Publications from the THCCC
Kanwal, F., Khaderi, S., Singal, A. G., Marrero, J. A., Loo, N., Asrani, S. K., Amos, C. I., Thrift, A. P., Gu, X., Luster, M., Al-Sarraj, A., Ning, J., & El-Serag, H. B. (2023). Risk factors for HCC in contemporary cohorts of patients with cirrhosis. Hepatology (Baltimore, Md.), 77(3), 997–1005. https://doi.org/10.1002/hep.32434
Pubmed PMID: 35229329; PubMed Central ID: 9433461; Publication Status: Published
Thrift, A. P., Kanwal, F., Liu, Y., Khaderi, S., Singal, A. G., Marrero, J. A., Loo, N., Asrani, S. K., Luster, M., Al-Sarraj, A., Ning, J., Tsavachidis, S., Gu, X., Amos, C. I., & El-Serag, H. B. (2023). Risk stratification for hepatocellular cancer among patients with cirrhosis using a hepatic fat polygenic risk score. PloS one, 18(2), e0282309. https://doi.org/10.1371/journal.pone.0282309
Pubmed PMID: 36854015; PubMed Central ID: 9974109; Publication Status: Published
Kanwal, F., Khaderi, S., Singal, A. G., Marrero, J. A., Asrani, S. K., Amos, C. I., Thrift, A. P., Kramer, J. R., Yu, X., Cao, Y., Luster, M., Al-Sarraj, A., Ning, J., & El-Serag, H. B. (2023). Risk Stratification Model for Hepatocellular Cancer in Patients With Cirrhosis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 21(13), 3296–3304.e3. https://doi.org/10.1016/j.cgh.2023.04.019
Pubmed PMID: 37390101; PubMed Central ID: 10661677; Publication Status: Published
El-Serag, H. B., Akhdar, G., Thrift, A. P., Luster, M., Khaderi, S., Alsarraj, A., Duong, H., & Kanwal, F. (2023). Bioimpedance analysis predicts the etiology of cirrhosis in a prospective cohort study. Hepatology communications, 7(10), e0253. https://doi.org/10.1097/HC9.0000000000000253
Pubmed PMID: 37695087; PubMed Central ID: 10497244; Publication Status: Published
El-Serag, H., Kanwal, F., Ning, J., Powell, H., Khaderi, S., Singal, A. G., Asrani, S., Marrero, J. A., Amos, C. I., Thrift, A. P., Luster, M., Alsarraj, A., Olivares, L., Skapura, D., Deng, J., Salem, E., Najjar, O., Yu, X., Duong, H., Scheurer, M. E., … Kaochar, S. (2024). Serum biomarker signature is predictive of the risk of hepatocellular cancer in patients with cirrhosis. Gut, gutjnl-2024-332034. Advance online publication. https://doi.org/10.1136/gutjnl-2024-332034
Pubmed PMID: 38365278; PubMed Central ID: 11327383; Publication Status: Published
Thrift, A. P., Kanwal, F., Lim, H., Duong, H., Liu, Y., Singal, A. G., Khaderi, S., Asrani, S. K., Amos, C. I., & El-Serag, H. B. (2024). PNPLA3, Obesity, and Heavy Alcohol Use in Cirrhosis Patients May Exert a Synergistic Increase Hepatocellular Carcinoma Risk. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 22(9), 1858–1866.e4. https://doi.org/10.1016/j.cgh.2024.04.006
Pubmed PMID: 38729396; PubMed Central ID: Not available; Publication Status: Published
El-Serag, H. B., Jin, Q., Tayob, N., Salem, E., Luster, M., Alsarraj, A., Khaderi, S., Singal, A. G., Marrero, J. A., Asrani, S. K., & Kanwal, F. (2024). HES V2.0 outperforms GALAD for detection of HCC: A phase 3 biomarker study in the United States. Hepatology (Baltimore, Md.), 10.1097/HEP.0000000000000953. Advance online publication. https://doi.org/10.1097/HEP.0000000000000953
Pubmed PMID: 38899967; PubMed Central ID: Not available; Publication Status: Published
Feng Z, Marrero JA, Khaderi S, Singal AG, Kanwal F, Loo N, Beretta L, Ning J, El-Serag HB. Design of the Texas Hepatocellular Carcinoma Consortium Cohort Study. Am J Gastroenterol. 2019 Mar;114(3):530-532. doi: 10.14309/ajg.0000000000000068.
