Positions
- Professor
-
Pathology & Immunology
Baylor College of Medicine
Houston, TX US
- Member
-
Dan L Duncan Comprehensive Cancer Center
Baylor College of Medicine
Houston, Texas United States`
Education
- Ph.D. from McGill University
- 01/1997 - Montreal, Canada
- Advanced Training from Fox Chase Cancer Center
- 01/1994 - Philadelphia, PA United States
- Advanced Training from McGill University
- 01/1992 - Montreal, Canada
- Advanced Training from University Of Vermont
- 01/1990 - Burlington, VT United States
- Advanced Training from University Of Vermont
- 01/1990 - Burlington, VT United States
- Advanced Training from University Of Vermont
- 01/1988 - Burlington, VT United States
- Advanced Training from University Of Ibadan College Of Medicine
- 01/1986 - Ibadan, Nigeria
- Advanced Training from University Of Ibadan College Of Medicine
- 01/1986 - Ibadan, Nigeria
- Advanced Training from University Of Ibadan College Of Medicine
- 01/1981 - Ibadan, Nigeria
- M.D. from University Of Ibadan
- 01/1980 - Ibadan, Nigeria
Websites
Selected Publications
- Sun GS, Adesina AM, Rauch RA, Metry DW "A 2-month-old girl with an enlarging lesion of the nasal root. Nasal glioma.." Pediatr Ann. 2009 Feb;38(2):76, 79. Pubmed PMID: 19263781
- Yu L, Baxter PA, Voicu H, Gurusiddappa S, Zhao Y, Adesina A, Man TK, Shu Q, Zhang YJ, Zhao XM, Su JM, Perlaky L, Dauser R, Chintagumpala M, Lau CC, Blaney SM, Rao PH, Leung HC, Li XN "A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo.." Neuro-oncology. 2010 Jun;12(6):580-94. Pubmed PMID: 20511191
- Yu L, Baxter PA, Zhao X, Liu Z, Wadhwa L, Zhang Y, Su JM, Tan X, Yang J, Adesina A, Perlaky L, Hurwitz M, Idamakanti N, Police SR, Hallenbeck PL, Blaney SM, Chintagumpala M, Hurwitz RL, Li XN "A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models.." Neuro-oncology. 2011 Jan;13(1):14-27. Pubmed PMID: 21075780
- York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, O'Malley BW "Ablation of Steroid Receptor Coactivator-3 Resembles the Human CACT Metabolic Myopathy.." Cell Metab.. 2012 May 2;15(5):752-63. Pubmed PMID: 22560224
- Fruhman G, Landsverk ML, Lotze TE, Hunter JV, Wangler MF, Adesina AM, Wong LJ, Scaglia F "Atypical presentation of Leigh syndrome associated with a Leber hereditary optic neuropathy primary mitochondrial DNA mutation.." Mol. Genet. Metab.. 2011 Jun;103(2):153-60. Pubmed PMID: 21414825
- Murphy JW, Schafer F, Casadevall A, Adesina A "Antigen-induced protective and nonprotective cell-mediated immune components against Cryptococcus neoformans.." Infect. Immun.. 1998 Jun;66(6):2632-9. Pubmed PMID: 9596727
- Takei H, Dauser R, Su J, Chintagumpala M, Bhattacharjee MB, Jones J, Adesina AM "Anaplastic ganglioglioma arising from a Lhermitte-Duclos-like lesion. Case report.." J. Neurosurg.. 2007 Aug;107(2):137-42. Pubmed PMID: 18459885
- Takei H, Adesina AM, Mehta V, Powell SZ, Langford LA "Atypical teratoid/rhabdoid tumor of the pineal region in an adult.." J. Neurosurg.. 2010 Aug;113(2):374-9. Pubmed PMID: 19911885
