Research

  1. Baylor College of Medicine
  2. Research
  3. ATC Core Labs
  4. Metabolomics Core
  5. Publications

Metabolomics Core Publications

Master
Heading

Selected Publications Supported by the Metabolomics Core

Content

2024

  1. Talwar C, Davuluri GVN, Kamal AHM, Coarfa C, Han SJ, Veeraragavan S, Parsawar K, Putluri N, Hoffman K, Jimenez P, Biest S, Kommagani R. Identification of distinct stool metabolites in women with endometriosis for non-invasive diagnosis and potential for microbiota-based therapies. Med. 2025 Feb 14;6(2):100517. doi: 10.1016/j.medj.2024.09.006. Epub 2024 Oct 11. PMID: 39395412; PMCID: PMC11830556.
  2. Sharma P, Jain T, Sorgen A, Iyer S, Tarique M, Roy P, Kurtom S, Sethi V, Bava EP, Gutierrez-Garcia AK, Vaish U, Suresh DS, Sahay P, Edwards D, Afghani J, Putluri S, Reddy KRK, Amara CS, Kamal AHM, Fodor A, Dudeja V. Smoking-induced gut microbial dysbiosis mediates cancer progression through modulation of anti-tumor immune response. iScience. 2025 Feb 11;28(3):112002. doi: 10.1016/j.isci.2025.112002. PMID: 40104059; PMCID: PMC11914281.
  3. Hudobenko J, Di Gesù CM, Mooz PR, Petrosino J, Putluri N, Ganesh BP, Rebeles K, Blixt FW, Venna VR, McCullough LD. Maternal dysbiosis produces long-lasting behavioral changes in offspring. Mol Psychiatry. 2024 Oct 23. doi: 10.1038/s41380-024-02794-0. Epub ahead of print. PMID: 39443733.
  4. Li Y, Yadollahi P, Essien F, Putluri V, Chandra S, Kami Reddy KR, Kamal A, Putluri N, Abdurrahman LM, Ruiz-Echartea E, Ernste K, Trivedi A, Vazquez-Perez J, Hudson WH, Decker W, Patel R, Osman AA, Kheradmand F, Lai SY, Myers JN, Skinner HD, Coarfa C, Lee K, Jain A, Malovannaya A, Frederick MJ, Sandulache VC. Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer. bioRxiv [Preprint]. 2024 Oct 21:2024.10.17.618907. doi: 10.1101/2024.10.17.618907. PMID: 39484602; PMCID: PMC11526855.
  5. Kami Reddy KR, Piyarathna DWB, Park JH, Putluri V, Amara CS, Kamal AHM, Xu J, Kraushaar D, Huang S, Jung SY, Eberlin LS, Johnson JR, Kittles RA, Ballester LY, Parsawar K, Siddiqui MM, Gao J, Langer Gramer A, Bollag RJ, Terris MK, Lotan Y, Creighton CJ, Lerner SP, Sreekumar A, Kaipparettu BA, Putluri N. Mitochondrial reprogramming by activating OXPHOS via glutamine metabolism in African American patients with bladder cancer. JCI Insight. 2024 Sep 10;9(17):e172336. doi: 10.1172/jci.insight.172336. PMID: 39253977; PMCID: PMC11385078.
  6. Meena JK, Wang JH, Neill NJ, Keough D, Putluri N, Katsonis P, Koire AM, Lee H, Bowling EA, Tyagi S, Orellana M, Dominguez-Vidaña R, Li H, Eagle K, Danan C, Chung HC, Yang AD, Wu W, Kurley SJ, Ho BM, Zoeller JR, Olson CM, Meerbrey KL, Lichtarge O, Sreekumar A, Dacso CC, Guddat LW, Rejman D, Hocková D, Janeba Z, Simon LM, Lin CY, Pillon MC, Westbrook TF. MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer. Cancer Discov. 2024 Sep 4;14(9):1699-1716. doi: 10.1158/2159-8290.CD-22-0649. PMID: 39193992; PMCID: PMC11372365.
  7. Yang S, Tang W, Azizian A, Gaedcke J, Ohara Y, Cawley H, Hanna N, Ghadimi M, Lal T, Sen S, Creighton CJ, Gao J, Putluri N, Ambs S, Hussain P. MIF/NR3C2 axis regulates glucose metabolism reprogramming in pancreatic cancer through MAPK-ERK and AP-1 pathways. Carcinogenesis. 2024 Aug 12;45(8):582-594. doi: 10.1093/carcin/bgae025. PMID: 38629149; PMCID: PMC11317528.
