Email

yanmingl@bcm.edu

Positions

Instructor

Surgery/Cardio/Thoracic Surg.
Baylor College of Medicine
Houston, TX US

Addresses

St Lukes-Denton Cooley (Lab)

Room: SLDC-C-1095
Houston, TX 77030
United States

Education

Postdoctoral Fellowship at Baylor College of Medicine

09/2023 - Houston, Texas United States

PhD from University of Chinese Academy of Sciences

07/2015 - Beijing, China

BS from Shandong University

07/2010 - Weihai, Shandong China

Professional Statement

Investigating the cellular, molecular, and epigenetic regulation of cardiovascular disease through multi-omics and functional studies.

Websites

Selected Publications

• Yanming Li, Pingping Ren, Ashley Dawson, Hernan G. Vasquez, Waleed Ageedi, Chen Zhang, Wei Luo, Rui Chen, Yumei Li, Sangbae Kim, Hong S. Lu, Lisa A. Cassis, Joseph S. Coselli, Alan Daugherty, Ying H. Shen, Scott A. LeMaire "Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue." Circulation. 2020;142(14):1374–1388. Pubmed PMID: 33017217
• Yanming Li, Scott A LeMaire, Ying H Shen "Molecular and cellular dynamics of aortic aneurysms revealed by single-cell transcriptomics." Arteriosclerosis, Thrombosis, and Vascular Biology. 2021;41(11):2671-2680. Pubmed PMID: 34615376
• Chen Zhang*, Yanming Li*, Abhijit Chakraborty, Yang Li, Kimberly R Rebello, Pingping Ren, Wei Luo, Lin Zhang, Hong S Lu, Lisa A Cassis, Joseph S Coselli, Alan Daugherty, Scott A LeMaire, Ying H Shen "Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in Mice." Arteriosclerosis, Thrombosis, and Vascular Biology. 2023;43(2):234-252. Pubmed PMID: 36579645
• Abhijit Chakraborty*, Yanming Li*, Chen Zhang*, Yang Li, Kimberly R Rebello, Shengyu Li, Samantha Xu, Hernan G Vasquez, Lin Zhang, Wei Luo, Guangyu Wang, Kaifu Chen, Joseph S Coselli, Scott A LeMaire, Ying H Shen "Epigenetic Induction of Smooth Muscle Cell Phenotypic Alterations in Aortic Aneurysms and Dissections." Circulation. 2023;123(063332) Pubmed PMID: 37555319

Funding

Aortic Disease-Associated SNPs Lead to Epigenetic Regulation Alterations That Increase Susceptibility to Aortic Aneurysm and Dissection - #R21HL181658

$150,000.00 ( 08/15/2025 - 07/31/2027 )

Grant funding from NIH

Surgery Genome Seed Award

$25,000.00 ( 10/01/2024 - 09/30/2025 )

Grant funding from Baylor College of Medicine

Somatic Mutations Lead To Epigenetic Regulation Alterations That Drive Aortic Aneurysm and Dissection

Research Seed Grant

$25,000.00 ( 07/01/2024 - 06/30/2025 )

Michael E. DeBakey Department of Surgery, BCM

Epigenetic Regulation of Adaptive Genes Mediated by Transcription Factors in VSMCs during Aortic Disease Progression

Victor A. McKusick Fellowship Grant

$100,000.00 ( 01/01/2021 - 12/31/2022 )

THE MARFAN FOUNDATION

ScRNA-seq Reveals Crosstalk Between SMC-Like Cells and Macrophages in Aortic Tissues from Marfan Syndrome Patients