Primary Faculty
Title: Appropriate perioperative antibiotic prophylaxis
Funding Agency: Agency for Healthcare Research and Quality
Role: Principal Investigator
Title: Outpatient antimicrobial stewardship
Funding Agency: PEW Charitable Trust
Role: Principal Investigator
Title: Addressing caregiver wellbeing and improving child development
Funding Agency: Episcopal Health Foundation
Role: Co-Principal Investigator
Title: Understanding the immune response changes to clinical interventions for Epstein-Barr virus infection prior to lymphoma development in children after organ transplants (UNEARTH)
Funding Agency: NIH
Role: Local Co-Principal Investigator
Title: Comparison of high vs. standard dose influenza vaccine in pediatric solid organ transplant recipients
Funding Agency: NIH
Role: Local Co-Investigator
Gail J. Demmler-Harrison, M.D.
Title: A retrospective follow-up study of the durability of antiviral therapy on long-term hearing and neurodevelopmental outcomes among patients treated for congenital cytomegalovirus infection as infants or toddlers
Funding Agency: NIH / NID-NIAID-CASG-CPIC
Role: Local Principal Investigator
Title: A real-world feasibility study to examine the epidemiology, clinical manifestations, responses to antiviral treatment, and health care utilization and health care costs of congenital cytomegalovirus infection in Texas, USA
Funding Agency: Moderna, Inc.
Role: Principal Investigator
Title: Pregnant people-infant linked longitudinal surveillance, Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET)
Funding Agency: Cooperative Agreement, Centers for Disease Control and Prevention, Houston Department of Health and Human Services
Role: Co-Investigator
Title: Development of a high throughput assay for rapid screening for congenital cytomegalovirus infection using dried blood spots, Phase 2
Funding Agency: NIH / NIDCD / National Institutes of Health Small Business and Microgen, Inc.
Role: Sub Award Principal Investigator
Title: Development of a high throughput assay for rapid screening for congenital cytomegalovirus infection using dried blood spots, Phase 1
Funding Agency: NIH / NIDCD / National Institutes of Health Small Business and Microgen, Inc.
Role: Sub Award Principal Investigator
Title: Identification of biomarkers of audiologic outcomes in congenital CMV infection
Funding Agency: NIH / NID- NIAID-CASG-CPIC
Role: Local Principal Investigator
Title: Health care utilization and health care costs associated with congenital CMV infection and disease
Funding Agency: Merck Sharpe & Dohme, Inc.
Role: Contract
Title: CNS-derived fetal extracellular vesicles for the non-invasive diagnosis of fetal CNS CMV infection
Funding Agency: NIH
Role: Co-Investigator
Title: Ripple effect of leadership: you can be a leader too
Funding Agency: Center for Research, Innovation and Scholarship in Medical Education, Texas Children’s Hospital
Role: Principal Investigator
Title: Vaccine and Treatment Evaluation Unit DMID (various studies)
Funding Agency: NIH
Role: National Co-Chair (Mpox vaccine trial); Site Principal Investigator (Novavax COVID-19 trial); Co-Investigator (others)
Title: Adolescent Vaccination Program (AVP)-various studies
Funding Agency: Cancer Prevention Research Institute of Texas (CPRIT)
Role: Co-Investigator
Title: The United States Pediatric Multicenter Pneumococcal Surveillance Study Group
Funding Agency: Pfizer, Inc.
Role: Co-Investigator
Title: Determination of the utility of Pfizer’s urine antigen test in children under 6 years of age with community-acquired pneumonia in the United States
Funding Agency: Pfizer, Inc.
Role: Co-Investigator
Title: Development of human adaptive immunity to Staphylococcus aureus
Funding Agency: NIH Sub-award
Role: Co-Investigator
Title: A phase 4 study using a test negative design to evaluate the effectiveness of a 20-valent pneumococcal conjugate vaccine against vaccine-type radiologically confirmed community-acquired pneumonia in adults less than or equal to 65 years of age
Funding Agency: Pfizer, Inc.
Role: Site PI
Title: Determination of the utility of Pfizer’s Urine antigen test in children 5 years of age or younger with community acquired pneumonia in the United States [and in Guatemala]
Funding Agency: Children’s Hospital of Colorado
Role: Site PI
Title: Ongoing Evaluation of the Impact of the Introduction of Pneumococcal Conjugate Vaccine (PCV-13) on the Incidence of Parapneumonic Empyema and other Invasive Pneumococcal Disease in Children and Adolescents in Orange County, California
Funding Agency: Children’s Hospital of Orange County
Role: Site PI
Title: The United States Pediatric Multicenter Pneumococcal Surveillance Study Group
Funding Agency: Pfizer, Inc.
Role: Principal Investigator
Title: Determination of the utility of Pfizer’s urine antigen test in children under 6 years of age with community-acquired pneumonia in the United States
Funding Agency: Pfizer, Inc.