- Adesina AM, Vallyathan V, McQuillen EN, Weaver SO, Craighead JE "Bronchiolar inflammation and fibrosis associated with smoking. A morphologic cross-sectional population analysis.." Am. Rev. Respir. Dis.. 1991 Jan;143(1):144-9. Pubmed PMID: 1986671
- Mukherjee A, Peterson JE, Sandberg G, Takei H, Adesina A, Goodman JC, Powell S "Central nervous system pathology in fatal swine-origin influenza A H1N1 virus infection in patients with and without neurological symptoms: an autopsy study of 15 cases.." Acta Neuropathol.. 2011 Sep;122(3):371-3. Pubmed PMID: 21744080
- Tandan R, Taylor R, Adesina A, Sharma K, Fries T, Pendlebury W "Benign autosomal dominant syndrome of neuronal Charcot-Marie-Tooth disease, ptosis, parkinsonism, and dementia.." Neurology. 1990 May;40(5):773-9. Pubmed PMID: 2184381
- Sutton DA, Wickes BL, Romanelli AM, Rinaldi MG, Thompson EH, Fothergill AW, Dishop MK, Elidemir O, Mallory GB, Moonnamakal SP, Adesina AM, Schecter MG "Cerebral aspergillosis caused by Aspergillus granulosus.." J. Clin. Microbiol.. 2009 Oct;47(10):3386-90. Pubmed PMID: 19710280
- Takei H, Bhattacharjee MB, Adesina AM "Chordoid glioma of the third ventricle: Report of a case with cytologic features and utility during intraoperative consultation.." Acta Cytol..;50(6):691-6. Pubmed PMID: 17152286
- Seto ES, Proud M, Adesina AM, Su J, Muscal E "Clinical Reasoning: An 8-year-old girl with multifocal brain lesions and cerebral edema.." Neurology. 2012 May 8;78(19):e117-21. Pubmed PMID: 22565572
- Adeleye AO, Okolo CA, Akang EE, Adesina AM "Cerebral pleomorphic xanthoastrocytoma associated with NF1: an updated review with a rare atypical case from Africa.." Neurosurg Rev. 2012 Jul;35(3):313-9. Pubmed PMID: 22020543
- Hampton DE, Adesina A, Chodosh J "Conjunctival sporotrichosis in the absence of antecedent trauma.." Cornea. 2002 Nov;21(8):831-3. Pubmed PMID: 12410047
- Takei H, Dauser RC, Adesina AM "Cytomorphologic characteristics, differential diagnosis and utility during intraoperative consultation for medulloblastoma.." Acta Cytol..;51(2):183-92. Pubmed PMID: 17425200
- Yang Z, McMahon CJ, Smith LR, Bersola J, Adesina AM, Breinholt JP, Kearney DL, Dreyer WJ, Denfield SW, Price JF, Grenier M, Kertesz NJ, Clunie SK, Fernbach SD, Southern JF, Berger S, Towbin JA, Bowles KR, Bowles NE "Danon disease as an underrecognized cause of hypertrophic cardiomyopathy in children.." Circulation. 2005 Sep 13;112(11):1612-7. Pubmed PMID: 16144992
- Leech RW, Brumback RA, Poduslo SE, Schiffer R, Adesina A "Dementia: the University of Oklahoma autopsy experience.." J Okla State Med Assoc. 2001 Nov;94(11):507-11. Pubmed PMID: 11729597
- Li XN, Shu Q, Su JM, Adesina AM, Wong KK, Perlaky L, Antalffy BA, Blaney SM, Lau CC "Differential expression of survivin splice isoforms in medulloblastomas.." Neuropathol. Appl. Neurobiol.. 2007 Feb;33(1):67-76. Pubmed PMID: 17239009
- Blackstock R, Buchanan KL, Adesina AM, Murphy JW "Differential regulation of immune responses by highly and weakly virulent Cryptococcus neoformans isolates.." Infect. Immun.. 1999 Jul;67(7):3601-9. Pubmed PMID: 10377145
