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Triple Labeling for Amyloid, Microglia, and a Therapeutic Anti-Aβ Antibody
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Thioflavine-S staining similar to that shown here was used by student Angie Chiang to measure fibrillar amyloid before and after treatment in our APP transgenic mice. Related Link: Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer’s disease
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General Use
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Biochemistry
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Diethylamine extraction for soluble Aß measurement from Liz Eckman
Formic acid extraction for total Aß measurement from Linda and Steve Younkin
Immunoprecipitation of brain proteins
Proteinase K tissue DNA extraction
SDS/Formic acid extraction for Aß measurement from Linda and Steve Younkin
TBS / TBS-X / Guanidine extraction for Aß measurement from Guojun Bu
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Histology
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