Chunmei Wang, Ph.D. - Primary Investigator
I started my scientific career from exploring the androgens actions in the gonads (as a Ph.D. candidate), to unravelling neuroendocrine mechanisms for sex differences in energy balance (as a postdoctoral fellow). These previous experiences equipped me with sufficient knowledge and skills in studying functions of sex hormones in the central nervous system. My current goal is to expand my research to explore brain estrogenic actions in the regulation of energy balance under different physiological conditions, including sex differences in response to nutritional challenges, female body weight and feeding controls in menopause, pregnancy and lactation. I hope that results from my research will identify rational targets for developing therapeutic strategies for neuroendocrine disorders in females, specifically the dysregulation of sex hormones and associated metabolic diseases.
Sanika Jossy - Research Technician
I graduated from the University of Texas at Austin in May 2023 with a Bachelor of Science in Human Biology and a minor in Kinesiology and Health Education. During undergrad, I studied cancer cell metabolism, particularly the inhibitory effects of ND-646 on fatty acid synthesis in various prostate cancer cell lines. This research experience was invaluable and solidified my interest in the broad and fascinating field of metabolism. Additionally, it led me to join the Wang Lab where I now have the exciting opportunity to study how the brain controls and regulates metabolism through various mouse models. In my free time, I love to read classics, play volleyball, and teach Zumba!
Darah Scruggs-Threat - Graduate Student
I graduated from the University of Houston-Main in 2019 with my bachelor’s degree in Biology with a minor in Medicine and Society. I received my master’s degree in Cell Systems and Anatomy from the University of Texas Health Science Center-San Antonio in 2021. During my graduate work I studied adiponectin signaling and liver metabolism under the direction of Dr. Lily Dong. My project involved determining the localization of adiponectin receptor 2 under various dietary conditions and its impact on adiponectin signaling. I developed an appreciation for cell signaling and metabolic research during this time. I worked at MD Anderson from 2021 to 2023 as a research assistant in the lab of Dr. Michael Andreeff. I worked on determining resistance mechanisms of acute myeloid leukemia to a cMyc degrader using various in vitro techniques, including mitochondrial respiration assays and flow cytometry. The skills and knowledge gained during and after my master’s drove me to pursue my doctorate. I began my journey at Baylor fall of 2023 with the interest of delving more into how the brain regulates our metabolism. This led to me to join Dr. Wang’s lab where I study how estrogen signaling in the brain impacts metabolism.