  8. Yazdani A, Samms-Vaughan M, Saroukhani S, Bressler J, Hessabi M, Tahanan A, Grove ML, Gangnus T, Putluri V, Kamal AHM, Putluri N, Loveland KA, Rahbar MH. Metabolomic Profiles in Jamaican Children With and Without Autism Spectrum Disorder. J Autism Dev Disord. 2024 Jul 20. doi: 10.1007/s10803-024-06485-1. Epub ahead of print. PMID: 39033254.
  9. Godfrey WH, Cho K, Deng X, Ambati CSR, Putluri V, Mostafa Kamal AH, Putluri N, Kornberg MD. Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism. bioRxiv [Preprint]. 2024 Jun 28:2024.06.23.600101. doi: 10.1101/2024.06.23.600101. PMID: 38979375; PMCID: PMC11230282.
  10. Elbialy A, Kappala D, Desai D, Wang P, Fadiel A, Wang SJ, Makary MS, Lenobel S, Sood A, Gong M, Dason S, Shabsigh A, Clinton S, Parwani AV, Putluri N, Shvets G, Li J, Liu X. Patient-Derived Conditionally Reprogrammed Cells in Prostate Cancer Research. Cells. 2024 Jun 8;13(12):1005. doi: 10.3390/cells13121005. PMID: 38920635; PMCID: PMC11201841.
  11. Rasouli S, Dakic A, Wang QE, Mitchell D, Blakaj DM, Putluri N, Li J, Liu X. Noncanonical functions of telomerase and telomeres in viruses-associated cancer. J Med Virol. 2024 May;96(5):e29665. doi: 10.1002/jmv.29665. PMID: 38738582.
  12. Czerniak B, Lee S, Jung SY, Kus P, Bondaruk J, Lee J, Jaksik R, Putluri N, Dinh K, Cogdell D, Chen H, Wang Y, Chen J, Nevai N, Dinney C, Mendelsohn C, McConkey D, Behringer R, Guo C, Wei P, Kimmel M. Inferring Bladder Cancer Evolution from Mucosal field Effects by Whole-Organ Spatial Mutational, Proteomic, and Metabolomic Mapping. Res Sq [Preprint]. 2024 Apr 10:rs.3.rs-3994376. doi: 10.21203/rs.3.rs-3994376/v1. PMID: 38659962; PMCID: PMC11042420.
  13. Murthy D, Dutta D, Attri KS, Samanta T, Yang S, Jung KH, Latario SG, Putluri V, Huang S, Putluri N, Park JH, Kaipparettu BA. CD24 negativity reprograms mitochondrial metabolism to PPARα and NF-κB-driven fatty acid β-oxidation in triple-negative breast cancer. Cancer Lett. 2024 Apr 10;587:216724. doi: 10.1016/j.canlet.2024.216724. Epub 2024 Feb 17. PMID: 38373689; PMCID: PMC11068061.
  14. Amara CS, Kami Reddy KR, Yuntao Y, Chan YS, Piyarathna DWB, Dobrolecki LE, Shih DJH, Shi Z, Xu J, Huang S, Ellis MJ, Apolo AB, Ballester LY, Gao J, Hansel DE, Lotan Y, Hodges HC, Lerner SP, Creighton CJ, Sreekumar A, Zheng WJ, Msaouel P, Kavuri SM, Putluri N. The IL6/JAK/STAT3 signaling axis is a therapeutic vulnerability in SMARCB1-deficient bladder cancer. Nat Commun. 2024 Feb 14;15(1):1373. doi: 10.1038/s41467-024-45132-2. PMID: 38355560; PMCID: PMC10867091.
  15. Wang DH, Fujita Y, Dono A, Rodriguez Armendariz AG, Shah M, Putluri N, Pichardo-Rojas PS, Patel CB, Zhu JJ, Huse JT, Parker Kerrigan BC, Lang FF, Esquenazi Y, Ballester LY. The genomic alterations in glioblastoma influence the levels of CSF metabolites. Acta Neuropathol Commun. 2024 Jan 19;12(1):13. doi: 10.1186/s40478-024-01722-1. PMID: 38243318; PMCID: PMC10799404.
  16. Ahn S, Park JH, Grimm SL, Piyarathna DWB, Samanta T, Putluri V, Mezquita D, Fuqua SAW, Putluri N, Coarfa C, Kaipparettu BA. Metabolomic Rewiring Promotes Endocrine Therapy Resistance in Breast Cancer. Cancer Res. 2024 Jan 16;84(2):291-304. doi: 10.1158/0008-5472.CAN-23-0184. PMID: 37906431; PMCID: PMC10842725.