Research

TMC Digestive Disease Center Past Pilot Awardees

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2024 Pilot Awardees

  • Charles Cho, M.D, Ph.D., Baylor College of Medicine - “Ribosomes in pancreatic metaplasia and tumorigenesis”
  • Xia Gao, Ph.D., Baylor College of Medicine - “Microbiome and phenylalanine metabolism in NAFLD”
  • Firas Midani, Ph.D., Baylor College of Medicine - “Microbial stimulation of serotonin in infants”
  • Jimin Min, Ph.D., MD Anderson Cancer Center - “Spatial omics of the normal pancreas across various ages”
  • Kavish Patidar, M.D., Baylor College of Medicine, Community-Acquired Acute Kidney Injury in Cirrhosis”
  • Jared Sninsky, M.D., Baylor College of Medicine - "SPEP Biomarker Model for Disease Activity in UC"
    Xiaoqin Wu, Ph.D., The University of Texas Health Science Center - "Role of adipose MLKL through EVs in NAFLD"

2023 Pilot Awardees

  • Lily Cheng, M.D., Baylor College of Medicine - “The effect of biomechanical forces on bowel function”
  • Thomas A. Cooper, M.D., Baylor College of Medicine - “Modeling myotonic dystrophy in visceral smooth muscle”
  • Ramon Jin, M.D. Ph.D., Baylor College of Medicine - “The role of SOX2 in Barrett's Esophagus Development”
  • Krupa Mysore, M.D., Baylor College of Medicine - “Mechanisms of impaired T cell function in cholestasis”
  • Theresa Nguyen-Wenker M.D., Baylor College of Medicine - "Barrett's Esophagus Screening Electronic Trigger Tool"
  • Yang Yang, Ph.D. The University of Texas Health Science Center - "Role of eosinophils-specific COX2 in IBD"

2022 Pilot Awardees

  • Sumimasa Arimura, Ph.D., Baylor College of Medicine - “Small intestinal engraftment in mice”
  • Heather Danhof, Ph.D., Baylor College of Medicine - “Gut hormones regulate localized inflammatory responses”
  • Yu An, Ph.D., The University of Texas Health Science Center - “Orm mitigates liver injury induced obesity”
  • Jose Christian Perez, Ph.D., The University of Texas Health Science Center  - “How intestinal cells sense a human gut fungal pathobiont”
  • Dongyin Guan, Ph.D., Baylor College of Medicine, “Interplay between circadian clocks and liver cirrhosis”
  • Joud Hajjar, M.D., Baylor College of Medicine - "Microbiome in common variable immunodeficiency" (renewal) 

2021 Pilot Awardees

  • Xiangsheng Zuo, M.D., Ph.D., The University of Texas M.D. Anderson Cancer Center - “Targeting PPAR-d for gastric cancer prevention”
  • Natalia Khalaf, M.D., Baylor College of Medicine - “Predicting risk of long-term complications of acute pancreatitis in U.S. veteran population”
  • Andrea McAlester-Hill, Ph.D., Baylor College of Medicine - “Dietary lipid regulation of intestinal tissue repair”
  • Sara Di Rienzi, Ph.D., Baylor College of Medicine - “Intestinal oxytocin in treatment of gut inflammation”
  • Joud Hajjar, M.D., Baylor College of Medicine - "Microbiome in common variable immunodeficiency"
  • Jill Weatherhead, M.D., MSc, Baylor College of Medicine, “Ascaris larvae - host intestinal epithelial interface”
  • Kanchan Singh, Ph.D., The University of Texas Health Science Center - "Adenosine signaling in pancreatitis associated with pancreatic ductal obstruction initiated by mutant Kras" 

