Jaime Manuel Reyes
Picture
Jaime Manuel Reyes
Graduate Student
Positions
- Graduate Student
-
Molecular and Human Genetics
Baylor College of Medicine
Houston, TX US
Education
- BS from Massachusetts Institute of Technology
- 06/2013 - Cambridge, Massachusetts United States
Honors & Awards
- Gilliam Fellow
- Howard Hughes Medical Institute (09/2018)
Professional Interests
- Aging, computational biology, bioinformatics, stem cell biology
Selected Publications
- "BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment." ; Pubmed PMID: 28673542
- "Large DNA methylation nadirs anchor chromatin loops maintaining hematopoietic stem cell identity.." ; Pubmed PMID: 32386543
- "Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells in vivo." ; Pubmed PMID: 29617651
- "Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome." ; Pubmed PMID: 34092059
- "Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor." ; Pubmed PMID: 34429321
- "Tissue- Biased Expansion of DNMT3A-Mutant Clones Associated with Conserved Epigenetic Erosion." ; Pubmed PMID: 32673568
- "Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms." ; Pubmed PMID: 29249691
- "Synthetic lethal and resistance interactions with BET bromodomain inhibitors in triple-negative breast cancer." ; Pubmed PMID: 32416067
- "Enhancer invasion shapes MYCN dependent transcriptional amplification in neuroblastoma." ; Pubmed PMID: 29379199
- "Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis." ; Pubmed PMID: 26438361
Languages
Spanish
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