn WE "In vivo performance evaluation of the innovamedica pneumatic ventricular assist device.." ASAIO J.. 2012 Mar;58(2):98-102. Pubmed PMID: 22236625
- Rankin JS, Beavan LA, Cohn WE "Technique for aortic valve annuloplasty using an intra-annular hemispherical" frame."." J. Thorac. Cardiovasc. Surg.. 2011 Oct;142(4):933-6. Pubmed PMID: 21377696
- Cohn WE, Frazier OH "The sandwich plug technique: Simple, effective, and rapid closure of a mechanical aortic valve prosthesis at left ventricular assist device implantation.." J. Thorac. Cardiovasc. Surg.. 2011 Aug;142(2):455-7. Pubmed PMID: 21277593
- Gregoric ID, Cohn WE, Frazier OH "Diaphragmatic implantation of the HeartWare ventricular assist device.." J. Heart Lung Transplant.. 2011 Apr;30(4):467-70. Pubmed PMID: 21211994
- Sacristan E, Tuzun E, Winkler JA, Contreras AL, Cohn WE "In vivo performance evaluation of the innovamedica pneumatic ventricular assist device.." Conf Proc IEEE Eng Med Biol Soc. 2011 Aug;2011:1217-20. Pubmed PMID: 22254535
- Frazier OH, Cohn WE "Continuous-flow total heart replacement device implanted in a 55-year-old man with end-stage heart failure and severe amyloidosis.." Tex Heart Inst J. 2012;39(4):542-6. Pubmed PMID: 22949774
- Gonzalez-Stawinski GV, Mountis MM, Cohn WE, Frazier OH "Inflow graft interruption as a simple method for left ventricular assist device removal after successful bridge to recovery.." J Card Surg. 2012 May;27(3):397-9. Pubmed PMID: 22507259
- Tuzun E, Narin C, Gregoric ID, Cohn WE, Frazier OH "Ventricular assist device outflow-graft site: effect on myocardial blood flow.." J. Surg. Res.. 2011 Nov;171(1):71-5. Pubmed PMID: 20605602
- Frazier OH, Tuzun E, Cohn W, Tamez D, Kadipasaoglu KA "Total heart replacement with dual centrifugal ventricular assist devices.." ASAIO J..;51(3):224-9. Pubmed PMID: 15968951
- Gregoric ID, Jacob LP, La Francesca S, Bruckner BA, Cohn WE, Loyalka P, Kar B, Frazier OH "The TandemHeart as a bridge to a long-term axial-flow left ventricular assist device (bridge to bridge).." Tex Heart Inst J. 2008;35(2):125-9. Pubmed PMID: 18612448
- ZEEVI AK, YITZHAK B, COHN W "[Early diagnosis and ecology of leptospirosis; observation in two rural districts.]." Harefuah. 1955 Jun 1;48(11):240-2. Pubmed PMID: 13241883
- COHN WE "[NEW NUCLEOTIDES.]." Bull. Soc. Chim. Biol.. 1964 May 5;46:239-53. Pubmed PMID: 14165541
- COHN WE "5-Ribosyl uracil, a carbon-carbon ribofuranosyl nucleoside in ribonucleic acids.." Biochim. Biophys. Acta. 1959 Apr;32:569-71. Pubmed PMID: 13811055
- Cohn WE, Gregoric ID, Radovancevic B, Frazier OH "A felt plug simplifies left ventricular assist device removal after successful bridge to recovery.." J. Heart Lung Transplant.. 2007 Nov;26(11):1209-11. Pubmed PMID: 18022090
- Gregoric ID, La Francesca S, Myers T, Cohn W, Loyalka P, Kar B, Gemmato C, Frazier OH "A less invasive approach to axial flow pump insertion.." J. Heart Lung Transplant.. 2008 Apr;27(4):423-6. Pubmed PMID: 18374879
- Cohn WE "A transthoracic, left ventricular vent facilitates challenging sternal reentry.." Ann. Thorac. Surg.. 2010 Aug;90(2):679-80. Pubmed PMID: 20667388
- Cohn WE "Abbreviations for enzyme names.." Clin. Chem.. 1972 Jul;18(7):740. Pubmed PMID: 5037922
- Cohn WE, Leonard NJ, Wang SY "Abbreviations for pyrimidine photoproducts.." Photochem. Photobiol.. 1974 Feb;19(2):89-94. Pubmed PMID: 4819958
- COHN WE, VOLKIN E "Acid degradation products of deoxyribonucleic acid.." Biochim. Biophys. Acta. 1957 May;24(2):359-64. Pubmed PMID: 13436438
- Dutt-Ballerstadt R, Evans C, Pillai AP, Gowda A, McNichols R, Rios J, Cohn W "Acute in vivo performance evaluation of the fluorescence affinity sensor in the intravascular and interstitial space in Swine.." J Diabetes Sci Technol. 2013;7(1):35-44. Pubmed PMID: 23439158
- Cohn WE "Advances in surgical treatment of acute and chronic coronary artery disease.." Tex Heart Inst J. 2010;37(3):328-30. Pubmed PMID: 20548814
- Cohn W, Loechleiter F, Weber F "Alpha-tocopherol is secreted from rat liver in very low density lipoproteins.." J. Lipid Res.. 1988 Oct;29(10):1359-66. Pubmed PMID: 3235918
- KHYM JX, COHN WE "Amine-induced cleavage of periodate-oxidized nucleotide residues.." J. Biol. Chem.. 1961 Mar;236:PC9-10. Pubmed PMID: 13755795