2020 Pilot Awardees

  • Maya Balakrishnan, M.D., Baylor College of Medicine - “Nonalcoholic Fatty Liver Disease in Women”
  • Deepavali Chakravarti, Ph.D., The University of Texas M.D. Anderson Cancer Center - “Telomere dysfunction drives inflammation through YAP”
  • Gregory Guthrie, Ph.D., Baylor College of Medicine - “Parenteral lipid effect during obstructive cholestasis”
  • Fong Lam, M.D., Baylor College of Medicine - “Platelets in APAP-induced Hepatotoxicity”
  • Mimi Tan, M.D., M.P.H., Baylor College of Medicine, “Predicting Risk of Gastric Intestinal Metaplasia”

2019 Pilot Feasibility Awardees

  • James Collins, Ph.D., Baylor College of Medicine - “Adaptation and Spread of VRE”
  • Bo Hu, Ph.D., University of Texas Health Science Center - "Structure of H. pylori Cag Type IV Secretion System"
  • Cullen Taniguchi, M.D., Ph.D., The University of Texas MD Anderson Cancer Center - “HIF2-Induced Wnt5a in Small Intestine Regeneration”
  • Mimi Tan, M.D., Baylor College of Medicine - “Predicting Risk of Gastric Intestinal Metaplasia”
  • Hongtao "Alex" Wang, M.D., Baylor College of Medicine - “Activating LRH-1 using oral lauric acid in treating IBD”
  • Rajesh Shah, M.D., Baylor College of Medicine - “Molecular Predictors of Response to anti-TNF Therapy”
  • Bhanu Priya Ganesh, Ph.D., University of Texas Heath Science Center - “Role of Gut Mast Cells in Post-Stroke Inflammation”

2018 Pilot Feasibility Awardees 

  • Hongtao Wang, Ph.D., Baylor College of Medicine - “Targeting nuclear receptor LRH-1 in treating IBD”
  • Tae Jin, Ph.D., University of Texas Health Science Center - "Role of miR-155 in human hepatocellular carcinoma"
  • Beatrice Bissig-Choisat, Ph.D., Baylor College of Medicine - “Role of PNPLA3 polymorphism in NAFLD using humanized mice”
  • Emily Mace, Ph.D., Baylor College of Medicine - “Gut microbiome and innate immune cell development”
  • Bo Hu, Ph.D., University of Texas Health Science Center - “Structure of Helicobacter pylori Cag type IV System”
  • Zheng Sun, Ph.D., Baylor College of Medicine - “Central circadian clock controls liver metabolism”
  • Sasirekha Ramani, Ph.D., Baylor College of Medicine - “Human Milk Oligosaccharides as Norovirus Antivirals”
  • Yun Nancy Huang, Ph.D., Texas A&M University - “Epigenetic regulation of Tregs during IBD pathogenesis”
  • Faith Ihekweazu, M.D., Baylor College of Medicine - “Bacteroides ovatus’ Role during Epithelial Inflammation”
  • Melinda Engevik, Ph.D., Baylor College of Medicine - “Serotonin in GI physiology”

2017 Pilot Feasibility Awardees

  • Jessica Bowser, Ph.D., The University of Texas Health Science Center - “Adenosine A2B receptor signaling protects chromosome stability in inflammatory bowel disease: a therapeutic target for improving mucosal healing?”
  • Xiaohong Bi, Ph.D., University of Texas Health Science Center - "The Role of Mucus Phosphatidylcholine in the Pathogenesis of Ulcerative Colitis"
  • Jian Chen, Ph.D., MD Anderson Cancer Center - “Deregulated TGF-β signaling in stem cell-associated liver injury”
  • Silke Paust, Ph.D., Baylor College of Medicine - “Generation Of A Novel Humanized Mouse Model To Evaluate The Human Microbiome – Immune Response Relationship”
  • Geoffrey Preidis, M.D., Ph.D., Baylor College of Medicine - “Persistent Epigenetic Changes in Early Undernutrition”
  • Allison Speer, M.D., The University of Texas Health Science Center - “Optimizing the Motility of Tissue-Engineered Intestine”
  • Aaron Thrift, Ph.D., Baylor College of Medicine - “Application of Natural Language Processing to Identify Dysplasia among a National Cohort of Veterans with Barrett’s Esophagus”