PubMed PMID: 30699099; Publication Status: Published
El-Serag HB, Kanwal F, Feng Z, Marrero JA, Khaderi S, Singal AG; Texas Hepatocellular Carcinoma Consortium. Risk Factors for Cirrhosis in Contemporary Hepatology Practices-Findings From the Texas Hepatocellular Carcinoma Consortium Cohort. Gastroenterology. 2020 Jul;159(1):376-377. doi: 10.1053/j.gastro.2020.03.049. Epub 2020 Mar 29.
PubMed PMID: 32234536; PubMed Central ID: PMC8375364; Publication Status: Published
Kanwal F, Khaderi S, Singal AG, Marrero JA, Loo N, Asrani SK, Amos CI, Thrift AP, Gu X, Luster M, Al-Sarraj A, Ning J, El-Serag HB. Risk factors for HCC in contemporary cohorts of patients with cirrhosis. Hepatology. 2022 Mar 1:10.1002/hep.32434. doi: 10.1002/hep.32434. Epub ahead of print.
PubMed PMID: 35229329; PubMed Central ID: PMC9433461; Publication Status: Published
Other Publications
AG Singal, El-Serag H, Hepatocellular Carcinoma From Epidemiology to Prevention: Translating Knowledge into Practice. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association. 2015 Nov. 13. 12. 2140-51.
PubMed PMID: 26284591; PubMed Central ID: PMC4618036; Publication Status: Published
Coarfa C, Fu L, Lee C, Sreekumar A, Putluri N, Moore DD, Voicu H, Kettner NM, Katchy CA, Finegold MJ, Circadian Homeostasis of Liver Metabolism Suppresses Hepatocarcinogenesis.. Cancer cell. 2016 Dec 12. 30. 6. 909-924.
PubMed PMID: 27889186; PubMed Central ID: PMC5695235; Publication Status: Published
N Tayob, Z Feng, K Do, F Stingo, A Lok, A Bayesian screening approach for hepatocellular carcinoma using multiple longitudinal biomarkers.. Biometrics. 2017 May 8.
PubMed PMID: 28482112; PubMed Central ID: PMC5677596; Publication Status: Published
Borowiak M, Hu J, Parsons DW, Bissig-Choisat B, Muzny D, Yang D, Vasudevan SA, Hampton OA, Legras XD, Thompson PA, Chen LL, Finegold M, Zorman B, Sumazin P, López-Terrada D, Gaber MW, Huang YH, Pautler RG, Kettlun-Leyton C, Bissig KD, Goss JA, Shi Y, Doddapaneni HV, Barzi M, Prakash MM, Hicks MJ, Lu Y, Mills GB, Amin MD, Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer.. Journal of hepatology. 2016 Aug. 65. 2. 325-33.
PubMed PMID: 27117591; PubMed Central ID: PMC5668139; Publication Status: Published
Singal AG, Rich NE, Parikh ND, Marrero JA, Tzartzeva K, Yopp A, Waljee AK, Obi J, Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis.. Gastroenterology. 2018 May. 154. 6. 1706-1718.e1.
PubMed PMID: 29425931; PubMed Central ID: PMC5927818; Publication Status: Published
Lok AS, Feng Z, Shen W, Ning J, Yuan Y, Model-free scoring system for risk prediction with application to hepatocellular carcinoma study.. Biometrics. 2018 Mar. 74. 1. 239-248.
PubMed PMID: 28742219; PubMed Central ID: PMC5785588; Publication Status: Published
Lok AS, Tayob N, Feng Z, Do KA, Improved Detection of Hepatocellular Carcinoma by Using a Longitudinal Alpha-Fetoprotein Screening Algorithm. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2016 Mar. 14. 3. 469-475.e2.