- Singhal RP, Cohn WE "Analysis and isolation of nucleosides by ion-exclusion chromatography.." Biochim. Biophys. Acta. 1972 Apr 12;262(4):565-7. Pubmed PMID: 5019071
- Singhal RP, Cohn WE "Analytical separation of nucleosides by anion-exchange chromatography: influence of pH, solvents, temperature, concentration, and flow rate.." Anal. Biochem.. 1972 Feb;45(2):585-99. Pubmed PMID: 5060608
- Cohn W, Radovancevic B, Amir O, Smith R, Smart F, Frazier OH "Aorta-to-left-atrial shunting through a previously performed heterotopic heart transplant: an unusual complication of orthotopic re-transplantation.." J. Heart Lung Transplant.. 2005 Dec;24(12):2290-2. Pubmed PMID: 16364884
- Cohn WE, Gregoric ID, Radovancevic B, Wolf RK, Frazier OH "Atrial fibrillation after cardiac transplantation: experience in 498 consecutive cases.." Ann. Thorac. Surg.. 2008 Jan;85(1):56-8. Pubmed PMID: 18154778
- Cohn WE, Sirois CA, Johnson RG "Atrial fibrillation after minimally invasive coronary artery bypass grafting: A retrospective, matched study.." J. Thorac. Cardiovasc. Surg.. 1999 Feb;117(2):298-301. Pubmed PMID: 9918971
- Cohn WE, Gregoric ID, La Francesca S, Frazier OH "Bedside right ventricular assist device removal in the conscious patient.." Ann. Thorac. Surg.. 2007 Apr;83(4):1556-7. Pubmed PMID: 17383390
- Cohn W "Bioavailability of vitamin E.." Eur J Clin Nutr. 1997 Jan;51:S80-5. Pubmed PMID: 9023489
- Johnson RG, Sirois C, Watkins JF, Thurer RL, Sellke FW, Cohn WE, Kuntz RE, Weintraub RM "CABG after successful PTCA: a case-control study.." Ann. Thorac. Surg.. 1995 Jun;59(6):1391-6. Pubmed PMID: 7771816
- Maslow A, Aronson S, Jacobsohn E, Cohn WE, Johnson RG "Case 6--1999. Off-pump coronary artery bypass graft surgery.." J. Cardiothorac. Vasc. Anesth.. 1999 Dec;13(6):764-81. Pubmed PMID: 10622664
- Singhal RP, Cohn WE "Cation-exclusion chromatography on anion exchangers: application to nucleic acid components and comparison with anion-exchange chromatography.." Biochemistry. 1973 Apr 10;12(8):1532-7. Pubmed PMID: 4573198
- Gregoric ID, Cohn WE, Akay MH, La Francesca S, Myers T, Frazier OH "CentriMag left ventricular assist system: cannulation through a right minithoracotomy.." Tex Heart Inst J. 2008;35(2):184-5. Pubmed PMID: 18612493
- Sellke FW, Wang SY, Stamler A, Johnson RG, Cohn WE, Weintraub RM "Changes in autonomic response of the cerebral circulation after normothermic extracorporeal circulation.." J. Thorac. Cardiovasc. Surg.. 1996 Aug;112(2):450-61. Pubmed PMID: 8751514
- Shalli S, Saeed D, Fukamachi K, Gillinov AM, Cohn WE, Perrault LP, Boyle EM "Chest tube selection in cardiac and thoracic surgery: a survey of chest tube-related complications and their management.." J Card Surg.;24(5):503-9. Pubmed PMID: 19740284
- COHN WE, BOLLUM FJ "Chromatography and desalting of nucleotides with ammonium biocarbonate on anion-exchange columns.." Biochim. Biophys. Acta. 1961 Apr 15;48:588-90. Pubmed PMID: 13694488
- Gregoric ID, Bruckner BA, Jacob L, Kar B, Cohn WE, La Francesca S, Frazier OH "Clinical experience with sternotomy versus subcostal approach for exchange of the HeartMate XVE to the HeartMate II ventricular assist device.." Ann. Thorac. Surg.. 2008 May;85(5):1646-9. Pubmed PMID: 18442556
- Sellke FW, Chu LM, Cohn WE "Current state of surgical myocardial revascularization.." Circ. J.. 2010 May 25;74(6):1031-7. Pubmed PMID: 20467145
- Ross MJ, Sakoulas G, Manning WJ, Cohn WE, Lisbon A "Corynebacterium jeikeium native valve endocarditis following femoral access for coronary angiography.." Clin. Infect. Dis.. 2001 Apr 1;32(7):E120-1. Pubmed PMID: 11264050
- Cohn WE, Winkler JA, Tuzun E, Hjelle A, Bassett K, Ahmad A, Frazier OH "Contrast pericardiography facilitates intrapericardial navigation under fluoroscopy.." Ann. Thorac. Surg.. 2010 Nov;90(5):1537-40. Pubmed PMID: 20971258
- Frazier OH, Cohn WE, Tuzun E, Winkler JA, Gregoric ID "Continuous-flow total artificial heart supports long-term survival of a calf.." Tex Heart Inst J. 2009;36(6):568-74. Pubmed PMID: 20069083
- Khalil HA, Kerr DT, Franchek MA, Metcalfe RW, Benkowski RJ, Cohn WE, Tuzun E, Radovancevic B, Frazier OH, Kadipasaoglu KA "Continuous flow total artificial heart: modeling and feedback control in a mock circulatory system.." ASAIO J..;54(3):249-55. Pubmed PMID: 18496274