2016 Pilot Feasibility Awardees

  • David Durgan, Ph.D., Baylor College of Medicine - “Examining effects of sympathetic stimulation of the gut on OSA-induced hypertension”
  • Geoffrey Preidis, M.D., Ph.D., Baylor College of Medicine - "The Malnourished Microbiome, Steatosis, and Metabolism"
  • Sarah Blutt, Ph.D., Baylor College of Medicine - “Role of microbial factors on in vitro enterohepatic signaling”
  • Hamed Jafar-Nejad, M.D., Baylor College of Medicine - “Negative regulation of JAG1 by glycosylation:towards a mechanism-based therapy for Alagille syndrome”
  • Jennifer Auchtung, Ph.D., Baylor College of Medicine - “Effects of the microbiome on gastrointestinal homeostasis”
  • Jun-ichi Abe, M.D., Ph.D., The University of Texas MD Anderson Cancer Center - “The role of MAGl1 in inflammatory bowel disease”
  • Venugopal Venna, Ph.D., The University of Texas Health Science Center - “The forgotten GI infection: the aging microbiota”

2015 Pilot Feasibility Awardees

  • Jennifer M. Bailey, M.A., Ph.D., UT-Houston Medical School - “Critical Mechanisms Underlying Pancreatic Regeneration: A Unique Purpose For p120 Catenin.”
  • Sue Crawford, Ph.D., Assistant Professor, Department of Molecular Virology and Microbiology, Baylor College of Medicine - "Chylomicron Alteration by Enteric Pathogens."
  • Gretchen Diehl, Ph.D., Assistant Professor, Alkek Center for Metagenomics and Microbiome Research, Department of Molecular Virology and Microbiology, Baylor College of Medicine - “Identifying a role for mononuclear phagocyte sensing of microbiota species to promote intestinal healing.”
  • David Durgan, Ph.D., Instructor, Baylor College of Medicine, Dept. of Anesthesiology - “Role of the gut microbiome in the development of hypertension associated with obstructive sleep apnea.”
  • Jason Heaney, Ph.D., Assistant Professor, Department of Molecular and Human Genetics, Baylor College of Medicine - “A transcriptional role for IL-33 in intestinal epithelial cell tissue repair response.”
  • Kendal Hirschi, Ph.D., Professor, Pediatrics-Nutrition, Baylor College of Medicine - “Gut Permeability determines Dietary miRNA absorption.”
  • Jennifer K. Spinler, Ph.D., Instructor, Baylor College of Medicine, Scientist, Microbial Genetics & Genomics, Texas Children's Microbiome Center - “Reuterin – Investigation of a novel signaling mechanism in gut-microbial health.”
  • Yuxiang Sun, M.D., Ph.D., Assistant Professor, USDA/ARS Children’s Nutrition Research Center - “The role of the ghrelin receptor in dietary insult-induced steatohepatitis.”
  • Melissa Suter, Ph.D., Instructor, OB/GYN Department, Baylor College of Medicine - “Investigating the incidence of metabolic endotoxemia associated with gestational diabetes.”
  • M. Elizabeth Tessier, M.D., Pediatric Gastroenterology, Hepatology and Nutrition Fellow, Baylor College of Medicine/ Texas Children's Hospital - “Enterohepatic autocrine signals in gut microbial pathogenesis.”
  • Daoyan Wei, Ph.D., Assistant Professor, Department Gastroenterology Hepatology & Nutrition, The University of Texas MD Anderson Cancer Center - “The role and mechanisms of Kruppel-like factor 4 in pancreatic Injury.”