- Adesina AM, Dooley N, Yong VW, Nalbantoglu J "Differential role for protein kinase C-mediated signaling in the proliferation of medulloblastoma cell lines.." Int. J. Oncol.. 1998 Apr;12(4):759-68. Pubmed PMID: 9499434
- Takei H, Yogeswaren ST, Wong KK, Mehta V, Chintagumpala M, Dauser RC, Lau CC, Adesina AM "Expression of oligodendroglial differentiation markers in pilocytic astrocytomas identifies two clinical subsets and shows a significant correlation with proliferation index and progression free survival.." J. Neurooncol.. 2008 Jan;86(2):183-90. Pubmed PMID: 17690840
- Wong KK, Chang YM, Tsang YT, Perlaky L, Su J, Adesina A, Armstrong DL, Bhattacharjee M, Dauser R, Blaney SM, Chintagumpala M, Lau CC "Expression analysis of juvenile pilocytic astrocytomas by oligonucleotide microarray reveals two potential subgroups.." Cancer Res.. 2005 Jan 1;65(1):76-84. Pubmed PMID: 15665281
- Shu Q, Wong KK, Su JM, Adesina AM, Yu LT, Tsang YT, Antalffy BC, Baxter P, Perlaky L, Yang J, Dauser RC, Chintagumpala M, Blaney SM, Lau CC, Li XN "Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.." Stem Cells. 2008 Jun;26(6):1414-24. Pubmed PMID: 18403755
- Adesina AM, Dunn ST, Moore WE, Nalbantoglu J "Expression of p27kip1 and p53 in medulloblastoma: relationship with cell proliferation and survival.." Pathol. Res. Pract.. 2000;196(4):243-50. Pubmed PMID: 10782468
- Takei H, Eldin KW, Adesina AM, Bhattacharjee MB "Fatal Epstein-Barr virus meningitis: an autopsy report.." Clin. Neuropathol..;25(3):115-22. Pubmed PMID: 16719407
- Verma A, Tandan R, Adesina AM, Pendlebury WW, Fries TJ, Bradley WG "Focal neuropathy preceding chronic inflammatory demyelinating polyradiculoneuropathy by several years.." Acta Neurol. Scand.. 1990 Jun;81(6):516-21. Pubmed PMID: 2171295
- Adesina AM, Nguyen Y, Mehta V, Takei H, Stangeby P, Crabtree S, Chintagumpala M, Gumerlock MK "FOXG1 dysregulation is a frequent event in medulloblastoma.." J. Neurooncol.. 2007 Nov;85(2):111-22. Pubmed PMID: 17522785
- Szigeti K, Wiszniewski W, Saifi GM, Sherman DL, Sule N, Adesina AM, Mancias P, Papasozomenos SCh, Miller G, Keppen L, Daentl D, Brophy PJ, Lupski JR "Functional, histopathologic and natural history study of neuropathy associated with EGR2 mutations.." Neurogenetics. 2007 Nov;8(4):257-62. Pubmed PMID: 17717711
- Adesina AM, Nguyen Y, Guanaratne P, Pulliam J, Lopez-Terrada D, Margolin J, Finegold M "FOXG1 is overexpressed in hepatoblastoma.." Hum. Pathol.. 2007 Mar;38(3):400-9. Pubmed PMID: 17217994
- Thompson MC, Fuller C, Hogg TL, Dalton J, Finkelstein D, Lau CC, Chintagumpala M, Adesina A, Ashley DM, Kellie SJ, Taylor MD, Curran T, Gajjar A, Gilbertson RJ "Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations.." J. Clin. Oncol.. 2006 Apr 20;24(12):1924-31. Pubmed PMID: 16567768