- Cohn W, Thürmann P, Tenter U, Aebischer C, Schierle J, Schalch W "Comparative multiple dose plasma kinetics of lycopene administered in tomato juice, tomato soup or lycopene tablets.." Eur J Nutr. 2004 Oct;43(5):304-12. Pubmed PMID: 15309451
- Bruckner BA, Jacob LP, Gregoric ID, Loyalka P, Kar B, Cohn WE, La Francesca S, Radovancevic B, Frazier OH "Clinical experience with the TandemHeart percutaneous ventricular assist device as a bridge to cardiac transplantation.." Tex Heart Inst J. 2008;35(4):447-50. Pubmed PMID: 19156239
- Johnson RG, Cohn WE, Thurer RL, McCarthy JR, Sirois CA, Weintraub RM "Cutaneous closure after cardiac operations: a controlled, randomized, prospective comparison of intradermal versus staple closures.." Ann. Surg.. 1997 Nov;226(5):606-12. Pubmed PMID: 9389394
- MICHELSON AM, COHN WE "Cyclo-pseudouridine and the configuration of pseudouridine.." Biochemistry. 1962 May 25;1:490-5. Pubmed PMID: 14473444
- Uziel M, Cohn WE "Desalting of nucleotides by gel filtration.." Biochim. Biophys. Acta. 1965 Jul 15;103(3):539-41. Pubmed PMID: 5853501
- Daimon M, Gillinov AM, Liddicoat JR, Saracino G, Fukuda S, Koyama Y, Hayase M, Cohn WE, Ellis SG, Thomas JD, Shiota T "Dynamic change in mitral annular area and motion during percutaneous mitral annuloplasty for ischemic mitral regurgitation: preliminary animal study with real-time 3-dimensional echocardiography.." J Am Soc Echocardiogr. 2007 Apr;20(4):381-8. Pubmed PMID: 17400117
- BRUES AM, WESSON LG, COHN WE "Effect of temperature on potassium metabolism in chick embryo muscle.." Anat. Rec.. 1946 Mar;94:451. Pubmed PMID: 21020577
- Tuzun E, Cohn WE, Gilbert N, Winkler JA, Costas G, Conger JL, Frazier OH "Elective tracheotomy facilitates total artificial heart implantation in calves.." ASAIO J..;55(5):456-8. Pubmed PMID: 19672192
- VOLKIN E, COHN WE "Estimation of nucleic acids.." Methods Biochem Anal. 1954;1:287-305. Pubmed PMID: 13193533
- Cohn W "Evaluation of vitamin E potency.." Am. J. Clin. Nutr.. 1999 Jan;69(1):156-8. Pubmed PMID: 9925140
- Mazzitelli D, Nöbauer C, Rankin JS, Badiu CC, Krane M, Crooke PS, Cohn WE, Opitz A, Schreiber C, Lange R "Early results after implantation of a new geometric annuloplasty ring for aortic valve repair.." Ann. Thorac. Surg.. 2013 Jan;95(1):94-7. Pubmed PMID: 23063198
- Ruel MA, Sellke FW, Bianchi C, Khan TA, Faro R, Zhang JP, Cohn WE "Endogenous myocardial angiogenesis and revascularization using a gastric submucosal patch.." Ann. Thorac. Surg.. 2003 May;75(5):1443-9. Pubmed PMID: 12735560
- Anderson JC, Messina CR, Cohn W, Gottfried E, Ingber S, Bernstein G, Coman E, Polito J "Factors predictive of difficult colonoscopy.." Gastrointest. Endosc.. 2001 Nov;54(5):558-62. Pubmed PMID: 11677470
- Khalil HA, Metcalfe RW, Kleis SJ, Lee EL, Gilbert NL, Kerr DT, Frazier OH, Cohn WE "Flow visualization techniques in a mock ventricle supported by a nonpulsatile left ventricular assist device.." ASAIO J..;55(4):323-7. Pubmed PMID: 19512887
- Cope O, Cohn WE, Brenizer AG "GASTRIC SECRETION. II. ABSORPTION OF RADIOACTIVE SODIUM FROM POUCHES OF THE BODY AND ANTRUM OF THE STOMACH OF THE DOG.." J. Clin. Invest.. 1943 Jan;22(1):103-10. Pubmed PMID: 16694970
- Akay MH, Gregoric I, Cohn WE, Frazier OH "HeartMate-II Left Ventricular Assist Device Infections Resulting from Gastrointestinal-Tract Fistulas.." J Card Surg. 2012 Sep;27(5):643-5. Pubmed PMID: 22978845
- Cohn WE, Tuzun E, Simonak R, Baimbridge F "Hemostatic control of coronary arteries with poloxamer 407 reverse-thermal polymer during off-pump coronary artery bypass surgery in a pig model.." Innovations (Phila). 2007 Jan;2(1):36-9. Pubmed PMID: 22436876
- Bourque K, Dague C, Farrar D, Harms K, Tamez D, Cohn W, Tuzun E, Poirier V, Frazier OH "In vivo assessment of a rotary left ventricular assist device-induced artificial pulse in the proximal and distal aorta.." Artif Organs. 2006 Aug;30(8):638-42. Pubmed PMID: 16911321
- Tuzun E, Roberts K, Cohn WE, Sargin M, Gemmato CJ, Radovancevic B, Frazier OH "In vivo evaluation of the HeartWare centrifugal ventricular assist device.." Tex Heart Inst J. 2007;34(4):406-11. Pubmed PMID: 18172519