2014 Pilot Feasibility Awardees

  • Joseph Alcorn, Ph.D., Associate Professor, Pediatrics-Neonatology, UT Medical School, UTHSC
  • Rohan Bhavane, Ph.D., Sr. Research Scientist, Pediatrics, Radiology, Baylor College of Medicine - Texas Children's Hospital
  • Emily Corse, Ph.D., Assistant Professor, Immunology, MD Anderson Cancer Center
  • Xinfu Guan, Ph.D., Assistant Professor, Pediatrics, CNRC, Baylor College of Medicine
  • Jason Hou, M.D., Assistant Professor, Baylor College of Medicine
  • Ergun Sahin, M.D., Ph.D., Assistant Professor, Molecular Physiology and Biophysics, Baylor College of Medicine, Huffington Center on Aging
  • Jennifer Spinler, Ph.D., Instructor, Pathology-Immunology, Baylor College of Medicine - Texas Children's Hospital
  • Ruth Wooton-Kee, Ph.D., Postdoctoral Associate, Molecular and Cellular Biology,Baylor College of Medicine
  • Seung-Hee Yoo, Ph.D., Assistant Professor, Biochemistry & Molecular Biology, UTHSC, Altered Gut Microbiota and GI, Physiology In Circadian Clock Deficient Mice

2013 Pilot Feasibility Awardees

  • Rebecca Berdeaux, Ph.D., Assistant Professor, University of Texas Health Science Center
  • Charles Darkoh, Ph.D., Assistant Professor, Center for Infectious Diseases, School of Public Health, Division, University of Texas Health Science Center
  • Moreshwar Desai, M.D., Assistant Professor, Pediatrics - Critical Care, Baylor College of Medicine
  • Jeremy Schaefer, Ph.D., Assistant Professor, Diagnostic and Biomedical Sciences, UTHSC School of Dentistry
  • Robert Tsai, M.D., Ph.D., Associate Professor, Institute of Biosciences and Technology, Texas A&M University System Health Science Center
  • Xiangcang Ye, Ph.D., Assistant Professor, Cancer Biology, MD Anderson Cancer Center
  • Yong Zhou, Instructor, Integrative Biology and Pharmacology, The University of Texas Health Science Center
  • Donna L. White, Ph.D., M.P.H, Assistant Professor, Medicine - Health Services Research & Gastroenterology and Hepatology, Baylor College of Medicine

2012 Pilot Feasibility Awardees

  • Karl-Dimiter Bissig, M.D., Ph.D., Center for Cell and Gene Therapy, Stem Cells and Regenerative Medicine Center, Department of Molecular and Cellular Biology, Baylor College of Medicine
  • Zheng Jake Chen, Ph.D., Assistant Professor, Biochemistry and Molecular Biology, UTHealth
  • Yeonseok Chung, Ph.D., Center for Immunology and Autoimmune Diseases, Institute of Molecular Medicine, UTHealth, The University of Texas Medical School at Houston
  • Sanjiv Harpavat, M.D., Ph.D., Clinical Postdoctoral Fellow, Pediatrics - GI, Liver, & Nutrition, Baylor College of Medicine
  • Joe Hyser, Ph.D., Instructor, Molecular Virology & Microbiology, Baylor College of Medicine
  • Fasiha Kanwal, M.D., MSHS, Associate Professor, Medicine - Gastroenterology and Hepatology, Baylor College of Medicine
  • Yuying Liu, Ph.D., Assistant Professor, Department of Pediatrics – Gastroenterology, UTHealth
  • Anthony Maresso, Ph.D., Assistant Professor, Molecular Virology and Microbiology, Baylor College of Medicine
  • Oluyinka O. Olutoye, M.D, Ph.D., Co-Director, Texas Children's Fetal Center, Co-Surgical Director, Neonatal ECMO Program, Associate Professor of Surgery, Pediatrics and Obstetrics and Gynecology, Baylor College of Medicine
  • Xin Xie, Ph.D., Instructor, Molecular and Cellular Biology, Baylor College of Medicine

