TRISH Publications

Pachade S, Coronado I, Abdelkhaleq R, Yan J, Salazar-Marioni S, Jagolino A, et al. Detection of Stroke with Retinal Microvascular Density and Self-Supervised Learning Using OCT-A and Fundus Imaging. J Clin Med. 2022;11(24). DOI

H-C, Lee W, Kowsari K, Weisholtz DS, Yoo S-S. Effects of focused ultrasound pulse duration on stimulating cortical and subcortical motor circuits in awake sheep. PLOS ONE. 2022;17(12):e0278865. DOI

Puscas M, Martineau G, Bhella G, Bonnen PE, Carr P, Lim R, et al. Rare diseases and space health: optimizing synergies from scientific questions to care. NPJ Microgravity. 2022;8(1):58. DOI

Simmons P, Trujillo M, McElroy T, Binz R, Pathak R, Allen AR. Evaluating the effects of low-dose simulated galactic cosmic rays on murine hippocampal-dependent cognitive performance. Frontiers in Neuroscience. 2022;16. DOI

Peng M, Curry SM, Liu Y, Lohawala H, Sharma G, Sharma TP. The ex vivo human translaminar autonomous system to study spaceflight associated neuro-ocular syndrome pathogenesis. NPJ Microgravity. 2022;8(1):44. DOI

Pohlen M, Carroll D, Kim Prisk G, Sawyer AJ. Overview of Lunar Dust Toxicity Risk. NPJ Microgravity. 2022;8(1):55. DOI

Sempionatto JR, Lasalde-Ramírez JA, Mahato K, Wang J, Gao W. Wearable chemical sensors for biomarker discovery in the omics era. Nature Reviews Chemistry. 2022;6(12):899-915. DOI

Smith T, Peterman A, Donoviel D. Exponential Medicine: Challenges of Human Spaceflight Bringing Innovations for Earth — A Case Study. In: Friebe M, editor. Novel Innovation Design for the Future of Health: Entrepreneurial Concepts for Patient Empowerment and Health Democratization. Cham: Springer International Publishing; 2022. p. 71-8. DOI

Polutchko SK, Stewart JJ, McNamara M, Doherty Garcia N, López-Pozo M, Adams WW, et al. Lemna as a Sustainable, Highly Nutritious Crop: Nutrient Production in Different Light Environments. Nutraceuticals. 2022;2(4):350-64. DOI

Antonsen E, Monti, A, Charvat, J, Connell, ES, Reynolds, RJ, Abukmail, A, Marotta, K, Brown, C. Directed Acyclic Graphs: A Tool for Understanding the NASA Human Spaceflight System Risks - Human System Risk Board. NASA Technical Reports Server2022. Lin

Xue S, Rogers LRK, Zheng M, He J, Piermarocchi C, Mias GI. Applying differential network analysis to longitudinal gene expression in response to perturbations. Frontiers in Genetics. 2022;13. DOI

Cope H, Willis CRG, MacKay MJ, Rutter LA, Toh LS, Williams PM, et al. Routine omics collection is a golden opportunity for European human research in space and analog environments. Patterns (N Y). 2022;3(10):100550. DOI

Nguyen CN, Urquieta E. Contemporary review of dermatologic conditions in space flight and future implications for long-duration exploration missions. Life Sciences in Space Research. 2022. DOI

Gaidica M, Dantzer B. An implantable neurophysiology platform: Broadening research capabilities in free-living and non-traditional animals. Frontiers in Neural Circuits. 2022;16. DOI

Schimmoller BJ, Trovão NS, Isbell M, Goel C, Heck BF, Archer TC, et al. COVID-19 Exposure Assessment Tool (CEAT): Exposure quantification based on ventilation, infection prevalence, group characteristics, and behavior. Sci Adv. 2022;8(39):eabq0593. DOI

Simmons P, Corley C, Allen AR. Fractionated Proton Irradiation Does Not Impair Hippocampal-Dependent Short-Term or Spatial Memory in Female Mice. Toxics. 2022;10(9). DOI

Burian BK, Ebnali M, Robertson JM, Musson D, Pozner CN, Doyle T, et al. Using extended reality (XR) for medical training and real-time clinical support during deep space missions. Appl Ergon. 2023;106:103902. DOI

Evans AC, Martin KA, Saxena M, Bicher S, Wheeler E, Cordova EJ, et al. Curcumin Nanodiscs Improve Solubility and Serve as Radiological Protectants against Ionizing Radiation Exposures in a Cell-Cycle Dependent Manner. Nanomaterials (Basel). 2022;12(20). DOI

Liao S, Macharoen K, McDonald KA, Nandi S, Paul D. Analysis of Variability of Functionals of Recombinant Protein Production Trajectories Based on Limited Data. Int J Mol Sci. 2022;23(14). DOI

Xiong Y, Hirano H, Lane NE, Nandi S, McDonald KA. Plant-based production and characterization of a promising Fc-fusion protein against microgravity-induced bone density loss. Frontiers in Bioengineering and Biotechnology. 2022;10. DOI

Yarbrough D, Gerecht S. Engineering Smooth Muscle to Understand Extracellular Matrix Remodeling and Vascular Disease. Bioengineering. 2022;9(9):449. DOI

Liu Q, Jimenez M, Inda ME, Riaz A, Zirtiloglu T, Chandrakasan AP, et al. A Threshold-Based Bioluminescence Detector With a CMOS-Integrated Photodiode Array in 65 nm for a Multi-Diagnostic Ingestible Capsule. IEEE Journal of Solid-State Circuits. 2022:1-14. DOI

Reynolds RJ, Scot RT, Turner RT, Iwaniec UT, Bouxsein ML, et al. Validating Casual Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents. Biomedicines 2022, 10(9), 2187. DOI

McNerlin C, Guan F, Bronk L, Lei K, Grosshans D, Young DW, et al. Targeting hippocampal neurogenesis to protect astronauts’ cognition and mood from decline due to space radiation effects. Life Sciences in Space Research. 2022. DOI