- López-Terrada D, Gunaratne PH, Adesina AM, Pulliam J, Hoang DM, Nguyen Y, Mistretta TA, Margolin J, Finegold MJ "Histologic subtypes of hepatoblastoma are characterized by differential canonical Wnt and Notch pathway activation in DLK+ precursors.." Hum. Pathol.. 2009 Jun;40(6):783-94. Pubmed PMID: 19200579
- Rednam S, Scheurer ME, Adesina A, Lau CC, Okcu MF "Glutathione S-transferase P1 single nucleotide polymorphism predicts permanent ototoxicity in children with medulloblastoma.." Pediatr Blood Cancer. 2013 Apr;60(4):593-8. Pubmed PMID: 23065688
- Mayer RR, Warmouth GM, Troxell M, Adesina AM, Kass JS "Glioblastoma multiforme of the conus medullaris in a 28-year-old female: a case report and review of the literature.." Clin Neurol Neurosurg. 2012 Apr;114(3):275-7. Pubmed PMID: 22040726
- Sriram S, Topham DJ, Carroll L, Shenoy M, Adesina A, Craighead JE "In vivo administration of TNF-alpha prevents EMC-M virus induced viral encephalitis.." Int. Immunol.. 1991 Jul;3(7):641-5. Pubmed PMID: 1655003
- Adesina A, Chumba D, Nelson AM, Orem J, Roberts DJ, Wabinga H, Wilson M, Rebbeck TR "Improvement of pathology in sub-Saharan Africa.." Lancet Oncol.. 2013 Apr;14(4):e152-7. Pubmed PMID: 23561746
- Szigeti K, Sule N, Adesina AM, Armstrong DL, Saifi GM, Bonilla E, Hirano M, Lupski JR "Increased blood-brain barrier permeability with thymidine phosphorylase deficiency.." Ann. Neurol.. 2004 Dec;56(6):881-6. Pubmed PMID: 15562405
- Verma A, Bradley WG, Adesina AM, Sofferman R, Pendlebury WW "Inclusion body myositis with cricopharyngeus muscle involvement and severe dysphagia.." Muscle Nerve. 1991 May;14(5):470-3. Pubmed PMID: 1651449
- Trachte AL, Suthers SE, Lerner MR, Hanas JS, Jupe ER, Sienko AE, Adesina AM, Lightfoot SA, Brackett DJ, Postier RG "Increased expression of alpha-1-antitrypsin, glutathione S-transferase pi and vascular endothelial growth factor in human pancreatic adenocarcinoma.." Am. J. Surg.. 2002 Dec;184(6):642-7; discussi. Pubmed PMID: 12488200
- Topham DJ, Adesina A, Shenoy M, Craighead JE, Sriram S "Indirect role of T cells in development of polioencephalitis and encephalomyelitis induced by encephalomyocarditis virus.." J. Virol.. 1991 Jun;65(6):3238-45. Pubmed PMID: 1674548
- Adesina AM "Intraoperative consultation in the diagnosis of pediatric brain tumors.." Arch. Pathol. Lab. Med.. 2005 Dec;129(12):1653-60. Pubmed PMID: 16329737
- Lalani SR, Vladutiu GD, Plunkett K, Lotze TE, Adesina AM, Scaglia F "Isolated mitochondrial myopathy associated with muscle coenzyme Q10 deficiency.." Arch. Neurol.. 2005 Feb;62(2):317-20. Pubmed PMID: 15710863
- Adesina AM, Lopez-Terrada D, Wong KK, Gunaratne P, Nguyen Y, Pulliam J, Margolin J, Finegold MJ "Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathways.." Hum. Pathol.. 2009 Jun;40(6):843-53. Pubmed PMID: 19200578
- Wong KK, Tsang YT, Chang YM, Su J, Di Francesco AM, Meco D, Riccardi R, Perlaky L, Dauser RC, Adesina A, Bhattacharjee M, Chintagumpala M, Lau CC "Genome-wide allelic imbalance analysis of pediatric gliomas by single nucleotide polymorphic allele array.." Cancer Res.. 2006 Dec 1;66(23):11172-8. Pubmed PMID: 17145861