Role: Principal Investigator
Title: Development of human adaptive immunity to Staphylococcus aureus
Funding Agency: NIH Sub-award
Role: Co-Investigator
Katherine Y. King, M.D., Ph.D.
Title: Impact of Infection and Inflammation on primitive hematopoiesis
Funding Agency: NIH / NHLBI
Role: Principal Investigator
Title: Modifiable drivers of expansion and malignant transformation from clonal hematopoiesis
Funding Agency: NIH / NCI
Role: Project 1 Leader, Administrative Core Co-Lead
Title: Medical Scientist Training Program
Funding Agency: NIH / NIGMS
Role: Co-Principal Investigator
Title: Diagnosing and studying pathogenic mechanisms of rare diseases
Funding Agency: Chan Zuckerberg Institute
Role: Co-Principal Investigator
Title: Mechanisms of Corynebacterium-Dolosigranulum interactions that shape human nasal microbiota
Funding Agency: NIH
Role: Principal Investigator
Title: Microbiome discovery and mechanisms to combat antibiotic resistance at mucosal surfaces
Funding Agency: NIH
Role: Multiple Principal Investigator (Britton, Lemon, Maresso, Patras)
Title: The impact of healthcare exposure on colonization with antiseptic tolerant staphylococci in children
Funding Agency: Agency for Healthcare Research and Quality
Role: Principal Investigator
Title: Development of human adaptive immunity to Staphylococcus aureus
Funding Agency: NIH / NIAID
Role: Co-Investigator (PI: Bubeck-Wardernburg, Fritz)
Title: Vaccine and Treatment Evaluation Units (VTEUs)
Funding Agency: NIH / NIAID
Role: Co-Investigator
Title: A prospective study of acute flaccid myelitis (AFM) natural history, risk factors and pathogenic mechanisms
Funding Agency: NIH / NIAID
Role: Site Principal Investigator
Title: Zika natural history study in Guatemala
Funding Agency: NIH
Role: Principal Investigator
Title: An integrated one health approach to detect and respond to emerging disease threats in high-risk region of Central America
Funding Agency: NIH / CDC
Role: Co-Investigator
Title: Surveillance for vaccine-preventable disease in children
Funding Agency: CDC
Role: Co-Investigator
Title: A master phase 1/2/3 protocol to investigate the safety, tolerability, and immunogenicity of bivalent BNT162B2 RNA-based vaccine candidate(s) in healthy children
Funding Agency: Pfizer, Inc.
Role: Principal Investigator
Title: A phase 1, open-label dose-finding study to evaluate safety, tolerability, and immunogenicity and phase 2/3 placebo controlled, observer-blinded safety, tolerability, and immunogenicity study of SARS-CoV-2RNA vaccine candidate against COVID-19 in healthy children and young adults
Funding Agency: Pfizer, Inc.
Role: Principal Investigator
Title: A phase 2b, open-label study to evaluate the safety, tolerability, and immunogenicity of vaccine candidate BNT162b2 in immunocompromised participants ≥2 years of age
Funding Agency: Pfizer, Inc.
Role: Principal Investigator
Title: A phase 2/3 single-arm, open-label study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of remdesivir (GD-5734) in participants from birth to <18 Years of age with COVID-19
Funding Agency: Gilead Sciences
Role: Principal Investigator
Title: Comparison of high vs. standard dose influenza vaccine in pediatric solid organ transplant recipients
Funding Agency: NIH / NIAID
Role: Site Principal Investigator
Title: A phase 2/3, two-part, open-label, dose escalation, age de-escalation and randomized, observer-blind, placebo-controlled expansion study to evaluate the safety, tolerability, reactogenicity, and effectiveness of mRNA-1273 SARS-CoV-2 vaccine in healthy children 6 months to < 12 years of age
Funding Agency: NIH / NIAID / VTEU
Role: Principal Investigator
Title: Human biomimetics for mucosal infections
Funding Agency: NIH/NIAID
Role: Sub-Investigator
Title: Observation, prospective cohort study of the immunogenicity and safety of SARS-CoV-2 vaccines administered during pregnancy or post-partum and evaluation of antibody transfer and durability in infants
Funding Agency: NIH / NIAID / VTEU
Role: Sub-Investigator
Title: A phase 1/2a trial of the safety, tolerability, and immunogenicity of PIV5-vectored RSV vaccine (BLB-201) in RSV seronegative and seropositive infants and children
Funding Agency: Blue Lake Biotechnology, Inc.
Role: Site Principal Investigator
Title: A phase 2 randomized, open-label, multisite trial to inform public health strategies involving the use of MVA-BN vaccine for Mpox
Funding Agency: NIH / NIAID / VTEU
Role: Sub-Investigator
Title: Pandemic Threat Technology Center
Funding Agency: BCM / Philanthropic Funding
Role: Co-Director
Title: A proposal for outpatient antimicrobial stewardship with the Texas Children’s Health Plan
Funding Agency: Pew Charitable Trusts
Role: Principal Investigator