Healthcare: Surgical Services

Superior Mesenteric Artery Syndrome

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Dr. Robert Southard, a Baylor Medicine surgeon, explains all about superior mesenteric artery syndrome (SMA).
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Superior Mesenteric Artery Syndrome (SMAS) is a rare but serious condition that affects the digestive tract. It occurs when the third portion of the duodenum (part of the small intestine) becomes compressed between the abdominal aorta and the superior mesenteric artery. This compression can lead to chronic gastrointestinal symptoms and, if untreated, may result in severe malnutrition.

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Causes of SMAS

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SMAS typically develops due to a narrowing of the angle between the abdominal aorta and the superior mesenteric artery—called the aortomesenteric angle. Several factors can contribute to this narrowing, including:

  • Rapid weight loss from surgery, restrictive diets or eating disorders
  • Abdominal trauma or previous surgeries that alter internal anatomy
  • Spinal abnormalities such as scoliosis or lordosis
  • Tumors or masses in the abdominal region
  • Prolonged immobilization in body casts or braces
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Scott Holmes
Illustration showing the anatomical relationship between the superior mesenteric artery (SMA), left renal vein, and small intestine. The left side of the image outlines the general position of these organs in the human abdomen, while the magnified section on the right highlights the SMA crossing over the left renal vein and passing anterior to the small intestine. Structures are color-coded for clarity: red for arteries, blue for veins, and pink for the small intestine.
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SMAS Diagnosis

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Diagnosing SMAS involves a detailed review of symptoms, medical history, and imaging studies. Common diagnostic tools include:

  • CT scans or MRI to visualize the aortomesenteric angle
  • Upper endoscopy to assess duodenal compression
  • Barium swallow studies to evaluate gastrointestinal function
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Treatment options for SMAS

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Treatment for SMAS varies based on severity and the patient’s overall health. Options include:

  • Nutritional support to restore weight and increase mesenteric fat padding
  • Nasoduodenal tube placement to bypass the obstruction temporarily
  • Surgical intervention if conservative treatments are unsuccessful. Common procedures include:
    • Duodenojejunostomy: rerouting the intestine to bypass the compressed area
    • Strong’s procedure: repositioning the duodenum to relieve compression
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SMA Patient Story

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How traveling to Houston healed Keri Carlson’s SMA Syndrome.

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