Mao XW, Stanbouly S, Chieu B, Sridharan V, Allen AR, Boerma M. Low dose space radiation-induced effects on the mouse retina and blood-retinal barrier integrity. Acta Astronautica. 2022;199:412-9. DOI

Seidler RD, Stern C, Basner M, Stahn AC, Wuyts FL, Zu Eulenburg P. Future research directions to identify risks and mitigation strategies for neurostructural, ocular, and behavioral changes induced by human spaceflight: A NASA-ESA expert group consensus report. Front Neural Circuits. 2022;16:876789. DOI

Holmes ZC, Villa MM, Durand HK, Jiang S, Dallow EP, Petrone BL, et al. Microbiota responses to different prebiotics are conserved within individuals and associated with habitual fiber intake. Microbiome. 2022;10(1):114. DOI

Bokhari RS, Beheshti A, Blutt SE, Bowles DE, Brenner D, Britton R, et al. Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel. Life Sciences in Space Research. 2022. DOI

McCollum CR, Courtney CM, O’Connor NJ, Aunins TR, Ding Y, Jordan TX, et al. Nanoligomers Targeting Human miRNA for the Treatment of Severe COVID-19 Are Safe and Nontoxic in Mice. ACS Biomaterials Science & Engineering. 2022;8(7):3087-106. DOI

Courtney CM, Sharma S, Fallgren C, Weil MM, Chatterjee A, Nagpal P. Reversing radiation-induced immunosuppression using a new therapeutic modality. Life Sciences in Space Research. 2022. DOI

Madrigal P, Singh NK, Wood JM, Gaudioso E, Hernández-Del-Olmo F, Mason CE, et al. Machine learning algorithm to characterize antimicrobial resistance associated with the International Space Station surface microbiome. Microbiome. 2022;10(1):134. DOI

Sharma A, Clemens RA, Garcia O, Taylor DL, Wagner NL, Shepard KA, et al. Biomanufacturing in low Earth orbit for regenerative medicine. Stem Cell Reports. 2022;17(1):1-13. DOI

Wang, M, Yang Y, Min J, Song Y, Tu J, Mukasa D, et al. A Wearable Electrochemical Biosensor for the Monitoring of Metabolites and Nutrients. Nat Biomed Eng. 2022 Aug 15. DOI

Brojakowska A, Kour A, Thel MC, Park E, Bisserier M, et al. Retrospective Analysis of Somatic Mutations and Clonal Hematopoiesis in Astronauts. Commun Biol, 2022 Aug 17:5(1):828. DOI

Buettmann EG, Goldscheitter GM, Hoppock GA, Friedman MA, Suva LJ, Donahue HJ. Similarities Between Disuse and Age-Induced Bone Loss. J Bone Miner Res, 37: 1417-1434. DOI

Bisserier M, Brojakowska A, Saffran N, Kumar Rai A, Lee B, Coleman B, et al. Astronauts Plasma-Derived Exosomes Induced Aberrant EZH2-Mediated H3K27me3 Epigenetic Regulation of the Vitamin D Receptor. Front. Cardiovasc. Med. 16 June 2022. DOI

Yu Y, Li J, Solomon SA, Min J, Tu J, Guo W, et al. All-printed soft human-machine interface for robotic physicochemical sensing. Sci Robot. 2022;7(67):eabn0495. DOI

Schnellmann R, Ntekoumes D, Choudhury MI, Sun S, Wei Z, Gerecht S. Stiffening Matrix Induces Age-Mediated Microvascular Phenotype Through Increased Cell Contractility and Destabilization of Adherens Junctions. Adv Sci (Weinh). 2022:e2201483. DOI

Goukassian D, Arakelyan A, Brojakowska A, Bisserier M, Hakobyan S, Hadri L, et al. Space flight associated changes in astronauts' plasma-derived small extracellular vesicle microRNA: Biomarker identification. Clin Transl Med. 2022;12(6):e845. DOI 

Ayora-Talavera G, Kirstein OD, Puerta-Guardo H, Barrera-Fuentes GA, Ortegòn-Abud D, Che-Mendoza A, et al. SARS-CoV-2 antibody prevalence in a pediatric cohort of unvaccinated children in Mérida, Yucatán, México. PLOS Global Public Health. 2022;2(6):e0000354. DOI 

Hann EC, Overa S, Harland-Dunaway M, Narvaez AF, Le DN, Orozco-Cárdenas ML, et al. A hybrid inorganic–biological artificial photosynthesis system for energy-efficient food production. Nature Food. 2022;3(6):461-71. DOI

Tu D, Basner M, Smith MG, Williams ES, Ryder VE, Romoser AA, et al. Dynamic ensemble prediction of cognitive performance in spaceflight. Scientific Reports. 2022;12(1):11032. DOI

Bhattacharjee S, Liao S, Paul D, Chaudhuri S. Inference on the dynamics of COVID-19 in the United States. Sci Rep. 2022;12(1):2253. DOI

McNulty MJ, Schwartz A, Delzio J, Karuppanan K, Jacobson A, Hart O, et al. Affinity Sedimentation and Magnetic Separation With Plant-Made Immunosorbent Nanoparticles for Therapeutic Protein Purification. Front Bioeng Biotechnol. 2022;10:865481. DOI

McNulty MJ, Xiong YM, Yates K, Karuppanan K, Hilzinger JM, Berliner AJ, et al. Molecular pharming to support human life on the moon, mars, and beyond. Crit Rev Biotechnol. 2021;41(6):849-64. DOI

Bishawi M, Lee FH, Abraham DM, Glass C, Blocker SJ, Cox DJ, et al. Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure. iScience. 2022;25(4):104086. DOI

Zhuang RZ, Lock R, Liu B, Vunjak-Novakovic G. Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances. Nat Biomed Eng. 2022;6(4):327-38. DOI