2011 Pilot Feasibility Awardees

  • Joseph M. Hyser, Ph.D., Pediatric GI Post-Doctoral Fellow, Estes Laboratory, Baylor College of Medicine
  • Hongzhen Hu, Ph.D., Assistant Professor, Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston
  • Sun Kuk Kwon, Ph.D., Assistant Professor, Center for Molecular Imaging, Institute of Molecular Medicine, The University of Texas Health Science Center
  • Muralidhar Premkumar, MBBS, DCH, DNB, MRCPCH, Assistant Professor, Neonatal-Perinatal Medicine, Section of Neonatology, Department of Pediatrics, Baylor College of Medicine
  • Kimberly S. Schluns, Ph.D., Associate Professor, Dept. of Immunology, Unit 901, UT MD Anderson Cancer Center
  • Heidi Karpen, M.D., Department of Pediatrics, Division of Neonatology, Baylor College of Medicine/Texas Children's Hospital

2010 Pilot Feasibility Awardees

  • Yongde Luo, Ph.D., Assistant Professor, Center for Cancer and Stem Cell Biology, Texas A&M Health Science Center
  • Paula Hertel, M.D., Assistant Professor of Pediatrics, GI, Hepatology, and Nutrition, Texas Children’s Hospital Liver Center, Baylor College of Medicine
  • Bin He, Ph.D., Instructor, Department of Molecular and Cellular Biology, Baylor College of Medicine
  • Yongcheng Song, Ph.D., Assistant Professor, Department of Pharmacology, Baylor College of Medicine
  • Michael Lorenz, Ph.D., Assistant Professor, Microbiology and Molecular Genetics, UT Health Science Center at Houston
  • Alexander Kots, Ph.D.Instructor, Cell Signaling, UT-Houston Institute of Molecular Medicine
  • Ryan Himes, M.D., GI Fellow, Department of Pediatrics, Baylor College of Medicine
  • Donna L. White, Ph.D., MPH, Assistant Professor, Sections of Health Services Research & GI and Hepatology, Baylor College of Medicine
  • Shumei Song, M.D., Ph.D., Assistant Professor, GI, Hepatology & Nutrition, U.T. MDACC
  • Shujuan Pan, Ph.D., Instructor, Department of Pathology, Baylor College of Medicine
  • Richard Kellermayer, M.D., Ph.D., Instructor, Pediatric GI, Hepatology & Nutrition, Baylor College of Medicine

2009 Pilot Feasibility Awardees

  • Junlan Zhang, M.D., Ph.D., Assistant Professor, Internal Medicine, GI, Hepatology and Nutrition, UT Medical School at Houston
  • Bruno P. Chumpitazi, M.D., MPH, Assistant Professor, Pediatrics, Baylor College of Medicine
  • Yuko Mori-Akiyama, M.D., Assistant Professor, Pathology, Baylor College of Medicine
  • Stacey Moore-Olufemi, M.D., Pediatric Surgery Fellow, UT Medical School at Houston
  • Yuying Liu, Ph.D., Research Scientist, Pediatric GI, UT Medical School at Houston.

2008 Pilot Feasibility Awardees

  • Nicola Brunetti-Pierri, M.D., Assistant Professor, Molecular and Human Genetics, Baylor College of Medicine
  • Yuko Mori-Akiyama, M.D., Assistant Professor, Molecular Genetics, UT-MD Anderson Cancer Center
  • Karen S. Uray, Ph.D.Assistant Professor, Pediatric Surgery, UT Medical School at Houston.
  • Sushovan Guha, M.D., Ph.D.Assistant Professor, GI-Hepatology, & Nutrition, UT MD Anderson Cancer Center
  • Anne M. Hutson-Walker, Ph.D., Instructor, Pediatrics – GI Hepatology & Nutrition, Baylor College of Medicine
  • Shumei Song M.D., Ph.D., Assistant Professor, GI Medicine & Nutrition, UT MD Anderson Cancer Center
  • Sharmila Anandasabapathy, M.D., Assistant Professor. GI, Hepatology and Nutrition, UT-MD Anderson Cancer Center