PubMed PMID: 26260109; PubMed Central ID: PMC4744807; Publication Status: Published
Desiderio R, Thrift AP, Asch SM, Kramer JR, Mapakshi S, Chu J, Chayanupatkul M, El-Serag HB, Kanwal F, Li L, Richardson PA, Natarajan Y, Risk of Hepatocellular Cancer in Patients With Non-Alcoholic Fatty Liver Disease.. Gastroenterology. 2018 Dec. 155. 6. 1828-1837.e2.
PubMed PMID: 30144434; PubMed Central ID: PMC6279617; Publication Status: Published
Pankowicz FP, Moore DD, Elsea SH, Wooton-Kee CR, Marini JC, Kim KH, Bissig-Choisat B, Lagor WR, Legras X, Barzi M, Martins CS, Bissig KD, Rapid Disruption of Genes Specifically in Livers of Mice Using Multiplex CRISPR/Cas9 Editing. Gastroenterology. 2018 Dec. 155. 6. 1967-1970.e6.
PubMed PMID: 30170115; PubMed Central ID: PMC6420307; Publication Status: Published
Ohsfeldt RL, Kum HC, Choi DT, Singal AG, Park S, Shen Y, Parikh ND, Hepatocellular Carcinoma Screening Is Associated With Increased Survival of Patients With Cirrhosis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2019 Apr. 17. 5. 976-987.e4.
PubMed PMID: 30616961; PubMed Central ID: PMC6431264; Publication Status: Published
Halm EA, Singal AG, Mejias C, Santini NO, Tiro JA, Waljee AK, Pechero W, Murphy CC, Marrero JA, Fullington H, McCallister K, Mailed Outreach Invitations Significantly Improve HCC Surveillance Rates in Patients With Cirrhosis: A Randomized Clinical Trial.. Hepatology (Baltimore, Md.). 2019 Jan. 69. 1. 121-130.
PubMed PMID: 30070379; PubMed Central ID: PMC6324997; Publication Status: Published
Loo N, Feng Z, Ning J, Marrero JA, Khaderi S, El-Serag HB, Beretta L, Singal AG, Kanwal F, Design of the Texas Hepatocellular Carcinoma Consortium Cohort Study.. The American journal of gastroenterology. 2019 Mar. 114. 3. 530-532.
PubMed PMID: 30699099; PubMed Central ID: Publication Status: Published
El-Serag HB, Kramer JR, Dai J, Asch SM, Li L, Yu X, Natarajan Y, Kanwal F, Effect of Metabolic Traits on the Risk of Cirrhosis and Hepatocellular Cancer in Nonalcoholic Fatty Liver Disease.. Hepatology (Baltimore, Md.). 2020 Mar. 71. 3. 808-819.
PubMed PMID: 31675427; PubMed Central ID: Publication Status: Published
Marrero JA, Texas Consortium., Feng Z, Kanwal F, El-Serag HB, Singal AG, Khaderi S, Risk Factors for Cirrhosis in Contemporary Hepatology Practices-Findings From the Texas Hepatocellular Carcinoma Consortium Cohort.. Gastroenterology. 2020 Mar 29.
PubMed PMID: 32234536; PubMed Central ID: Publication Status: Published
Ning J, Feng Z, Li R, Li W, Semiparametric isotonic regression analysis for risk assessment under nested case-control and case-cohort designs. Statistical methods in medical research. 2019 Dec 22. 962280219893389.
PubMed PMID: 31868119; PubMed Central ID: Publication Status: In Press
Circulating Osteopontin and Prediction of Hepatocellular Carcinoma Development in a Large European Population. Cancer Prevention Research. 2016 Jun 23.
PubMed PMID: 27339170; PubMed Central ID: PMC5010922; Publication Status: Published
The THCCC is made possible by grant RP150587 from the Cancer Prevention and Research Institute of Texas, PI: Hashem B. El-Serag; P01 CA263025 from the National Cancer Institutes, PI: Hashem B. El-Serag; and RP220119 from the Cancer Prevention and Research Institute of Texas, PI Hashem B. El-Serag. It is also supported by U01 CA230997-01, PI: Fasiha Kanwal.