Macklin BL, Lin YY, Emmerich K, Wisniewski E, Polster BM, Konstantopoulos K, et al. Intrinsic epigenetic control of angiogenesis in induced pluripotent stem cell-derived endothelium regulates vascular regeneration. NPJ Regen Med. 2022;7(1):28. DOI

Jamison DA, Jr., Anand Narayanan S, Trovao NS, Guarnieri JW, Topper MJ, Moraes-Vieira PM, et al. A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection. Eur J Hum Genet. 2022. DOI

Kaplonek P, Cizmeci D, Fischinger S, Collier AR, Suscovich T, Linde C, et al. mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions. Sci Transl Med. 2022;14(645):eabm2311. DOI

Cao X, Weil MM, Wu JC. Clinical Trial in a Dish for Space Radiation Countermeasure Discovery. Life Sciences in Space Research. 2022. DOI

Sempionatto JR, Gao W. Chapter 8 - Wearable chemosensors. In: Morales-Narvaez E, Dincer C, editors. Wearable Physical, Chemical and Biological Sensors: Elsevier; 2022. p. 219-34. DOI

Leung CM, de Haan P, Ronaldson-Bouchard K, Kim G-A, Ko J, Rho HS, et al. A guide to the organ-on-a-chip. Nature Reviews Methods Primers. 2022;2(1):33. DOI

Marshall-Goebel K. Neuro-ocular Effects of Spaceflight. In: Pathak YV, Araújo dos Santos M, Zea L, editors. Handbook of Space Pharmaceuticals. Cham: Springer International Publishing; 2022. p. 261-71. DOI

Nishiga M, Jahng JWS, Wu JC. Ferroptosis of Pacemaker Cells in COVID-19. Circ Res. 2022;130(7):978-80. DOI

Estrada UML, Meeks G, Salazar-Marioni S, Scalzo F, Farooqui M, Vivanco-Suarez J, et al. Quantification of infarct core signal using CT imaging in acute ischemic stroke. Neuroimage Clin. 2022;34:102998. DOI

Urquieta E, Wu J, Hury J, Donoviel D. Establishment of an open biomedical database for commercial spaceflight. Nat Med. 2022. DOI

Ronaldson-Bouchard K, Baldassarri I, Tavakol DN, Graney PL, Samaritano M, Cimetta E, et al. Engineering complexity in human tissue models of cancer. Adv Drug Deliv Rev. 2022;184:114181. DOI

McNulty MJ, Hamada N, Delzio J, McKee L, Nandi S, Longo ML, et al. Functionalizing silica sol–gel with entrapped plant virus-based immunosorbent nanoparticles. Journal of Nanobiotechnology. 2022;20(1):105. DOI

Lee W, Weisholtz DS, Strangman GE, Yoo S-S. Safety Review and Perspectives of Transcranial Focused Ultrasound Brain Stimulation. Brain Neurorehabil. 2021;14(1). DOI

Karlebach G, Aronow B, Baylin SB, Butler D, Foox J, Levy S, et al. Betacoronavirus-specific alternate splicing. Genomics. 2022;114(2):110270. DOI

Kaplonek P, Cizmeci D, Fischinger S, Collier A-r, Suscovich T, Linde C, et al. mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions. Science Translational Medicine.0(0):eabm2311. DOI

Didier KD, Hammer SM, Alexander AM, Rollins KS, Barstow TJ. The acute effects of passive heating on endothelial function, muscle microvascular oxygen delivery, and expression of serum HSP90alpha. Microvasc Res. 2022;142:104356. DOI

Voros J, Rise R, Sherman S, Durell A, Anderson AP, Clark TK. A machine learning approach to identify stochastic resonance in human perceptual thresholds. J Neurosci Methods. 2022;374:109559. DOI

Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, et al. Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2022;119(13):e2023784119. DOI

Finch E, Lowe R, Fischinger S, de St Aubin M, Siddiqui SM, Dayal D, et al. SARS-CoV-2 antibodies protect against reinfection for at least 6 months in a multicentre seroepidemiological workplace cohort. PLoS Biol. 2022;20(2):e3001531. DOI

Wang Y, Tang J, Vimal VP, Lackner JR, DiZio P, Hong P. Crash Prediction Using Deep Learning in a Disorienting Spaceflight Analog Balancing Task. Frontiers in Physiology. 2022;13. DOI

Siddiqui SM, Bowman KA, Zhu AL, Fischinger S, Beger S, Maron JS, et al. Serological Markers of SARS-CoV-2 Reinfection. mBio. 2022:e0214121. DOI

Pena D, Suescun J, Schiess M, Ellmore TM, Giancardo L, Alzheimer's Disease Neuroimaging I. Toward a Multimodal Computer-Aided Diagnostic Tool for Alzheimer's Disease Conversion. Front Neurosci. 2021;15:744190. DOI

Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, et al. System-wide transcriptome damage and tissue identity loss in COVID-19 patients. Cell Reports Medicine. 2022:100522. DOI

Karlebach G, Aronow B, Baylin SB, Butler D, Foox J, Levy S, et al. Betacoronavirus-specific alternate splicing. Genomics. 2022;114(2):110270. DOI

Kaplonek P, Fischinger S, Cizmeci D, Bartsch YC, Kang J, Burke JS, et al. mRNA-1273 vaccine-induced antibodies maintain Fc effector functions across SARS-CoV-2 variants of concern. Immunity. 2022. DOI

DeNapoli R, Buettmann E, Donahue H. Cellular and Molecular Biology in Bone Remodeling. 2022. p. 3-15. DOI

Demmig-Adams B, Polutchko SK, Zenir MC, Fourounjian P, Stewart JJ, López-Pozo M, et al. Intersections: photosynthesis, abiotic stress, and the plant microbiome. Photosynthetica. 2022. DOI

Demmig-Adams B, Lopez-Pozo M, Polutchko SK, Fourounjian P, Stewart JJ, Zenir MC, et al. Growth and Nutritional Quality of Lemnaceae Viewed Comparatively in an Ecological and Evolutionary Context. Plants (Basel). 2022;11(2). DOI