- Rankin JS, Conger JL, Tuzun E, Winkler JA, Harms KM, Beavan LA, Fossum T, Cohn WE "In vivo testing of an intra-annular aortic valve annuloplasty ring in a chronic calf model.." Eur J Cardiothorac Surg. 2012 Jul;42(1):149-54. Pubmed PMID: 22362620
- Hernandez F, Cohn WE, Baribeau YR, Tryzelaar JF, Charlesworth DC, Clough RA, Klemperer JD, Morton JR, Westbrook BM, Olmstead EM, O'Connor GT "In-hospital outcomes of off-pump versus on-pump coronary artery bypass procedures: a multicenter experience.." Ann. Thorac. Surg.. 2001 Nov;72(5):1528-33; discus. Pubmed PMID: 11722038
- Palanichamy N, Letsou GV, Cohn W, La Francesca S, Kar B, Gregoric ID "High cardiac output due to fistula after cardiac transplantation.." Congest Heart Fail.;13(4):237-9. Pubmed PMID: 17673877
- Shabari FR, George J, Cuchiara MP, Langsner RJ, Heuring JJ, Cohn WE, Hertzog BA, Delgado R "Improved Hemodynamics With a Novel Miniaturized Intra-aortic Axial Flow Pump in a Porcine Model of Acute Left Ventricular Dysfunction.." ASAIO J..;59(3):240-5. Pubmed PMID: 23644610
- Khalil HA, Kerr DT, Schusterman MA, Cohn WE, Frazier OH, Radovancevic B "Induced pulsation of a continuous-flow total artificial heart in a mock circulatory system.." J. Heart Lung Transplant.. 2010 May;29(5):568-73. Pubmed PMID: 20153967
- Frazier OH, Gregoric ID, Cohn WE "Initial experience with non-thoracic, extraperitoneal, off-pump insertion of the Jarvik 2000 Heart in patients with previous median sternotomy.." J. Heart Lung Transplant.. 2006 May;25(5):499-503. Pubmed PMID: 16678026
- Cohn WE, Weintraub RM, Sellke FW "Innovative minimally invasive surgical approaches to coronary revascularization in the high risk patient.." Heart Surg Forum. 2000;3(3):185-8. Pubmed PMID: 11074970
- Cohn WE, Ruel M, Zhang JP, Sellke FW, Johnson RG "Internal thoracic artery flow competition: studies in a canine H-graft model.." Eur J Cardiothorac Surg. 2003 Jan;23(1):56-9. Pubmed PMID: 12493505
- Anderson WF, Bosch L, Cohn WE, Lodish H, Merrick WC, Weissbach H, Wittmann HG, Wool IG "International symposium on protein synthesis. Summary of Fogarty Center-NIH Workshop held in Bethesda, Maryland on 18-20 October, 1976.." FEBS Lett.. 1977 Apr 1;76(1):41284. Pubmed PMID: 323054
- Loebe M, Bruckner B, Reardon MJ, van Doorn E, Estep J, Gregoric I, Masud F, Cohn W, Motomura T, Torre-Amione G, Frazier OH "Initial clinical experience of total cardiac replacement with dual Heartmate-II axial flow pumps for severe biventricular heart failure.." Methodist DeBakey Cardiovasc J.;7(1):40-4. Pubmed PMID: 21490553
- Ruel M, Streeter RB, de la Torre R, Liddicoat JR, Cohn WE "Intracardiac ultrasonic suture welding for knotless mitral valve replacement.." Eur J Cardiothorac Surg. 2002 Feb;21(2):245-8. Pubmed PMID: 11825730
- Cohn WE, Morris CD, Reverdin S, Frazier OH, Gregoric ID "Intraoperative TandemHeart implantation as an adjunct to high-risk valve surgery.." Tex Heart Inst J. 2007;34(4):457-8. Pubmed PMID: 18172530
- TOMPKINS ER, KHYM JX, COHN WE "Ion-exchange as a separations method; the separation of fission-produced radioisotopes, including individual rare earths, by complexing elution from amberlite resin.." J. Am. Chem. Soc.. 1947 Nov;69(11):2769-77. Pubmed PMID: 20270829
- COHN WE, KOHN RW "Ion-exchange separation of the alkali metals.." J. Am. Chem. Soc.. 1948 May;70(5):1986. Pubmed PMID: 18861852
- Cohn WE, de La Torre R, Liddicoat JR "Is the future of cardiac surgery in the hands of the interventional cardiologist?." Heart Surg Forum. 2001;4(4):297-300. Pubmed PMID: 11827854
- Pal BC, Uziel M, Doherty DG, Cohn WE "Isolation and characterization of pyrimidine sulfenic acid via scission of the sulfur-sulfur bond in the methyl analog of bis(4-thiouridine) disulfide.." J. Am. Chem. Soc.. 1969 Jun 18;91(13):3634-8. Pubmed PMID: 5784191
- Miesfeldt S, Cohn W, Ropka M, Jones S "Knowledge about breast cancer risk factors and hereditary breast cancer among early-onset breast cancer survivors.." Fam. Cancer. 2001;1(41337):135-41. Pubmed PMID: 14574169