2005 Pilot Feasibility Awardees

  • Charles S. Cox, Jr., M.D., Pediatric Surgery, UT-Houston Medical School
  • Romi Ghose, Ph.D., Pediatrics-Gastroenterology & Nutrition, Baylor College of Medicine
  • W.A. Hoogerwerf, M.D., Internal Medicine, UT Medical Branch, Galveston
  • Noah Shroyer, Ph.D., Molecular & Human Genetics, Baylor College of Medicine
  • Christina Thaller, MSc, Biochemistry & Molecular Biology, Baylor College of Medicine
  • Alfredo Torres, Ph.D., Microbiology & Immunology; Pathology, UT Medical Branch, Galveston
  • Ming Zhang, Ph.D., Assistant Molecular & Cellular Biology, Baylor College of Medicine

2004 Pilot Feasibility Awardees

  • Sarah Blutt, Ph.D., Molecular Virology and Microbiology, Baylor College of Medicine
  • Hashem El-Serag, M.D., MPH, Medicine, Baylor College of Medicine, VAMC
  • Michael Helmrath, M.D., Pediatric Surgery, Baylor College of Medicine
  • Milan Jamrich, Ph.D., Molecular & Cellular Biology, Baylor College of Medicine

2003 Pilot Feasibility Awardees

  • Emily Robinson, M.D., Surgery, UT-Houston Medical School
  • Jiaren Sun, M.D., Ph.D., Microbiology, UT Medical Branch, Galveston
  • LuAnn Thompson-Snipes, Ph.D., Pathology, Baylor College of Medicine
  • James Versalovic, M.D., Ph.D., Pathology, Baylor College of Medicine
  • Sundararajah Thevananther, Ph.D., Pediatrics, Baylor College of Medicine
  • Xiao-Feng Yang, M.D., Ph.D., Medicine-Rheumatology, Baylor College of Medicine

2002 Pilot Feasibility Awardees

  • Benny Chang, Ph.D., Molecular and Cellular Biology, Baylor College of Medicine
  • Li Fang, Ph.D., Neuroscience, UT Medical Branch, Galveston
  • Charles Madden, Ph.D., Molecular Virology and Microbiology, Baylor College of Medicine
  • Pauline Ward, Ph.D., Molecular and Cellular Biology, Baylor College of Medicine
  • Yoshio Yamaoka, M.D., Ph.D., Medicine-GI, Baylor College of Medicine

2001 Pilot Feasibility Awardees

  • Michael Barry, Ph.D., Human and Molecular Genetics and Center for Gene Therapy, Baylor College of Medicine
  • Max Ciarlet, Ph.D., Molecular Virology and Microbiology, Baylor College of Medicine
  • John F. Di Mari, Ph.D., Medicine-GI, UT Medical Branch, Galveston
  • Sunghoon Kim, M.D., Surgery, UT Medical Branch, Galveston
  • Chantal A. Rivera, Ph.D., Pediatrics, Baylor College of Medicine
  • Mei X. Wu, M.D., Ph.D., Pathology, Baylor College of Medicine

2000 Pilot Feasibility Awardees

  • Mariella De Biasi, Ph.D., Neuroscience, Baylor College of Medicine
  • Hala El-Zimaity, M.D., Medicine-GI, Baylor College of Medicine
  • Ka Bian, M.D., Ph.D., Integrative Biology and Pharmacology, UT-Houston Medical School
  • Krishna Rajarathnam, Ph.D., Biological Chemistry and Genetics and Center for Structural Biology, UT Medical Branch, Galveston

1999 Pilot Feasibility Awardees

  • Russel Broaddus, M.D., Ph.D., Pathology, Baylor College of Medicine
  • Antonella Casola, M.D., Pediatrics, UT Medical Branch, Galveston
  • Andrew P. Morris, Ph.D., Integrative Biology & Pharmacology, UT-Houston Medical School
  • Antonia R. Sepulveda, M.D., Ph.D., Medicine-GI and Pathology, Baylor College of Medicine