Cromwell RL, Huff JL, Simonsen LC, Patel ZS. Earth-Based Research Analogs to Investigate Space-Based Health Risks. New Space. 2021;9(4):204-16. DOI

Bisserier M, Saffran N, Brojakowska A, Sebastian A, Evans AC, Coleman MA, et al. Emerging Role of Exosomal Long Non-coding RNAs in Spaceflight-Associated Risks in Astronauts. Frontiers in Genetics. 2022;12. DOI

Friedman MA, Abood A, Senwar B, Zhang Y, Maroni CR, Ferguson VL, et al. Genetic variability affects the skeletal response to immobilization in founder strains of the diversity outbred mouse population. Bone Rep. 2021;15:101140. DOI

Miller KH, Sutton E, Pantalos G. Hierarchical Task Analysis Reimagined as a Planning Tool for Surgery During Exploration Space Flight. Surg Innov. 2021:15533506211053210. DOI

Huang Y, Harris BS, Minami SA, Jung S, Shah PS, Nandi S, et al. SARS-CoV-2 spike binding to ACE2 is stronger and longer ranged due to glycan interaction. Biophys J. 2022;121(1):79-90. DOI

Jahng JWS, Wu JC. Cardiac reprogramming via chromatin remodeling by CRISPR activation. Mol Ther. 2021. DOI

Heng W, Solomon S, Gao W. Flexible Electronics and Devices as Human-Machine Interfaces for Medical Robotics. Adv Mater. 2021:e2107902. DOI

Wang C, Shirzaei Sani E, Gao W. Wearable Bioelectronics for Chronic Wound Management. Advanced Functional Materials. 2021:2111022. DOI

Coronado I, Abdelkhaleq R, Yan J, Marioni SS, Jagolino-Cole A, Channa R, et al. Towards Stroke Biomarkers on Fundus Retinal Imaging: A Comparison Between Vasculature Embeddings and General Purpose Convolutional Neural Networks. Annu Int Conf IEEE Eng Med Biol Soc. 2021;2021:3873-6. DOI

Nilles EJ, Siddiqui SM, Fischinger S, Bartsch YC, de Saint Aubin M, Zhou G, et al. Epidemiological and immunological features of obesity and SARS-CoV-2. medRxiv. 2020. DOI

Kim HN, Richardson KK, Krager KJ, Ling W, Simmons P, Allen AR, et al. Simulated Galactic Cosmic Rays Modify Mitochondrial Metabolism in Osteoclasts, Increase Osteoclastogenesis and Cause Trabecular Bone Loss in Mice. Int J Mol Sci. 2021;22(21). DOI

Kiffer FC, Luitel K, Tran FH, Patel RA, Guzman CS, Soler I, et al. Effects of a 33-ion sequential beam galactic cosmic ray analog on male mouse behavior and evaluation of CDDO-EA as a radiation countermeasure. Behav Brain Res. 2021:113677. DOI

Vimal VP, DiZio P, Lackner JR. The role of spatial acuity in a dynamic balancing task without gravitational cues. Exp Brain Res. 2021. DOI

Soler I, Yun S, Reynolds RP, Whoolery CW, Tran FH, Kumar PL, et al. Multi-Domain Touchscreen-Based Cognitive Assessment of C57BL/6J Female Mice Shows Whole-Body Exposure to (56)Fe Particle Space Radiation in Maturity Improves Discrimination Learning Yet Impairs Stimulus-Response Rule-Based Habit Learning. Front Behav Neurosci. 2021;15:722780. DOI

McNulty MJ, Berliner AJ, Negulescu PG, McKee L, Hart O, Yates K, et al. Evaluating the Cost of Pharmaceutical Purification for a Long-Duration Space Exploration Medical Foundry. Front Microbiol. 2021;12:700863. DOI

Lock R, Al Asafen H, Fleischer S, Tamargo M, Zhao Y, Radisic M, et al. A framework for developing sex-specific engineered heart models. Nat Rev Mater. 2021:1-19. DOI

Beheshti A, McDonald JT, Hada M, Takahashi A, Mason CE, Mognato M. Genomic Changes Driven by Radiation-Induced DNA Damage and Microgravity in Human Cells. Int J Mol Sci. 2021;22(19). DOI

Bisserier M, Shanmughapriya S, Rai AK, Gonzalez C, Brojakowska A, Garikipati VNS, et al. Cell-Free Mitochondrial DNA as a Potential Biomarker for Astronauts' Health. J Am Heart Assoc. 2021:e022055. DOI

Kaplonek P, Wang C, Bartsch Y, Fischinger S, Gorman MJ, Bowman K, et al. Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19. bioRxiv. 2021. DOI

Wong MC, Ng BK, Tian I, Sobhiyeh S, Pagano I, Dechenaud M, et al. A pose-independent method for accurate and precise body composition from 3D optical scans. Obesity (Silver Spring). 2021. DOI

Song Y, Wright JG, Anderson MJ, Rajendran S, Ren Z, Hua DH, et al. Quantitative Detection of Cathepsin B Activity in Neutral pH Buffers Using Gold Microelectrode Arrays: Toward Direct Multiplex Analyses of Extracellular Proteases in Human Serum. ACS Sens. 2021. DOI