- Maslow A, Lowenstein E, Steriti J, Leckie R, Cohn W, Haering M "Left ventricular thrombi: intraoperative detection by transesophageal echocardiography and recognition of a source of post CABG embolic stroke: a case series.." Anesthesiology. 1998 Nov;89(5):1257-62. Pubmed PMID: 9822018
- Fukuda S, Gillinov AM, Liddicoat JR, Saracino G, Hayase M, Cohn WE, Schneider CW, Shiota T "Maintenance of geometric alterations associated with percutaneous mitral valve repair: real-time three-dimensional echocardiographic assessment in an ovine model.." J. Heart Valve Dis.. 2008 May;17(3):276-82. Pubmed PMID: 18592924
- Miesfeldt S, Jones SM, Cohn W, Lippert M, Haden K, Turner BL, Martin-Fries T, Clark SM "Men's attitudes regarding genetic testing for hereditary prostate cancer risk.." Urology. 2000 Jan;55(1):46-50. Pubmed PMID: 10654893
- Cohn WE, Brues AM "METABOLISM OF TISSUE CULTURES : III. A METHOD FOR MEASURING THE PERMEABILITY OF TISSUE CELLS TO SOLUTES.." J. Gen. Physiol.. 1945 May 20;28(5):449-61. Pubmed PMID: 19873432
- Pawlowski J, Haering JM, Comunale ME, Mashikian J, Reynolds D, Johnson R, Cohn W "Minimally invasive anesthesia should accompany minimally invasive surgery.." J. Cardiothorac. Vasc. Anesth.. 1997 Jun;11(4):536-7. Pubmed PMID: 9188010
- Maslow AD, Park KW, Pawlowski J, Haering JM, Cohn WE "Minimally invasive direct coronary artery bypass grafting: changes in anesthetic management and surgical procedure.." J. Cardiothorac. Vasc. Anesth.. 1999 Aug;13(4):417-23. Pubmed PMID: 10468254
- Suen HC, Johnson RG, Weintraub RM, Maslow A, Comunale ME, Cohn WE "Minimally invasive direct coronary artery bypass: our experience with 32 patients.." Int. J. Cardiol.. 1997 Dec 1;62:S95-100. Pubmed PMID: 9464591
- COHN WE, VOLKIN E "Mononucleotides from ribonucleic acid by phosphodiesterase action; the isolation of pyrimidine diphosphates.." Arch Biochem. 1952 Feb;35(2):465-7. Pubmed PMID: 14924670
- Bisswanger H, Kirschner K, Cohn W, Hager V, Hansson E "N-(5-Phosphoribosyl)anthranilate isomerase-indoleglycerol-phosphate synthase. 1. A substrate analogue binds to two different binding sites on the bifunctional enzyme from Escherichia coli.." Biochemistry. 1979 Dec 25;18(26):5946-53. Pubmed PMID: 391279
- Cohn W, Kirschner K, Paul C "N-(5-Phosphoribosyl)anthranilate isomerase-indoleglycerol-phosphate synthase. 2. Fast-reaction studies show that a fluorescent substrate analogue binds independently to two different sites.." Biochemistry. 1979 Dec 25;18(26):5953-9. Pubmed PMID: 391280
- Friedman M, Wang SY, Sellke FW, Cohn WE, Weintraub RM, Johnson RG "Neutrophil adhesion blockade with NPC 15669 decreases pulmonary injury after total cardiopulmonary bypass.." J. Thorac. Cardiovasc. Surg.. 1996 Feb;111(2):460-8. Pubmed PMID: 8583821
- Cohn WE "New surgical approaches for coronary disease: what's coming?." Tex Heart Inst J. 2005;32(3):354-7. Pubmed PMID: 16392217
- Cohn WE "New tools and techniques to facilitate off-pump left ventricular assist device implantation.." Tex Heart Inst J. 2010;37(5):559-61. Pubmed PMID: 20978568
- Cohn WE "Nomenclature and symbolism of alpha-amino acids.." Meth. Enzymol.. 1984;106:41350. Pubmed PMID: 6493060
- Cohn WE, Frazier OH "Off-pump insertion of an extracorporeal LVAD through a left upper-quadrant incision.." Tex Heart Inst J. 2006;33(1):48-50. Pubmed PMID: 16572869
- COHN WE, VOLKIN E "On the structure of ribonucleic acids. I. Degradation with snake venom diesterase and the isolation of pyrimidine diphosphates.." J. Biol. Chem.. 1953 Jul;203(1):319-32. Pubmed PMID: 13069515
- VOLKIN E, COHN WE "On the structure of ribonucleic acids. II. The products of ribonuclease action.." J. Biol. Chem.. 1953 Dec;205(2):767-82. Pubmed PMID: 13129256
- Frazier OH, Khalil HA, Benkowski RJ, Cohn WE "Optimization of axial-pump pressure sensitivity for a continuous-flow total artificial heart.." J. Heart Lung Transplant.. 2010 Jun;29(6):687-91. Pubmed PMID: 20133164
- Smith RD, Radovancevic B, Gregoric ID, Cohn WE, Frazier OH "Orthotopic retransplantation in heterotopic transplant recipients: 3 case reports.." J. Heart Lung Transplant.. 2006 Feb;25(2):245-7. Pubmed PMID: 16446229
- Daimon M, Shiota T, Gillinov AM, Hayase M, Ruel M, Cohn WE, Blacker SJ, Liddicoat JR "Percutaneous mitral valve repair for chronic ischemic mitral regurgitation: a real-time three-dimensional echocardiographic study in an ovine model.." Circulation. 2005 May 3;111(17):2183-9. Pubmed PMID: 15851597
