Altered metabolism is a hallmark of many diseases including cancer. The focus of the group is to understand metabolic vulnerabilities in cancer and develop therapeutic strategies that target the re-wired metabolic program and hence aid in blocking cancer progression. Furthermore, quantification of metabolites in biofluids can be used as non-invasive indicators for disease onset, progression or to monitor treatment response in patients. In light of all the above, CPSB students will learn to profile metabolome from patient samples, integrate the data with other OMICs datasets, study the consequence of key metabolic alterations using in vitro and in vivo cancer models, develop metabolite-based biomarkers and develop/test novel therapeutic strategies that target altered metabolic pathways.
Faculty Profiles: Metabolomics
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