J. Tyson McDonald FJE, Deanne Taylor, Robert J. Griffin, Waldemar Priebe, Mark R. Emmett, Mohammad M. Sajadi, Anthony D. Harris, Jean Clement, Joseph M. Dybas, Nukhet Aykin-Burns, Joseph W. Guarnieri, Larry N. Singh, Peter Grabham, Stephen B. Baylin, Aliza Yousey, Andrea N. Pearson, Peter M. Corry, Amanda Saravia-Butler, Thomas R. Aunins, Sadhana Sharma, Prashant Nagpal, Cem Meydan, Jonathan Foox, Christopher Mozsary, Bianca Cerqueira, Viktorija Zaksas, Urminder Singh, Eve Syrkin Wurtele, Sylvain V. Costes, Gustavo Gastão Davanzo, Diego Galeano, Alberto Paccanaro, Suzanne L. Meinig, Robert S. Hagan, Natalie M. Bowman, Matthew C. Wolfgang, Selin Altinok, Nicolae Sapoval, Todd J. Treangen, Pedro M. Moraes-Vieira, Charles Vanderburg, Douglas C. Wallace, Jonathan Schisler, Christopher E. Mason, Anushree Chatterjee, Robert Meller, Afshin Beheshti,. Role of miR-2392 in Driving SARS-CoV-2 Infection. Cell Reports 2021. DOI

Vunjak-Novakovic G, Ronaldson-Bouchard K, Radisic M. Organs-on-a-chip models for biological research. Cell. 2021;184(18):4597-611. DOI

Minqiang Wang YY, Wei Gao Laser-engraved graphene for flexible and wearable electronics. Trends in Chemistry. 2021. DOI

Kahlenberg ZB, Carroll DJ, Cristea O, Urquieta E, Bissada NK, Jones JA. Urologic Innovation in the Spaceflight Environment: Challenges, Opportunities, and Future Directions. Medical Research Archives. 2021;9(9). DOI

Matthew J. McNulty, Yongao (Mary) Xiong, Kevin Yates, Kalimuthu Karuppanan, Jacob M. Hilzinger, Aaron J. Berliner, Jesse Delzio, Adam P. Arkin, Nancy E. Lane, Somen Nandi & Karen A. McDonald (2021): Molecular pharming to support human life on the moon, mars, and beyond, Critical Reviews in Biotechnology, DOI

Zheng, M., Domanskyi, S., Piermarocchi, C. et al. Visibility graph based temporal community detection with applications in biological time series. Sci Rep 11, 5623 (2021). DOI

Sophie C. Rosahl, Claudia Covarrubias, Jimmy H. Wu, and Emmanuel Urquieta.Therapeutic Hypothermia and Temperature Management. Ahead of print. DOI

Allaway, H.C.M., Pierson, R.A., Invik, J. et al. A rodent model of human dose-equivalent progestin-only implantable contraception. Reprod Biol Endocrinol 19, 47 (2021). DOI

Voros JL, Sherman SO, Rise R, Kryuchkov A, Stine P, Anderson AP and Clark TK. Galvanic Vestibular Stimulation Produces Cross-Modal Improvements in Visual Thresholds. Front Neurosci. 2021 Mar 31;15:640984. DOI

Swinton C, Kiffer F, McElroy T, Wang J, Sridharan V, Boerma M, Allen A. Effects of 16O charged-particle irradiation on cognition, hippocampal morphology and mutagenesis in female mice. Behav Brain Res. 2021 Jun 11;407:113257. DOI.

Davis C, Allen A and Bowles DE. Consequences of space radiation on the brain and cardiovascular system. 2021, Journal of Environmental Science and Health, Part C, 39:2, 180-218, DOI

Tu J and Gao W. Ethical Considerations of Wearable Technologies in Human Research. Adv Healthc Mater. 2021 Apr 18;e2100127. DOI

Chancellor J, Nowadly C,Williams J, Aunon-Chancellor S, Chesal M, Looper J and Newhauser W. 2021 Everything you wanted to know about space radiation but were afraid to ask, Journal of Environmental Science and Health, Part C, 39:2, 113-128, DOI

Willey J, Britten RA, Blaber E, Tahimic CGT, Chancellor J, Mortreux M, Sanford L, Kubik AJ, Delp MD and Mao XW. 2021. The individual and combined effects of spaceflight radiation and microgravity on biologic systems and functional outcomes, Journal of Environmental Science and Health, Part C, 39:2, 129-179. DOI

LaPelusa M, Donoviel D, Branzini SE, Carlson PE, Jr., Culler S, Cheema AK, et al. Microbiome for Mars: surveying microbiome connections to healthcare with implications for long-duration human spaceflight, virtual workshop, July 13, 2020. Microbiome. 2021;9(1):2. DOI.

Mias GI, Singh VV, Rogers LRK, Xue S, Zheng M, Domanskyi S, Kanada M, Piermarocchi C, He J. Longitudinal saliva omics responses to immune perturbation: a case study. Sci Rep. 2021 Jan 12;11(1):710. DOI.

Penninckx S, Pariset E, Acuna AU, Lucas S, Costes SV. Considering Cell Proliferation to Optimize Detection of Radiation-Induced 53BP1 Positive Foci in 15 Mouse Strains Ex Vivo. Radiat Res. 2021;195(1):47-59. DOI.

Rosahl SC, Covarrubias C, Wu JH, Urquieta E. Staying Cool in Space: A Review of Therapeutic Hypothermia and Potential Application for Space Medicine. Ther Hypothermia Temp Manag. 2021. DOI.

Sapoval N, Mahmoud M, Jochum M, Liu Y, Elworth RAL, Wang Q, Albin D, Ogilvie H, Lee MD, Villapol S, Hernandez K, Maljkovic Berry I, Foox J, Beheshti A, Ternus K, Aagaard K, Posada D, Mason C, Sedlazeck FJ, Treangen TJ. Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission. Genome Res. 2021. Epub ahead of print. DOI.

Bartsch YC, Fischinger S, Siddiqui SM, Chen Z, Yu J, Gebre M, et al. Discrete SARS-CoV-2 antibody titers track with functional humoral stability. Nature Communications. 2021;12(1):1018. DOI.

Eller KA, Aunins TR, Courtney CM, Campos JK, Otoupal PB, Erickson KE, et al. Facile accelerated specific therapeutic (FAST) platform develops antisense therapies to counter multidrug-resistant bacteria. Communications Biology. 2021;4(1):331. DOI.