- Liddicoat JR, Mac Neill BD, Gillinov AM, Cohn WE, Chin CH, Prado AD, Pandian NG, Oesterle SN "Percutaneous mitral valve repair: a feasibility study in an ovine model of acute ischemic mitral regurgitation.." Catheter Cardiovasc Interv. 2003 Nov;60(3):410-6. Pubmed PMID: 14571496
- Cohn WE "Percutaneous valve interventions: where we are and where we are headed.." Am Heart Hosp J. 2006;4(3):186-91. Pubmed PMID: 16894254
- Amir O, Radovancevic B, Delgado RM, Kar B, Radovancevic R, Henderson M, Cohn WE, Smart FW "Peripheral vascular reactivity in patients with pulsatile vs axial flow left ventricular assist device support.." J. Heart Lung Transplant.. 2006 Apr;25(4):391-4. Pubmed PMID: 16563966
- COHN WE "Pile production of radioactive isotopes.." U S Nav Med Bull.;48:42-51. Pubmed PMID: 18859228
- Morris CD, Gregoric ID, Cooley DA, Cohn WE, Loyalka P, Frazier OH "Placement of a continuous-flow ventricular assist device in the failing ventricle of an adult patient with complex cyanotic congenital heart disease.." Heart Surg Forum. 2008;11(3):E143-4. Pubmed PMID: 18583283
- Cohn W, Goss-Sampson MA, Grun H, Muller DP "Plasma clearance and net uptake of alpha-tocopherol and low-density lipoprotein by tissues in WHHL and control rabbits.." Biochem. J.. 1992 Oct 1;287:247-54. Pubmed PMID: 1329730
- Thürmann PA, Schalch W, Aebischer JC, Tenter U, Cohn W "Plasma kinetics of lutein, zeaxanthin, and 3-dehydro-lutein after multiple oral doses of a lutein supplement.." Am. J. Clin. Nutr.. 2005 Jul;82(1):88-97. Pubmed PMID: 16002805
- Hartmann D, Thürmann PA, Spitzer V, Schalch W, Manner B, Cohn W "Plasma kinetics of zeaxanthin and 3'-dehydro-lutein after multiple oral doses of synthetic zeaxanthin.." Am. J. Clin. Nutr.. 2004 Mar;79(3):410-7. Pubmed PMID: 14985215
- POCHON F, MICHELSON AM, GRUNBERG-MANAGO M, COHN WE, DONDON L "POLYNUCLEOTIDE ANALOGUES. III. POLYPSEUDOURIDYLIC ACID: SYNTHESIS AND SOME PHYSICOCHEMICAL AND BIOCHEMICAL PROPERTIES.." Biochim. Biophys. Acta. 1964 Mar 23;80:441-7. Pubmed PMID: 14153846
- Maslow AD, Regan MM, Heindle S, Panzica P, Cohn WE, Johnson RG "Postoperative atrial tachyarrhythmias in patients undergoing coronary artery bypass graft surgery without cardiopulmonary bypass: a role for intraoperative magnesium supplementation.." J. Cardiothorac. Vasc. Anesth.. 2000 Oct;14(5):524-30. Pubmed PMID: 11052432
- Johnson RG, Sirois C, Thurer RL, Sellke FW, Cohn WE, Kuntz RE, Weintraub RM "Predictors of CABG within one year of successful PTCA: a retrospective, case-control study.." Ann. Thorac. Surg.. 1997 Jul;64(1):3-7; discussion. Pubmed PMID: 9236327
- Khalil HA, Cohn WE, Metcalfe RW, Frazier OH "Preload sensitivity of the Jarvik 2000 and HeartMate II left ventricular assist devices.." ASAIO J..;54(3):245-8. Pubmed PMID: 18496273
- COHN WE "Pseudouridine, a carbon-carbon linked ribonucleoside in ribonucleic acids: isolation, structure, and chemical characteristics.." J. Biol. Chem.. 1960 May;235:1488-98. Pubmed PMID: 13811056
- Uziel M, Koh CK, Cohn WE "Rapid ion-exchange chromatographic microanalysis of ultraviolet-absorbing materials and its application to nucleosides.." Anal. Biochem.. 1968 Oct 24;25(1):77-98. Pubmed PMID: 5704775
- Hariawala MD, Cohn WE, Tofukuji M, Allman GW, Suen HC, Johnson RG "Re: The latissimus dorsi perforator-based fasciocutaneous flap.." Ann Plast Surg. 1997 May;38(5):550. Pubmed PMID: 9160145
- Akay MH, Danch MA, Cohn WE, Frazier OH "Reconstruction of the fibrous trigone.." Tex Heart Inst J. 2009;36(5):475-6. Pubmed PMID: 19876433
- Amir O, Delgado RM, Kar B, Gregoric ID, Radovancevic B, Smart F, Cohn W "Recovery from multi-organ failure in a patient with a continuous-flow left ventricular assist device.." J. Heart Lung Transplant.. 2005 Aug;24(8):1128-9. Pubmed PMID: 16102456
- Amir O, Delgado RM, Kar B, Gregoric ID, Radovancevic B, Smart F, Cohn W "Recovery from multi-organ failure in a patient with a continuous-flow left ventricular assist device.." J. Heart Lung Transplant.. 2006 Jan;25(1):148. Pubmed PMID: 16399549
