One of the greatest advantages of cryo-EM relative to conventional structural biology techniques is its ability to analyze large, complex and flexible structures. Including many biologically important molecules that cannot be easily crystallized for x-ray or are too large for NMR. The Cryo-EM/Cryo-ET research at BCM focuses on technology development driven by a diverse spectrum of biological samples to achieve reliable atomic resolution structures of molecular machines, derive structures from conformationally variable machines and characterize the macromolecular machinery within intact cells in normal and pathological states.
Faculty Profiles: Cryo-EM and Cryo-Electron Tomography
Graduate School Admissions
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