Wooton-Kee CR, Robertson M, Zhou Y, Dong B, Sun Z, Kim KH, Liu H, Xu Y, Putluri N, Saha P, Coarfa C, Moore DD, Nuotio-Antar AM. Metabolic dysregulation in the Atp7b-/- Wilson's disease mouse model. Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):2076-2083. doi: 10.1073/pnas.1914267117. Epub 2020 Jan 10. PubMed PMID: 31924743; PubMed Central PMCID: PMC6994990.
Kim KH, Choi JM, Li F, Dong B, Wooton-Kee CR, Arizpe A, Anakk S, Jung SY, Hartig SM, Moore DD. Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis. Hepatol Commun. 2019 Jan;3(1):147-159. doi: 10.1002/hep4.1274. eCollection 2019 Jan. PubMed PMID: 30620001; PubMed Central PMCID: PMC6312660.
Pankowicz FP, Barzi M, Kim KH, Legras X, Martins CS, Wooton-Kee CR, Lagor WR, Marini JC, Elsea SH, Bissig-Choisat B, Moore DD, Bissig KD. Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing. Gastroenterology. 2018 Dec;155(6):1967-1970.e6. doi: 10.1053/j.gastro.2018.08.037. Epub 2018 Aug 28. PubMed PMID: 30170115; PubMed Central PMCID: PMC6420307.
Kim KH, Choi JM, Li F, Arizpe A, Wooton-Kee CR, Anakk S, Jung SY, Finegold MJ, Moore DD. Xenobiotic Nuclear Receptor Signaling Determines Molecular Pathogenesis of Progressive Familial Intrahepatic Cholestasis. Endocrinology. 2018 Jun 1;159(6):2435-2446. doi: 10.1210/en.2018-00110. PubMed PMID: 29718219; PubMed Central PMCID: PMC7263843.
Muchenditsi A, Yang H, Hamilton JP, Koganti L, Housseau F, Aronov L, Fan H, Pierson H, Bhattacharjee A, Murphy R, Sears C, Potter J, Wooton-Kee CR, Lutsenko S. Targeted inactivation of copper transporter Atp7b in hepatocytes causes liver steatosis and obesity in mice. Am J Physiol Gastrointest Liver Physiol. 2017 Jul 1;313(1):G39-G49. doi: 10.1152/ajpgi.00312.2016. Epub 2017 Apr 20. PubMed PMID: 28428350; PubMed Central PMCID: PMC5538836.
Wagner M, Choi S, Panzitt K, Mamrosh JL, Lee JM, Zaufel A, Xiao R, Wooton-Kee R, Ståhlman M, Newgard CB, Borén J, Moore DD. Liver receptor homolog-1 is a critical determinant of methyl-pool metabolism. Hepatology. 2016 Jan;63(1):95-106. doi: 10.1002/hep.28124. Epub 2015 Oct 10. PubMed PMID: 26267291; PubMed Central PMCID: PMC5662191.
Wooton-Kee CR, Jain AK, Wagner M, Grusak MA, Finegold MJ, Lutsenko S, Moore DD. Elevated copper impairs hepatic nuclear receptor function in Wilson's disease. J Clin Invest. 2015 Sep;125(9):3449-60. doi: 10.1172/JCI78991. Epub 2015 Aug 4. PubMed PMID: 26241054; PubMed Central PMCID: PMC4588285.
Athippozhy A, Huang L, Wooton-Kee CR, Zhao T, Jungsuwadee P, Stromberg AJ, Vore M. Differential gene expression in liver and small intestine from lactating rats compared to age-matched virgin controls detects increased mRNA of cholesterol biosynthetic genes. BMC Genomics. 2011 Feb 3;12:95. doi: 10.1186/1471-2164-12-95. PubMed PMID: 21291544; PubMed Central PMCID: PMC3045338.
Coy DJ, Wooton-Kee CR, Yan B, Sabeva N, Su K, Graf G, Vore M. ABCG5/ABCG8-independent biliary cholesterol excretion in lactating rats. Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G228-35. doi: 10.1152/ajpgi.00502.2009. Epub 2010 Apr 22. PubMed PMID: 20413720; PubMed Central PMCID: PMC2904104.
Wooton-Kee CR, Coy DJ, Athippozhy AT, Zhao T, Jones BR, Vore M. Mechanisms for increased expression of cholesterol 7alpha-hydroxylase (Cyp7a1) in lactating rats. Hepatology. 2010 Jan;51(1):277-85. doi: 10.1002/hep.23289. PubMed PMID: 19957370; PubMed Central PMCID: PMC2799537.
Wooton-Kee CR, Cohen DE, Vore M. Increased cholesterol 7alpha-hydroxylase expression and size of the bile acid pool in the lactating rat. Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G1009-16. doi: 10.1152/ajpgi.00017.2008. Epub 2008 Feb 21. PubMed PMID: 18292185; PubMed Central PMCID: PMC2408447.
Wood M, Ananthanarayanan M, Jones B, Wooton-Kee R, Hoffman T, Suchy FJ, Vore M. Hormonal regulation of hepatic organic anion transporting polypeptides. Mol Pharmacol. 2005 Jul;68(1):218-25. doi: 10.1124/mol.104.010371. Epub 2005 Apr 19. PubMed PMID: 15840840; NIHMSID:NIHMS9989.
Wooton-Kee CR, Boyanovsky BB, Nasser MS, de Villiers WJ, Webb NR. Group V sPLA2 hydrolysis of low-density lipoprotein results in spontaneous particle aggregation and promotes macrophage foam cell formation. Arterioscler Thromb Vasc Biol. 2004 Apr;24(4):762-7. doi: 10.1161/01.ATV.0000122363.02961.c1. Epub 2004 Feb 12. PubMed PMID: 14962950.
Tabb AL, Utsugi T, Wooten-Kee CR, Sasaki T, Edling SA, Gump W, Kikuchi Y, Ellis SR. Genes encoding ribosomal proteins Rps0A/B of Saccharomyces cerevisiae interact with TOM1 mutants defective in ribosome synthesis. Genetics. 2001 Mar;157(3):1107-16. doi: 10.1093/genetics/157.3.1107. PubMed PMID: 11238398; PubMed Central PMCID: PMC1461576.
Wooton-Kee CR, Clark BJ. Steroidogenic factor-1 influences protein-deoxyribonucleic acid interactions within the cyclic adenosine 3,5-monophosphate-responsive regions of the murine steroidogenic acute regulatory protein gene. Endocrinology. 2000 Apr;141(4):1345-55. doi: 10.1210/endo.141.4.7412. PubMed PMID: 10746638.
