The Neuroendocrine Core is a specialized service offered through the H-NORC that will allow users access to cutting-edge resources, facilities, and consultations. Technologies and approaches to advance the field of neuroscience have expanded rapidly facilitating breakthroughs in our understanding of the contributions of the nervous system to the metabolic and endocrine functions that regulate obesity and nutrition-related diseases. The Neuroendocrine Core will permit Center members to leverage these findings and technological breakthroughs in support of their basic and translational studies.
Services
The objective of Neuroendocrine Core is to provide unique resources and expert advice to enhance research with innovative technologies at the intersection of neuroscience, endocrinology, obesity, and nutrition through the following services:
- Virus tools – deliver DNA recombinases, fluorescent reporters, tracers, biosensors, optogenetic/chemogenetic tool proteins in specific regions or specific cell types in rodent brains
- Stereotaxic injections – inject viruses or chemicals into specific regions of rodent brains
- Optogenetic/chemogenetic manipulations—selectively activate or inhibit a neural population or a neurocircuitry in rodent brains
- TSE PhenoMaster – indirect calorimetry and metabolic phenotyping
- E-mitter – measure body temperature and activity in home cages
- BioDAQ – measure food/water intake and food/drink preference
- Home-cage scan – 24/7 infrared monitoring of behavior
- Running-wheel – measure locomotor activity
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