- Humphries WE, Satyan KB, Relyea K, Kim ES, Adesina AM, Chintagumpala M, Jea A "Low-grade myofibroblastic sarcoma of the sacrum.." J Neurosurg Pediatr. 2010 Sep;6(3):286-90. Pubmed PMID: 20809714
- Fridley JS, Chamoun RB, Whitehead WE, Curry DJ, Luerssen TG, Adesina A, Jea A "Malignant rhabdoid tumor of the spine in an infant: case report and review of the literature.." Pediatr Neurosurg. 2009;45(3):237-43. Pubmed PMID: 19521139
- Takei H, Nguyen Y, Mehta V, Chintagumpala M, Dauser RC, Adesina AM "Low-level copy gain versus amplification of myc oncogenes in medulloblastoma: utility in predicting prognosis and survival. Laboratory investigation.." 2009 Jan;3(1):61-5. Pubmed PMID: 19119907
- Yoo JH, Rivera A, Naeini RM, Yedururi S, Bayindir P, Megahead H, Fuller GN, Suh JS, Adesina AM, Hunter JV "Melanotic paraganglioma arising in the temporal horn following Langerhans cell histiocytosis.." Pediatr Radiol. 2008 May;38(5):571-4. Pubmed PMID: 18196230
- Cheema ZF, Cannon TC, Leech R, Brennan J, Adesina A, Brumback RA "Medullomyoblastoma: case report.." J. Child Neurol.. 2001 Aug;16(8):598-9. Pubmed PMID: 11510933
- Jiang YH, Fang P, Adesina AM, Furman P, Johnston JJ, Biesecker LG, Brown CW "Molecular characterization of co-occurring Duchenne muscular dystrophy and X-linked oculo-facio-cardio-dental syndrome in a girl.." Am. J. Med. Genet. A. 2009 Jun;149(6):1249-52. Pubmed PMID: 19449433
- Adesina AM "Molecular heterogeneity in medulloblastoma with implications for differing tumor biology.." J. Child Neurol.. 1999 Jul;14(7):411-7. Pubmed PMID: 10573461
- Venkova K, Dunn ST, Adesina AM, Meerveld BG, Greenwood-Van Meerveld B "Neuromuscular dysfunction in the jejunum and colon of human leukocyte antigen B27 transgenic rats.." J. Pharmacol. Exp. Ther.. 2000 Apr;293(1):60-6. Pubmed PMID: 10734153
- Szigeti K, Wong LJ, Perng CL, Saifi GM, Eldin K, Adesina AM, Cass DL, Hirano M, Lupski JR, Scaglia F "MNGIE with lack of skeletal muscle involvement and a novel TP splice site mutation.." J. Med. Genet.. 2004 Feb;41(2):125-9. Pubmed PMID: 14757860
- Hotez PJ, Asojo OA, Adesina AM "Nigeria: ground zero" for the high prevalence neglected tropical diseases."." PLoS Negl Trop Dis. 2012 Jul;6(7):e1600. Pubmed PMID: 22860138
- Castellino RC, De Bortoli M, Lin LL, Skapura DG, Rajan JA, Adesina AM, Perlaky L, Irwin MS, Kim JY "Overexpressed TP73 induces apoptosis in medulloblastoma.." BMC Cancer. 2007;7:127. Pubmed PMID: 17626635
- De Bortoli M, Castellino RC, Lu XY, Deyo J, Sturla LM, Adesina AM, Perlaky L, Pomeroy SL, Lau CC, Man TK, Rao PH, Kim JY "Medulloblastoma outcome is adversely associated with overexpression of EEF1D, RPL30, and RPS20 on the long arm of chromosome 8.." BMC Cancer. 2006;6:223. Pubmed PMID: 16968546
- Fouladi M, Blaney SM, Poussaint TY, Freeman BB, McLendon R, Fuller C, Adesina AM, Hancock ML, Danks MK, Stewart C, Boyett JM, Gajjar A "Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors: a pediatric brain tumor consortium study.." Cancer. 2006 Nov 1;107(9):2291-7. Pubmed PMID: 17019740