Fan S, Inam ME, Peña D, Chen PR, Giancardo L, editors. X-Ray Based Automatic Detection Of Brain Coil Compaction Using Unsupervised Learning. 2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI). 2021. DOI.

Gómez ML, Huang X, Alvarez D, He W, Baysal C, Zhu C, et al. Contributions of the international plant science community to the fight against human infectious diseases – part 1: epidemic and pandemic diseases. Plant Biotechnology Journal. 2021. DOI.

He W, Baysal C, Gómez ML, Huang X, Alvarez D, Zhu C, et al. Contributions of the international plant science community to the fight against infectious diseases in humans – part 2: affordable drugs in edible plants for endemic and re‐emerging diseases. Plant Biotechnology Journal. 2021. DOI.

Kaplonek P, Fischinger S, Cizmeci D, Bartsch YC., Kang J, Burke JS., Shin SA, Dayal D, Martin P, Mann C, Fatima A, Julg B, Nilles E,. Musk ER, Menon AS,. Krammer F, Saphire EO, Carfi A, and Alter G. Resilient Fc-Effector Functions Across SARS-CoV-2 Variants of Concern Following mRNA-1273 Vaccination. Immunity. 2021. DOI.

Lee W, Weisholtz DS, Strangman GE, Yoo S-S. Safety Review and Perspectives of Transcranial Focused Ultrasound Brain Stimulation. Brain & Neurorehabilitation. 2021;14(1). DOI.

Mitchell R, Frederick NE, Holzman ER, Agobe F, Allaway HCM, Bagher P. Ifetroban Reduces Coronary Artery Dysfunction in a Mouse Model of Duchenne Muscular Dystrophy. AJP Heart and Circulatory Physiology. 2021. DOI.

Nguyen J, Lin Y-Y, Gerecht S. The next generation of endothelial differentiation: Tissue-specific ECs. Cell Stem Cell. 2021. DOI.

Reynolds R, Little MP, Day S, Charvat J, Blattnig S, Huff J, et al. Cancer incidence and mortality in the USA Astronaut Corps, 1959–2017. Occupational and Environmental Medicine. 2021:oemed-2020. DOI.

Silverman JD, Bloom RJ, Jiang S, Durand HK, Dallow E, Mukherjee S, et al. “Measuring and mitigating PCR bias in microbiota datasets.” PLOS Computational Biology. 2021;17(7):e1009113. DOI.

Stewart JJ, Adams WW, López-Pozo M, Doherty Garcia N, McNamara M, Escobar CM, et al. Features of the Duckweed Lemna That Support Rapid Growth under Extremes of Light Intensity. Cells. 2021;10(6):1481. DOI.

Sujit SJ, Bonfante E, Aein A, Coronado I, Riascos-Castaneda R, Giancardo L. Deep Learning Enabled Brain Shunt Valve Identification Using Mobile Phones. Computer Methods and Programs in Biomedicine. 2021:106356. DOI.

Silverman JD, Bloom RJ, Jiang S, Durand HK, Dallow E, Mukherjee S, et al. Measuring and mitigating PCR bias in microbiota datasets. PLOS Computational Biology. 2021;17(7):e1009113. DOI.

Juhl OJ, Buettmann EG, Friedman MA, DeNapoli RC, Hoppock GA, Donahue HJ. Update on the effects of microgravity on the musculoskeletal system. npj Microgravity. 2021;7(1):28. DOI.

Worman ZF, Dempsey R, Domingo C, Donoviel D. NASA-backed launch for jobless postdocs. Nature. 2020; 587(197). DOI.

Kiffer F, Alexander T, Anderson J, Groves T, McElroy T, Wang J, et al. Late Effects of (1)H + (16)O on Short-Term and Object Memory, Hippocampal Dendritic Morphology and Mutagenesis. Front Behav Neurosci. 2020;14:96. DOI.

Anderson MJ, Song Y, Fan H, Wright JG, Ren Z, Hua DH, et al. Simultaneous, multiplex quantification of protease activities using a gold microelectrode array. Biosens Bioelectron. 2020;165:112330. DOI.

J. Voros et al., "Multi-modal Stochastic Resonance to Enhance Astronaut Perceptual Performance: Experimental Design," 2020 IEEE Aerospace Conference, Big Sky, MT, USA, 2020, pp. 1-8. DOI.

Sapoval N, Mahmoud M, Jochum MD, Liu Y, Elworth RAL, Wang Q, et al. Hidden genomic diversity of SARS-CoV-2: implications for qRT-PCR diagnostics and transmission. bioRxiv. 2020. DOI.

Paul AM, Cheng-Campbell M, Blaber EA, Anand S, Bhattacharya Sharmila, Zwart S, et al. Beyond Low-Earth Orbit: Characterizing the Immune Profile Following Simulated Spaceflight Conditions for Deep Space Missions. Cell Press. 2020. DOI.

Wuu Y, Hu B, Okunola H, Paul AM, Blaber EA, Cheng-Campbell M, et al. LET Dependent Low Dose and Synergistic Inhibition of Human Angiogenesis by Charged Particles: Validation of Mi RNAs that Drive Inhibition. Cell Press. 2020 DOI.

Malkani S, Cekanaviciute E, Mortreux M, Okunola H, Tarbier M, Schreurs A, et al. Circulating miRNA Signature Predicts and Rescues Spaceflight Associated Health Risks. Cell Press. 2020. DOI.

Wuu Y, Hu B, Okunola H, Paul AM, Blaber EA, Cheng-Campbell M, et al. LET-Dependent Low Dose and Synergistic Inhibition of Human Angiogenesis by Charged Particles: Validation of miRNAs that Drive Inhibition. iScience. 2020; 23(12):epub. DOI.

Malkani S, Chin CR, Cekanaviciute E, Mortreux M, Okinula H, Tarbier M, et al. Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development. Cell Rep. 2020;33(10):108448. DOI.

