Theme Leaders
Current Clinical Projects
1. Magnetic resonance based leg muscle perfusion to assess leg function in peripheral arterial disease [NIH K23, PI: Brunner]
2. Comparative effectiveness of physicians versus non-physicians for the delivery of outpatient Diabetes care: Implications for access to care under the Affordable Care Act [ADA, PI: Virani]
3. Comparative effectiveness of physicians vs. non-physicians for CHD care: implications for the Affordable Care Act [AHA, PI: Virani]
4. Identifying epidemiological risk factors for abdominal aortic aneurysm [NIH, Baylor Co- PI: Hoogeveen]
5. ARIC Central Atherosclerosis Laboratory [NIH, PI: Ballantyne]
6. Study of Health Outcomes of Weight-Loss (Look AHEAD) Trial [NIH, PI: Foreyt]
7. ARIC Neurocognitive Study (ARIC-NCS) [NIH, Baylor Co-PI: Ballantyne]
Current Basic Research Projects
1. Monocyte activation and the role of CD11c in obesity-linked metabolic syndrome [NIH, PI: Wu]
2. T cells, macrophages, chemokines, and adiposopathy in diet-induced obesity [NIH, PI: Ballantyne]
3. Role of blood-borne fibroblast precursors in ischemic cardiomyopathy [NIH, PI: Entman]
4. LRP1 and endothelial function [NIH, PI: Pi]
5. Signaling in endothelial growth & angiogenesis [NIH, PI: Pi]
6. Natural Substance Derivative DHNB is A Novel Xanthine Oxidase Inhibitor (NIH R21, PI: Chen)
7. Molecular Surgeon Research Training on Vascular Disease (NIH T32, PI: Chen)
8. Stanniocalcin-1, a novel anti-inflammatory protein (NIH R01, PI: Sheikh-Hamad; Co-I: Chen)
9. Chronic kidney disease adversely influences vascular functions (NIH R01, PI: Cheng, Co-I: Chen)
Research Faculty
Ashok Balasubramanyam, M.D. - Ketosis-prone diabetes, myogenesis and insulin action, HIV associated lipodystrophy
John Belmont, M.D. - CV genetics, cardiovascular malformations and connective tissue disorders
Gerd Brunner, M.D. - Peripheral arterial disease, MR imaging
Robert Bryan, Ph.D. - Cerebrovascular circulation, EDHF in cerebral arteries, traumatic brain injury, K channels
Larry Chan, M.D. - Genetics of atherosclerosis and lipid disorders, novel therapies for diabetes
Chu-Huang (Mendel) Chen, M.D. Ph.D. - Electronegative LDL, angiogenesis0
Katarzyna Cieslik, Ph.D. - Cardiac mesenchymal progenitors
Miguel Cruz, M.D. - Von Willebrand factor, thrombosis
Mark Entman, M.D. - Molecular mechanisms of cardiac injury and repair, inflammatory signaling
John Foreyt, Ph.D. - Behavioral medicine research, coronary heart disease
John Gaubatz, MS - Lipoprotein metabolism
Craig Hartley, Ph.D. - Ultrasonic instrumentation for CV research, coronary blood flow
Sandra Haudek, Ph.D. - Circulating monocytic fibroblast precursors, cardiac hypertrophy
Ron Hoogeveen, Ph.D. - Sterol and lipid metabolism, dyslipidemia
Jimmy Howell, M.D. - Cardiothoracic surgery; ischemic heart disease
Peter Jones, M.D. - Lipid-modifying drugs, obesity, clinical trials
William Lagor, Ph.D. - Regulation of lipid and lipoprotein metabolism
Veronica Lenge De Rosen, M.D. - Imaging of coronary vasculature
Vijay Nambi, M.D. - Peripheral arterial disease, vascular imaging, cardiac prevention
Henry Pownall, Ph.D. - Adipogenesis, metabolic syndrome, lipoproteins
Anilkumar Reddy, Ph.D. - Doppler and physiological monitoring of small animals, hypertrophy, cardiac remodeling
Todd Rosengart, M.D. - Cardiac regeneration, cardiac gene therapy, angiogenesis
Rolando Rumbaut, M.D. Ph.D. - Microvascular thrombosis, leukocyte trafficking
C. Wayne Smith, M.D. - Mechanisms of leukocyte accumulation in inflammation and tissue injury
Addison Taylor, M.D. Ph.D. - Hypertension, clinical pharmacology JoAnn Trial, Ph.D. Origins of fibroblasts in cardiac injury healing
Vinod Vijayan, Ph.D. - Ser/Thr phosphatases in platelet and endothelial activation
Salim Virani, M.D. Ph.D. - Cardiac prevention, cholesterol management
Huaizhu Wu, M.D. - Inflammation associated with dyslipidemia and obesity