- Cohn W, Crawford IP "Regulation of enzyme synthesis in the tryptophan pathway of Acinetobacter calcoaceticus.." J. Bacteriol.. 1976 Jul;127(1):367-79. Pubmed PMID: 931950
- Cohn WE, Gregoric ID, Frazier OH "Reinforcement of left ventricular assist device outflow grafts to prevent kinking.." Ann. Thorac. Surg.. 2007 Jul;84(1):301-2. Pubmed PMID: 17588447
- Cohn WE, Fikfak V, Gregoric ID, Frazier OH "Retention of left ventricular assist device outflow grafts after transplantation.." J. Heart Lung Transplant.. 2008 Aug;27(8):865-8. Pubmed PMID: 18656799
- de la Cruz KI, Tsai PI, Cohn WE, Cooley DA "Revascularization treatment recommendations based on atherosclerotic disease distribution: coronary artery bypass grafting versus stenting.." Curr Atheroscler Rep. 2008 Oct;10(5):434-7. Pubmed PMID: 18706285
- Frazier OH, Tuzun E, Narin C, Cohn WE "Right ventricle-sparing left ventricular resection and replacement with a continuous-flow rotary blood pump: an in vivo experiment.." Tex Heart Inst J. 2010;37(3):276-9. Pubmed PMID: 20548801
- Boodhwani M, Cohn WE, Feng J, Ramlawi B, Mieno S, Schwarz A, Sellke FW "Safety and efficacy of a novel gel for vascular occlusion in off-pump surgery.." Ann. Thorac. Surg.. 2005 Dec;80(6):2333-7. Pubmed PMID: 16305901
- Ullmann U, Metzner J, Frank T, Cohn W, Riegger C "Safety, tolerability, and pharmacokinetics of single ascending doses of synthetic genistein (Bonistein) in healthy volunteers.." Adv Ther.;22(1):65-78. Pubmed PMID: 15943224
- COHN WE "Some results of the applications of ion-exchange chromatography to nucleic acid chemistry.." J Cell Physiol Suppl. 1951 Jul;38:21-40. Pubmed PMID: 14861275
- Cohn W, Gregoric ID, Frazier OH "Staged reoperation: a novel strategy for high-risk patients.." Ann. Thorac. Surg.. 2007 Apr;83(4):1558-9. Pubmed PMID: 17383391
- Tuzun E, Parnis S, Rios J, Winkler JA, Cohn WE "Stent treatment of inferior vena cava compression in an ovine with a total artificial heart.." Artif Organs. 2011 Jul;35(7):E161-3. Pubmed PMID: 21615430
- Greenberg DM, Joseph M, Cohn WE, Tufts EV "STUDIES IN THE POTASSIUM METABOLISM OF THE ANIMAL BODY BY MEANS OF ITS ARTIFICIAL RADIOACTIVE ISOTOPE.." Science. 1938 May 13;87(2263):438. Pubmed PMID: 17781038
- La Francesca S, Gregoric ID, Cohn WE, Frazier OH "Successful resection of a primary left ventricular schwannoma.." Ann. Thorac. Surg.. 2007 May;83(5):1881-2. Pubmed PMID: 17462424
- Cohn WE, Demirozu ZT, Frazier OH "Surgical closure of left ventricular outflow tract after left ventricular assist device implantation in patients with aortic valve pathology.." J. Heart Lung Transplant.. 2011 Jan;30(1):59-63. Pubmed PMID: 20884246
- Cohn WE "Surgical coronary revascularization remains relevant in the era of stents.." Curr. Opin. Cardiol.. 2004 Nov;19(6):589-92. Pubmed PMID: 15502503
- Cohn WE, Sellke FW, Sirois C, Lisbon A, Johnson RG "Surgical ICU recidivism after cardiac operations.." Chest. 1999 Sep;116(3):688-92. Pubmed PMID: 10492272
- Bouchot O, Aubin MC, Carrier M, Cohn WE, Perrault LP "Temporary coronary artery occlusion during off-pump coronary artery bypass grafting with the new poloxamer P407 does not cause endothelial dysfunction in epicardial coronary arteries.." J. Thorac. Cardiovasc. Surg.. 2006 Nov;132(5):1144-9. Pubmed PMID: 17059936
- Aubin MC, Bouchot O, Carrier M, Cohn WE, Perrault LP "Temporary internal thoracic artery occlusion during off-pump coronary artery bypass grafting with the new poloxamer P407 does not cause endothelial dysfunction.." J. Thorac. Cardiovasc. Surg.. 2006 Sep;132(3):685-6. Pubmed PMID: 16935129
- Shalli S, Boyle EM, Saeed D, Fukamachi K, Cohn WE, Gillinov AM "The active tube clearance system: a novel bedside chest-tube clearance device.." Innovations (Phila). 2010 Jan;5(1):42-7. Pubmed PMID: 22437275
- Greenberg DM, Cohn WE "THE BOUND" WATER OF BIOLOGICAL COLLOIDS: A REPLY."." J. Gen. Physiol.. 1934 Sep 20;18(1):93-6. Pubmed PMID: 19872828
- WESSON LG, COHN WE, BRUES AM "The effect of temperature on potassium equilibria in chick embryo muscle.." J. Gen. Physiol.. 1949 Mar 20;32(4):511-23. Pubmed PMID: 18114563
- SHEPPARD CW, COHN WE, MATHIAS PJ "The estimation of choline esters by ion exchange.." Arch. Biochem. Biophys.. 1953 Dec;47(2):475-7. Pubmed PMID: 13114918