Paul AM, Cheng-Campbell M, Blaber EA, Anand S, Bhattacharya S, Zwart SR, et al. Beyond Low-Earth Orbit: Characterizing Immune and microRNA Differentials following Simulated Deep Spaceflight Conditions in Mice. iScience. 2020;23(12):101747. DOI.

Holmes ZC, Silverman JD, Dressman HK, Wei Z, Dallow EP, Armstrong SC, et al. Short-Chain Fatty Acid Production by Gut Microbiota from Children with Obesity Differs According to Prebiotic Choice and Bacterial Community Composition. mBio. 2020;11(4). DOI.

Silverman JD, Roche K, Mukherjee S, David LA. Naught all zeros in sequence count data are the same. Comput Struct Biotechnol J. 2020;18:2789-98. DOI.

Villa MM, Bloom RJ, Silverman JD, Durand HK, Jiang S, Wu A, et al. Interindividual Variation in Dietary Carbohydrate Metabolism by Gut Bacteria Revealed with Droplet Microfluidic Culture. mSystems. 2020;5(3). DOI.

Demmig-Adams B, Lopez-Pozo M, Stewart JJ, Adams WW, 3rd. Zeaxanthin and Lutein: Photoprotectors, Anti-Inflammatories, and Brain Food. Molecules. 2020;25(16). DOI.

Stewart JJ, Adams WW, 3rd, Escobar CM, Lopez-Pozo M, Demmig-Adams B. Growth and Essential Carotenoid Micronutrients in Lemna gibba as a Function of Growth Light Intensity. Front Plant Sci. 2020;11:480. DOI.

Demmig-Adams B, Stewart JJ, Lopez-Pozo M, Polutchko SK, Adams WW, 3rd. Zeaxanthin, a Molecule for Photoprotection in Many Different Environments. Molecules. 2020;25(24). DOI.

Dmochowski GM, Shereen AD, Berisha D, Dmochowski JP. Near-Infrared Light Increases Functional Connectivity with a Non-thermal Mechanism. Cerebral Cortex Communications. 2020;1(1). DOI.

Friedman MA, Abood A, Senwar B, Zhang Y, Maroni CR, Ferguson VL, et al. Genetic Variability affects the Skeletal Response to Unloading. bioRxiv. 2020:2020.06.26.174326. DOI.

Min J, Sempionatto JR, Teymourian H, Wang J, Gao W. Wearable electrochemical biosensors in North America. Biosens Bioelectron. 2021;172:112750. DOI.

Song Y, Min J, Yu Y, Wang H, Yang Y, Zhang H, et al. Wireless battery-free wearable sweat sensor powered by human motion. Sci Adv. 2020;6(40). DOI.

Torrente-Rodriguez RM, Lukas H, Tu J, Min J, Yang Y, Xu C, et al. SARS-CoV-2 RapidPlex: A Graphene-Based Multiplexed Telemedicine Platform for Rapid and Low-Cost COVID-19 Diagnosis and Monitoring. Matter. 2020;3(6):1981-98. DOI.

Lukas H, Xu C, Yu Y, Gao W. Emerging Telemedicine Tools for Remote COVID-19 Diagnosis, Monitoring, and Management. ACS Nano. 2020;14(12):16180-93. DOI.

Scott RA, Tarver WJ, Brunstetter TJ, Urquieta E. Optic Nerve Tortuosity on Earth and in Space. Aerosp Med Hum Perform. 2020;91(2):91-7. DOI. 

McDonald KA, Holtz RB. From Farm to Finger Prick-A Perspective on How Plants Can Help in the Fight Against COVID-19. Front Bioeng Biotechnol. 2020;8:782. DOI.

Yashar M, Marquez J, Menon J, Torron I, editors. Preliminary Design of an 'Autonomous Medical Response Agent' Interface Prototype for Long-Duration Spaceflight2020; Cham: Springer International Publishing. DOI.

Mias GI, Singh VV, Rogers LRK, Xue S, Zheng M, Domanskyi S, et al. Longitudinal Saliva Omics Responses to Immune Perturbation: A Case Study. bioRxiv. 2020:2020.06.16.156133. DOI.

Domanskyi S, Piermarocchi C, Mias GI. PyIOmica: longitudinal omics analysis and trend identification. Bioinformatics. 2020;36(7):2306-7. DOI.

Zheng M, Domanskyi S, Piermarocchi C, Mias GI. Visibility Graph Based Community Detection for Biological Time Series. bioRxiv. 2020:2020.03.02.973263. DOI.

Norsk P. Adaptation of the cardiovascular system to weightlessness: Surprises, paradoxes and implications for deep space missions. Acta Physiol (Oxf). 2020;228(3):e13434. DOI. 

Shelhamer M, Bloomberg J, LeBlanc A, Prisk GK, Sibonga J, Smith SM, et al. Selected discoveries from human research in space that are relevant to human health on Earth. NPJ Microgravity. 2020;6:5. DOI. 

Pariset E, Penninckx S, Kerbaul CD, Guiet E, Macha AL, Cekanaviciute E, et al. 53BP1 Repair Kinetics for Prediction of In Vivo Radiation Susceptibility in 15 Mouse Strains. Radiat Res. 2020;194(5):485-99. DOI. 

Almeida-Porada G, Atala AJ, Porada CD. Therapeutic Mesenchymal Stromal Cells for Immunotherapy and for Gene and Drug Delivery. Mol Ther Methods Clin Dev. 2020;16:204-24. DOI.

Reynolds R, Little MP, Day SM, Charvat J, Blatting S, Huff JL, et al. Cancer Incidence and Mortality in the U.S. Astronaut Corps, 1959-2017. Res Square. 2020. DOI.

Riccio G, Au R, Emmerik Rv, Eslami M. Situated Precision Healthcare in the Smart Medical Home: Bringing NASA's Research Strategy down to Earth. Advances in Geriatric Medicine and Research. 2020;2(3):e200017. DOI.

