George Allen Edwards, Ph.D.
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George Allen Edwards, Ph.D.
Postdoctoral Associate
Positions
- Postdoctoral Associate
-
Neuroscience
Baylor College of Medicine
Education
- PhD from The University of Texas Health Science Center in Houston
- 12/2019 - Houston, Texas United States
- Neuroscience
- MS from The University of Texas Health Science Center in Houston
- 05/2013 - Houston, Texas United States
- Neuroscience
- BS from Texas A&M University
- 05/2009 - College Station, Texas United States
- Biology
- AS from Blinn College
- 05/2006 - Brenham, Texas United States
- Science
Selected Publications
- Edwards III G.A., Zhao J., Dask P.K., Soto C., Moreno-Gonzalez I. "Traumatic brain injury induces tau aggregation and spreading." J of Neurotrauma. 2020 Jan 1;37(1):80-92. Pubmed PMID: 31317824
- Edwards G. III, Gamez N., Armijo E., Kramm C., Morales R., Taylor-Presse K., Schulz P.E., Soto C., Moreno-Gonzalez I. "Peripheral Delivery of Neural Precursor Cells Ameliorates Parkinson’s Disease-Associated Pathology." Cells. 2019 Oct;8(11):pii: E1359. Pubmed PMID: 31671704
- Edwards G. III, Moreno-Gonzalez I. "Early Diagnostic Approaches for Alzheimer’s disease." Recent Research Advances in Alzheimer’s disease, Semantic Books. 2019;
- Edwards III G., Gamez N., Escobedo Jr. G., Calderon O., Moreno-Gonzalez I. "Modifiable Risk Factors for Alzheimer’s Disease.." Front. Aging Neurosci.. 2019 Jun 24;11(146) Pubmed PMID: 31293412
- Kwon S., Moreno-Gonzalez I., Taylor-Presse K., Edwards III G., Gamez N., Calderon O., Zhu B., Velasquez F.C., Soto C., Sevick-Muraca E.M. "Impaired Peripheral Lymphatic Function and Cerebrospinal Fluid Outflow in a Mouse Model of Alzheimer's Disease." J Alzheimers Dis.. 2019;69(2):585-593. Pubmed PMID: 31104026
- Moreno-Gonzalez I.*, Edwards G. III*, Salvadores N., Shahnawaz M., Diaz-Espinoza R., Soto C. "Molecular interaction between type II diabetes and Alzheimer’s disease through cross-seeding of protein misfolding." Mol Psychiatry. 2017 Sep;22(9):1327-1334. Pubmed PMID: 28044060
- Edwards G. III, Moreno-Gonzalez I., Soto C. "Amyloid-beta and tau pathology following repetitive mild traumatic brain injury." Biochem Biophys Res Commun. 2017 Feb 19;483(4):1137-1142. Pubmed PMID: 27492070
- Montgomery K.S., Edwards G. III, Levites Y., Kumar A., Myers C.E., Gluck M.A., Setlow B., Bizon J.L. "Deficits in hippocampal-dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis." Hippocampus. 2016 Apr;26(4):455-71. Pubmed PMID: 26418152
- Montgomery K.S., Simmons R.K., Edwards G. 3rd, Nicolle M.M., Gluck M.A., Myers C.E., Bizon J.L. "Novel age-dependent learning deficits in a mouse model of Alzheimer’s disease: implications for translational research." Neurobiol Aging. 2011 Jul;32(7):1273-85. Pubmed PMID: 19720431
- Armijo E., Edwards G. III, Flores A., Vera J., Shahnawaz M., Moda F., Gonzalez C., Sanhueza M., Soto C. "Induced pluripotent stem cell-derived neural precursors improve behavior, synaptic plasticity and pathology in a mouse model of Alzheimer’s disease." Cells. 2021;10(7):1802. Pubmed PMID: 34359972
- Morales R., Bravo-Alegria J., Moreno-Gonzalez I., Duran-Aniotz C., Gamez N., Edwards G. III, Soto C. "Transmission of cerebral amyloid pathology by peripheral administration of misfolded Aβ aggregates.." Mol Psychiatry. 2021 Oct;26(10):5690-5701. Pubmed PMID: 34002023
- Qingfen Q., Manalo J.M., Sun H., Zhang Y., Song A., Wen A.Q., Wen Y.E., Chen C., Liu H., Cui Y., Nemkov T., Reisz J.A., Edwards III G., Perreira F.A., Kellems R.E., Soto C., D'Alessandro A., Xia Y. "Erythrocyte adenosine A2B receptor combats age-related cognitive and auditory functional decline by promoting hypoxic and metabolic reprogramming.." PLoS Biol. 2021 Jun;2021(19):6. Pubmed PMID: 34138843
- Moreno-Gonzalez I., Edwards G. III, Hasan O., Gamez N., Schulz J., Fernandez-Valenzuela J.J., Gutierrez A., Soto C., Schulz P.E. "Longitudinal assessment of tau pathology by 18F-THK-5351 PET imaging: A histological, biochemical, and behavioral study.." Diagnostics. 2021;11(10):1874. Pubmed PMID: 34679572
- Moreno-Gonzalez I., Edwards G. III, Morales R., Duran-Aniotz C., Escobedo Jr. G., Marquez M., Pumarola M., Soto C. "Aged cattle brain displays Alzheimer's disease-like pathology and promotes brain amyloidosis in a transgenic animal model.." Front. Aging Neurosci.. 2022 Jan;31(13) Pubmed PMID: 35173603
Funding
- Co-Investigator - #NIRG-394284 (01/01/2016 - 01/01/2019) Grant funding from Alzheimer's Association
- PET imaging to detect Alzheimer’s-like pathology after brain injury
- The Effect of Traumatic Brain Injury on Tau Pathology by a Potential Seeding Mechanism - #F31 NS103499-01 (05/30/2017 - 08/29/2019) Grant funding from NINDS
- TMEM106B as a modifier of lysosome function in age-related tauopathies - #T32 NS043124-18 (07/01/2020 - 07/01/2022) Grant funding from NIH Brain Disorders and Development Training Grant
- TMEM106B as a modifier of lysosome function in age-related tauopathies - #3P01AG066606 (07/01/2022 - 07/01/2023) Grant funding from Program Project Grant - 02W1 Diversity Supplement
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