- Kusama K, Prescott DM, Fröholm LO, Cohn WE "The formation and metabolic interchanges of pseudouridine in Tetrahymena pyriformis.." J. Biol. Chem.. 1966 Sep 10;241(17):4086-91. Pubmed PMID: 5920814
- Cohn WE, Suen HC, Weintraub RM, Johnson RG "The H" graft: an alternative approach for performing minimally invasive direct coronary artery bypass."." J. Thorac. Cardiovasc. Surg.. 1998 Jan;115(1):148-51. Pubmed PMID: 9451058
- KHYM JX, COHN WE "The ion-exchange separation of the 5'-ribonucleotides and deoxyribonucleotides.." Biochim. Biophys. Acta. 1954 Sep;15(1):139. Pubmed PMID: 13198949
- COHN WE "The nature and production of artificial radioactivity.." Adv Biol Med Phys. 1948;1:117-49. Pubmed PMID: 18114518
- COHN WE, VOLKIN E "The nucleic acids.." Annu. Rev. Biochem.. 1957;26:491-522. Pubmed PMID: 13488401
- Brues AM, Tracy MM, Cohn WE "THE RELATION BETWEEN NUCLEIC ACID AND GROWTH.." Science. 1942 May 29;95(2474):558-60. Pubmed PMID: 17790873
- Cohn W, Kuhn H "The role of the low density lipoprotein receptor for alpha-tocopherol delivery to tissues.." Ann. N. Y. Acad. Sci.. 1989;570:61-71. Pubmed PMID: 2629610
- COHN WE "The separation of biochemically important substances by ion exchange chromatography.." Ann. N. Y. Acad. Sci.. 1953 Nov 11;57(3):204-24. Pubmed PMID: 13139317
- Cohn WE "The Separation of Purine and Pyrimidine Bases and of Nucleotides by Ion Exchange.." Science. 1949 Apr 15;109(2833):377-8. Pubmed PMID: 17749594
- BRUES AM, COHN WE "The toxic factors in experimental traumatic shock; studies on electrolyte and water balance in shock.." J. Clin. Invest.. 1945 Nov;24:835-8. Pubmed PMID: 21010036
- Brues AM, Cohn WE, Kety SS, Nathanson IT, Nutt AL, Tibbetts DM, Zamecnik PC, Aub JC "THE TOXIC FACTORS IN EXPERIMENTAL TRAUMATIC SHOCK. II. STUDIES ON ELECTROLYTE AND WATER BALANCE IN SHOCK.." J. Clin. Invest.. 1945 Nov;24(6):835-8. Pubmed PMID: 16695278
- Akay MH, Gregoric ID, Radovancevic R, Cohn WE, Frazier OH "Timely Use of a CentriMag Heart Assist Device Improves Survival in Postcardiotomy Cardiogenic Shock.." J Card Surg. 2011 Sep;26(5):548-52. Pubmed PMID: 21951040
- Cohn W, Gross P, Grun H, Loechleiter F, Muller DP, Zulauf M "Tocopherol transport and absorption.." Proc Nutr Soc. 1992 Aug;51(2):179-88. Pubmed PMID: 1438326
- Frazier OH, Tuzun E, Cohn WE, Conger JL, Kadipasaoglu KA "Total heart replacement using dual intracorporeal continuous-flow pumps in a chronic bovine model: a feasibility study.." ASAIO J..;52(2):145-9. Pubmed PMID: 16557099
- COHN WE "Toxicity of inhaled or ingested radioactive products.." Nucleonics. 1948 Jul;3(1):21-6. Pubmed PMID: 18873344
- Jafar M, Gregoric ID, Radovancevic R, Cohn WE, McGuire N, Frazier OH "Urgent exchange of a HeartMate II left ventricular assist device after percutaneous lead fracture.." ASAIO J..;55(5):523-4. Pubmed PMID: 19730010
- Mommerot A, Aubin MC, Carrier M, Cohn WE, Perrault LP "Use of the Purified Poloxamer 407 for Temporary Coronary Occlusion in Off-Pump CABG Does Not Cause Myocardial Injury.." Innovations (Phila). 2007 Jul;2(4):201-4. Pubmed PMID: 22437061
- Hoenig SJ, Hodin RA, Novak G, Cohn WE "Videoscopic harvest of the inferior epigastric artery.." Ann. Thorac. Surg.. 1999 Feb;67(2):565-6. Pubmed PMID: 10197701
- Schalch W, Cohn W, Barker FM, Köpcke W, Mellerio J, Bird AC, Robson AG, Fitzke FF, van Kuijk FJ "Xanthophyll accumulation in the human retina during supplementation with lutein or zeaxanthin - the LUXEA (LUtein Xanthophyll Eye Accumulation) study.." Arch. Biochem. Biophys.. 2007 Feb 15;458(2):128-35. Pubmed PMID: 17084803
Memberships
- American College of Surgeons
- Fellow
- International Society of Minimally Invasive Cardiac Surgery
- Fellow
- American College of Chest Physicians
- Fellow
- American Heart Association / American Stroke Association
- Fellow
- 21st Century Cardiac Surgical Society
- Society of Thoracic Surgeons
- Michael E. DeBakey Surgical Society
- Harris County Medical Society
- Texas Medical Society
- Denton A. Cooley Cardiovascular Surgical Society
- International Society for Heart and Lung Transplantation
- Southern Thoracic Surgical Association
- American Institute for Medical and Biological Engineering
- Fellow
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