Badran BW, Caulfield KA, Lopez JW, Cox C, Stomberg-Firestein S, DeVries WH, et al. Personalized TMS helmets for quick and reliable TMS administration outside of a laboratory setting. Brain Stimul. 2020;13(3):551-3. DOI.

Badran BW, Caulfield KA, Cox C, Lopez JW, Borckardt JJ, DeVries WH, et al. Brain stimulation in zero gravity: transcranial magnetic stimulation (TMS) motor threshold decreases during zero gravity induced by parabolic flight. NPJ Microgravity. 2020;6:26. DOI.

Caulfield KA, Lopez JW, Cox CE, Roberts DR, McTeague LM. A new, open-source 3D-printed transcranial magnetic stimulation (TMS) coil tracker holder for double blind, sham-controlled neuronavigation studies. Brain Stimul. 2020;13(3):600-2. DOI. 

Rasmussen JC, Kwon S, Pinal A, Bareis A, Velasquez FC, Janssen CF, et al. Assessing lymphatic route of CSF outflow and peripheral lymphatic contractile activity during head-down tilt using near-infrared fluorescence imaging. Physiol Rep. 2020;8(4):e14375. DOI.

Urbaniak C, Wong S, Tighe S, Arumugam A, Liu B, Parker CW, et al. Validating an Automated Nucleic Acid Extraction Device for Omics in Space Using Whole Cell Microbial Reference Standards. Front Microbiol. 2020;11:1909. DOI.

Vimal VP, Zheng H, Hong P, Fakharzadeh LN, Lackner JR, DiZio P. Characterizing Individual Differences in a Dynamic Stabilization Task Using Machine Learning. Aerosp Med Hum Perform. 2020;91(6):479-88. DOI.

Patel ZS, Brunstetter TJ, Tarver WJ, Whitmire AM, Zwart SR, Smith SM, et al. Red risks for a journey to the red planet: The highest priority human health risks for a mission to Mars. NPJ Microgravity. 2020;6(1):33. DOI.

Hammel P, Marchetti A, Zenhausern F. AR222, AR249, AS274, AS702 and AS708 antibodies recognize the spike S protein from SARS-CoV-2 by ELISA. Antib Rep. 2020;3(4):e220. DOI. 

Lacombe J, Zenhausern F, Cosson P. AI334, AQ806, AR222, AR249, AS274, AS708, RB572, RB574 and RB596 antibodies recognize SARS-CoV-2 viral particles by dot blot. Antib Rep. 2020;3(4):e273. DOI.

Hammel P, Zenhausern F. RB620 and RB621 antibodies recognize a peptide of the SARS-CoV-2 E protein by ELISA. Antib Rep. 2020;3(4):e238. DOI. 

Marchetti A, Zenhausern F. AR222, AR249, AS274, AS702 and AS708 antibodies recognize the spike S protein from SARS-CoV-2 by immunofluorescence. Antib Rep. 2020;3(4):e228. DOI. 

Marchetti A, Zenhausern F. RB572, RB574 and RB576 antibodies recognize the membrane M protein from SARS-CoV-2 by immunofluorescence. Antib Rep. 2020;3(4):e231. DOI. 

Marchetti A, Zenhausern F. The RB621 antibody recognizes the envelope E protein from SARS-CoV-2 by immunofluorescence. Antib Rep. 2020;3(4):e239. DOI. 

Pariset E, Bertucci A, Petay M, Malkani S, Lopez Macha A, Paulino Lima IG, et al. DNA Damage Baseline Predicts Resilience to Space Radiation and Radiotherapy. Cell Rep. 2020;33(10):108434. DOI.

Kiffer F, Boerma M, Allen A. Behavioral effects of space radiation: A comprehensive review of animal studies. Life Sci Space Res (Amst). 2019;21:1-21. DOI.

Levy M, Bertram JR, Eller KA, Chatterjee A, Nagpal P. Near-Infrared-Light-Triggered Antimicrobial Indium Phosphide Quantum Dots. Angew Chem Int Ed Engl. 2019;58(33):11414-8. DOI. 

Silverman JD, Bloom RJ, Jiang S, Durand HK, Mukherjee S, David LA. Measuring and Mitigating PCR Bias in Microbiome Data. bioRxiv. 2019:604025. DOI.

Villa MM, Bloom RJ, Silverman JD, Durand HK, Jiang S, Wu A, et al. High-throughput isolation and culture of human gut bacteria with droplet microfluidics. bioRxiv. 2019:630822. DOI.

Strangman G, Sawyer A, Fabre K, Urquieta E, Hury J, Wu J, et al. Deep-space applications for point-of-care technologies. Current Opinion in Biomedical Engineering. 2019;11:45-50. DOI.

Jimenez M, Langer R, Traverso G. Microbial therapeutics: New opportunities for drug delivery. J Exp Med. 2019;216(5):1005-9. DOI.

Marshall-Goebel K, Damani R, Bershad EM. Brain Physiological Response and Adaptation During Spaceflight. Neurosurgery. 2019;85(5):E815-E21. DOI.

Marshall-Goebel K. Neuro-ocular Effects of Spaceflight. In: Pathak Y, Araújo dos Santos M, Zea L, editors. Handbook of Space Pharmaceuticals. Cham: Springer International Publishing; 2019. p. 1-11. DOI.

Zhu B, Kwon S, Rasmussen JC, Litorja M, Sevick-Muraca EM. Comparison of NIR Versus SWIR Fluorescence Image Device Performance Using Working Standards Calibrated With SI Units. IEEE Trans Med Imaging. 2020;39(4):944-951. DOI.

Vimal VP, DiZio P, Lackner JR. Learning and long-term retention of dynamic self-stabilization skills. Exp Brain Res. 2019;237(11):2775-87. DOI.

Silverman JD, Durand HK, Bloom RJ, Mukherjee S, David LA. Dynamic linear models guide design and analysis of microbiota studies within artificial human guts. Microbiome. 2018;6(1):202. DOI.