- Locher DH, Adesina A, Wolf TC, Imes CB, Chodosh J "Postoperative Rhizopus scleritis in a diabetic man.." J Cataract Refract Surg. 1998 Apr;24(4):562-5. Pubmed PMID: 9584256
- Chamoun RB, Whitehead WE, Dauser RC, Luerssen TG, Okcu MF, Adesina AM, Jea A "Primary disseminated intradural malignant peripheral nerve sheath tumor of the spine in a child: case report and review of the literature.." Pediatr Neurosurg. 2009;45(3):230-6. Pubmed PMID: 19521138
- Ellezam B, Theeler BJ, Luthra R, Adesina AM, Aldape KD, Gilbert MR "Recurrent PIK3CA mutations in rosette-forming glioneuronal tumor.." Acta Neuropathol.. 2012 Feb;123(2):285-7. Pubmed PMID: 21997360
- Al-Shamy G, Relyea K, Adesina A, Whitehead WE, Curry DJ, Luerssen TG, Jea A "Solid variant of aneurysmal bone cyst of the thoracic spine: a case report.." J Med Case Reports. 2011;5(1):261. Pubmed PMID: 21718507
- Morrow PL, Adesina A "Ski fatalities in Vermont.." J Trauma. 1991 Jan;31(1):150. Pubmed PMID: 1986126
- Takei H, Adesina AM, Powell SZ "Solitary subependymal giant cell astrocytoma incidentally found at autopsy in an elderly woman without tuberous sclerosis complex.." Neuropathology. 2009 Apr;29(2):181-6. Pubmed PMID: 18673443
- Roberts DJ, Wilson ML, Nelson AM, Adesina AM, Fleming KA, Milner D, Guarner J, Rebbeck TR, Castle P, Lucas S "The good news about cancer in developing countries--pathology answers the call.." Lancet. 2012 Feb 25;379(9817):712. Pubmed PMID: 22364759
- Takei H, Adesina AM, Bhattacharjee MB "The Azzopardi phenomenon.." Arch. Pathol. Lab. Med.. 2007 Apr;131(4):518. Pubmed PMID: 17425376
- Li JY, Langford LA, Adesina A, Bodhireddy SR, Wang M, Fuller GN "The high mitotic count detected by phospho-histone H3 immunostain does not alter the benign behavior of angiocentric glioma.." Brain Tumor Pathol. 2012 Jan;29(1):68-72. Pubmed PMID: 21892765
- Adesina AM, Nalbantoglu J, Cavenee WK "p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma.." Cancer Res.. 1994 Nov 1;54(21):5649-51. Pubmed PMID: 7923211
- Mhatre M, Nguyen A, Kashani S, Pham T, Adesina A, Grammas P "Thrombin, a mediator of neurotoxicity and memory impairment.." Neurobiol. Aging. 2004 Jul;25(6):783-93. Pubmed PMID: 15165703
- Snell BE, Adesina A, Wolfla CE "Unicameral bone cyst of a cervical vertebral body and lateral mass with associated pathological fracture in a child. Case report and review of the literature.." J. Neurosurg.. 2001 Oct;95(2):243-5. Pubmed PMID: 11599845
- Shu Q, Antalffy B, Su JM, Adesina A, Ou CN, Pietsch T, Blaney SM, Lau CC, Li XN "Valproic Acid prolongs survival time of severe combined immunodeficient mice bearing intracerebellar orthotopic medulloblastoma xenografts.." Clin. Cancer Res.. 2006 Aug 1;12(15):4687-94. Pubmed PMID: 16899619
- Rao VY, Hwang SW, Adesina AM, Jea A "Thrombosed traumatic aneurysm of the occipital artery: a case report and review of the literature.." J Med Case Rep. 2012;6(1):203. Pubmed PMID: 22804804
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